YOL012C / HTZ1

Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin

Zygosity: Homozygous strain
fixedexpanded
Profile for YOL012C / HTZ1

Click on Significant Values for Screen Details ID:SGTC_18|Compound:0111-0177|FD-Score:4.45|P-value:2.07E-5 ID:SGTC_22|Compound:0964-0034|FD-Score:5.32|P-value:4.66E-7 ID:SGTC_67|Compound:0335-0847|FD-Score:4.11|P-value:7.68E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:7.33|P-value:6.57E-12 ID:SGTC_103|Compound:0844-0104|FD-Score:-3.41|P-value:7.37E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:4.09|P-value:8.08E-5 ID:SGTC_142|Compound:0335-0849|FD-Score:4.15|P-value:6.57E-5 ID:SGTC_149|Compound:3970-0822|FD-Score:3.47|P-value:6.93E-4 ID:SGTC_200|Compound:k038-0079|FD-Score:4.03|P-value:1.04E-4 ID:SGTC_210|Compound:3551-0445|FD-Score:5.54|P-value:1.63E-7 ID:SGTC_212|Compound:3807-4682|FD-Score:6.01|P-value:1.46E-8 ID:SGTC_214|Compound:4373-3496|FD-Score:3.76|P-value:2.64E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:5.47|P-value:2.30E-7 ID:SGTC_229|Compound:benomyl|FD-Score:8.36|P-value:5.76E-15 ID:SGTC_286|Compound:k060-0067|FD-Score:4.56|P-value:1.29E-5 ID:SGTC_294|Compound:k038-0071|FD-Score:4.37|P-value:2.85E-5 ID:SGTC_310|Compound:1273-0058|FD-Score:-3.67|P-value:3.17E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:8.13|P-value:2.90E-14 ID:SGTC_367|Compound:0335-0881|FD-Score:5.53|P-value:1.69E-7 ID:SGTC_436|Compound:n,n-dimethylsphingosine|FD-Score:5.83|P-value:3.80E-8 ID:SGTC_442|Compound:cape|FD-Score:4.37|P-value:2.78E-5 ID:SGTC_444|Compound:curcumin|FD-Score:-3.54|P-value:4.90E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.51|P-value:1.89E-7 ID:SGTC_514|Compound:4466-0038|FD-Score:5.19|P-value:8.52E-7 ID:SGTC_580|Compound:1123-0028|FD-Score:5.17|P-value:9.48E-7 ID:SGTC_673|Compound:1082-0474|FD-Score:4.39|P-value:2.57E-5 ID:SGTC_771|Compound:0250-0039|FD-Score:5.93|P-value:2.24E-8 ID:SGTC_772|Compound:k072-0172|FD-Score:4.51|P-value:1.60E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:4.27|P-value:4.19E-5 ID:SGTC_840|Compound:0245-0196|FD-Score:3.44|P-value:7.82E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:8.69|P-value:4.95E-16 ID:SGTC_912|Compound:3474-0017|FD-Score:5.33|P-value:4.38E-7 ID:SGTC_919|Compound:tnp00227|FD-Score:3.89|P-value:1.69E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:4.14|P-value:6.89E-5 ID:SGTC_1013|Compound:4112-3890|FD-Score:5.36|P-value:3.73E-7 ID:SGTC_1147|Compound:3809-1045|FD-Score:3.36|P-value:9.89E-4 ID:SGTC_1206|Compound:3978-0017|FD-Score:3.37|P-value:9.59E-4 ID:SGTC_1226|Compound:3909-7979|FD-Score:4.41|P-value:2.37E-5 ID:SGTC_1260|Compound:0700-1617|FD-Score:3.75|P-value:2.80E-4 ID:SGTC_1352|Compound:1496-0991|FD-Score:4.19|P-value:5.63E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:3.49|P-value:6.51E-4 ID:SGTC_1468|Compound:k284-1086|FD-Score:3.79|P-value:2.42E-4 ID:SGTC_1539|Compound:benzyladenosine|FD-Score:3.86|P-value:1.86E-4 ID:SGTC_1564|Compound:D-Arginine|FD-Score:4.14|P-value:6.91E-5 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.61|P-value:4.51E-4 ID:SGTC_1599|Compound:8-chlro-1-tetrahydronorharmanone|FD-Score:3.68|P-value:3.46E-4 ID:SGTC_1643|Compound:st009866|FD-Score:3.89|P-value:1.69E-4 ID:SGTC_1728|Compound:st035614|FD-Score:3.58|P-value:4.94E-4 ID:SGTC_1870|Compound:st057514|FD-Score:3.85|P-value:1.93E-4 ID:SGTC_1875|Compound:nocodazole|FD-Score:4.07|P-value:8.81E-5 ID:SGTC_1911|Compound:st060208|FD-Score:3.48|P-value:6.84E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-3.54|P-value:4.93E-4 ID:SGTC_2044|Compound:5102272|FD-Score:3.62|P-value:4.31E-4 ID:SGTC_2060|Compound:5238662|FD-Score:4.63|P-value:9.90E-6 ID:SGTC_2061|Compound:5245884|FD-Score:5.03|P-value:1.79E-6 ID:SGTC_2141|Compound:5621638|FD-Score:3.81|P-value:2.27E-4 ID:SGTC_2161|Compound:5662504|FD-Score:4.84|P-value:4.03E-6 ID:SGTC_2174|Compound:5790901|FD-Score:7.57|P-value:1.40E-12 ID:SGTC_2176|Compound:5809774|FD-Score:5.00|P-value:1.97E-6 ID:SGTC_2200|Compound:6600604|FD-Score:7.33|P-value:6.69E-12 ID:SGTC_2233|Compound:sulbentine|FD-Score:5.85|P-value:3.43E-8 ID:SGTC_2319|Compound:6033012|FD-Score:4.11|P-value:7.54E-5 ID:SGTC_2352|Compound:9027995|FD-Score:4.41|P-value:2.41E-5 ID:SGTC_2378|Compound:9074213|FD-Score:3.71|P-value:3.18E-4 ID:SGTC_2489|Compound:cantharidin|FD-Score:6.71|P-value:2.90E-10 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:-4.66|P-value:7.26E-6 ID:SGTC_2502|Compound:avocadyne acetate|FD-Score:6.09|P-value:9.56E-9 ID:SGTC_2534|Compound:helenine|FD-Score:4.17|P-value:6.10E-5 ID:SGTC_2544|Compound:sphondin|FD-Score:3.40|P-value:8.76E-4 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:-3.82|P-value:1.89E-4 ID:SGTC_2569|Compound:tetrandrine|FD-Score:-3.78|P-value:2.16E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:5.42|P-value:2.93E-7 ID:SGTC_2582|Compound:agaric acid|FD-Score:4.51|P-value:1.58E-5 ID:SGTC_2690|Compound:usnic acid|FD-Score:3.61|P-value:4.41E-4 ID:SGTC_2691|Compound:st077356|FD-Score:4.00|P-value:1.15E-4 ID:SGTC_2782|Compound:7736369|FD-Score:6.38|P-value:1.97E-9 ID:SGTC_2799|Compound:7812892|FD-Score:3.43|P-value:8.07E-4 ID:SGTC_2807|Compound:7945238|FD-Score:-3.52|P-value:5.28E-4 ID:SGTC_2816|Compound:7982706|FD-Score:3.78|P-value:2.47E-4 ID:SGTC_2841|Compound:9004761|FD-Score:4.04|P-value:9.80E-5 ID:SGTC_2845|Compound:9003024|FD-Score:4.39|P-value:2.60E-5 ID:SGTC_2852|Compound:9023854|FD-Score:-3.76|P-value:2.33E-4 ID:SGTC_2854|Compound:9024559|FD-Score:3.79|P-value:2.40E-4 ID:SGTC_2890|Compound:9046729|FD-Score:4.68|P-value:8.05E-6 ID:SGTC_2903|Compound:5923464|FD-Score:4.58|P-value:1.23E-5 ID:SGTC_2927|Compound:9011802|FD-Score:-5.18|P-value:7.20E-7 ID:SGTC_2928|Compound:9011484|FD-Score:-5.08|P-value:1.17E-6 ID:SGTC_3006|Compound:9075424|FD-Score:4.66|P-value:8.64E-6 ID:SGTC_3124|Compound:9127567|FD-Score:3.96|P-value:1.34E-4 ID:SGTC_3253|Compound:9135987|FD-Score:4.05|P-value:9.70E-5 ID:SGTC_3294|Compound:9122953|FD-Score:4.23|P-value:4.83E-5 ID:SGTC_18|Compound:0111-0177|FD-Score:4.45|P-value:2.07E-5 ID:SGTC_22|Compound:0964-0034|FD-Score:5.32|P-value:4.66E-7 ID:SGTC_67|Compound:0335-0847|FD-Score:4.11|P-value:7.68E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:7.33|P-value:6.57E-12 ID:SGTC_103|Compound:0844-0104|FD-Score:-3.41|P-value:7.37E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:4.09|P-value:8.08E-5 ID:SGTC_142|Compound:0335-0849|FD-Score:4.15|P-value:6.57E-5 ID:SGTC_149|Compound:3970-0822|FD-Score:3.47|P-value:6.93E-4 ID:SGTC_200|Compound:k038-0079|FD-Score:4.03|P-value:1.04E-4 ID:SGTC_210|Compound:3551-0445|FD-Score:5.54|P-value:1.63E-7 ID:SGTC_212|Compound:3807-4682|FD-Score:6.01|P-value:1.46E-8 ID:SGTC_214|Compound:4373-3496|FD-Score:3.76|P-value:2.64E-4 ID:SGTC_221|Compound:trifluoperazine|FD-Score:5.47|P-value:2.30E-7 ID:SGTC_229|Compound:benomyl|FD-Score:8.36|P-value:5.76E-15 ID:SGTC_286|Compound:k060-0067|FD-Score:4.56|P-value:1.29E-5 ID:SGTC_294|Compound:k038-0071|FD-Score:4.37|P-value:2.85E-5 ID:SGTC_310|Compound:1273-0058|FD-Score:-3.67|P-value:3.17E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:8.13|P-value:2.90E-14 ID:SGTC_367|Compound:0335-0881|FD-Score:5.53|P-value:1.69E-7 ID:SGTC_436|Compound:n,n-dimethylsphingosine|FD-Score:5.83|P-value:3.80E-8 ID:SGTC_442|Compound:cape|FD-Score:4.37|P-value:2.78E-5 ID:SGTC_444|Compound:curcumin|FD-Score:-3.54|P-value:4.90E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:5.51|P-value:1.89E-7 ID:SGTC_514|Compound:4466-0038|FD-Score:5.19|P-value:8.52E-7 ID:SGTC_580|Compound:1123-0028|FD-Score:5.17|P-value:9.48E-7 ID:SGTC_673|Compound:1082-0474|FD-Score:4.39|P-value:2.57E-5 ID:SGTC_771|Compound:0250-0039|FD-Score:5.93|P-value:2.24E-8 ID:SGTC_772|Compound:k072-0172|FD-Score:4.51|P-value:1.60E-5 ID:SGTC_794|Compound:k038-0031|FD-Score:4.27|P-value:4.19E-5 ID:SGTC_840|Compound:0245-0196|FD-Score:3.44|P-value:7.82E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:8.69|P-value:4.95E-16 ID:SGTC_912|Compound:3474-0017|FD-Score:5.33|P-value:4.38E-7 ID:SGTC_919|Compound:tnp00227|FD-Score:3.89|P-value:1.69E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:4.14|P-value:6.89E-5 ID:SGTC_1013|Compound:4112-3890|FD-Score:5.36|P-value:3.73E-7 ID:SGTC_1147|Compound:3809-1045|FD-Score:3.36|P-value:9.89E-4 ID:SGTC_1206|Compound:3978-0017|FD-Score:3.37|P-value:9.59E-4 ID:SGTC_1226|Compound:3909-7979|FD-Score:4.41|P-value:2.37E-5 ID:SGTC_1260|Compound:0700-1617|FD-Score:3.75|P-value:2.80E-4 ID:SGTC_1352|Compound:1496-0991|FD-Score:4.19|P-value:5.63E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:3.49|P-value:6.51E-4 ID:SGTC_1468|Compound:k284-1086|FD-Score:3.79|P-value:2.42E-4 ID:SGTC_1539|Compound:benzyladenosine|FD-Score:3.86|P-value:1.86E-4 ID:SGTC_1564|Compound:D-Arginine|FD-Score:4.14|P-value:6.91E-5 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:3.61|P-value:4.51E-4 ID:SGTC_1599|Compound:8-chlro-1-tetrahydronorharmanone|FD-Score:3.68|P-value:3.46E-4 ID:SGTC_1643|Compound:st009866|FD-Score:3.89|P-value:1.69E-4 ID:SGTC_1728|Compound:st035614|FD-Score:3.58|P-value:4.94E-4 ID:SGTC_1870|Compound:st057514|FD-Score:3.85|P-value:1.93E-4 ID:SGTC_1875|Compound:nocodazole|FD-Score:4.07|P-value:8.81E-5 ID:SGTC_1911|Compound:st060208|FD-Score:3.48|P-value:6.84E-4 ID:SGTC_2038|Compound:4100038|FD-Score:-3.54|P-value:4.93E-4 ID:SGTC_2044|Compound:5102272|FD-Score:3.62|P-value:4.31E-4 ID:SGTC_2060|Compound:5238662|FD-Score:4.63|P-value:9.90E-6 ID:SGTC_2061|Compound:5245884|FD-Score:5.03|P-value:1.79E-6 ID:SGTC_2141|Compound:5621638|FD-Score:3.81|P-value:2.27E-4 ID:SGTC_2161|Compound:5662504|FD-Score:4.84|P-value:4.03E-6 ID:SGTC_2174|Compound:5790901|FD-Score:7.57|P-value:1.40E-12 ID:SGTC_2176|Compound:5809774|FD-Score:5.00|P-value:1.97E-6 ID:SGTC_2200|Compound:6600604|FD-Score:7.33|P-value:6.69E-12 ID:SGTC_2233|Compound:sulbentine|FD-Score:5.85|P-value:3.43E-8 ID:SGTC_2319|Compound:6033012|FD-Score:4.11|P-value:7.54E-5 ID:SGTC_2352|Compound:9027995|FD-Score:4.41|P-value:2.41E-5 ID:SGTC_2378|Compound:9074213|FD-Score:3.71|P-value:3.18E-4 ID:SGTC_2489|Compound:cantharidin|FD-Score:6.71|P-value:2.90E-10 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:-4.66|P-value:7.26E-6 ID:SGTC_2502|Compound:avocadyne acetate|FD-Score:6.09|P-value:9.56E-9 ID:SGTC_2534|Compound:helenine|FD-Score:4.17|P-value:6.10E-5 ID:SGTC_2544|Compound:sphondin|FD-Score:3.40|P-value:8.76E-4 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:-3.82|P-value:1.89E-4 ID:SGTC_2569|Compound:tetrandrine|FD-Score:-3.78|P-value:2.16E-4 ID:SGTC_2573|Compound:2',4'-dihydroxychalcone|FD-Score:5.42|P-value:2.93E-7 ID:SGTC_2582|Compound:agaric acid|FD-Score:4.51|P-value:1.58E-5 ID:SGTC_2690|Compound:usnic acid|FD-Score:3.61|P-value:4.41E-4 ID:SGTC_2691|Compound:st077356|FD-Score:4.00|P-value:1.15E-4 ID:SGTC_2782|Compound:7736369|FD-Score:6.38|P-value:1.97E-9 ID:SGTC_2799|Compound:7812892|FD-Score:3.43|P-value:8.07E-4 ID:SGTC_2807|Compound:7945238|FD-Score:-3.52|P-value:5.28E-4 ID:SGTC_2816|Compound:7982706|FD-Score:3.78|P-value:2.47E-4 ID:SGTC_2841|Compound:9004761|FD-Score:4.04|P-value:9.80E-5 ID:SGTC_2845|Compound:9003024|FD-Score:4.39|P-value:2.60E-5 ID:SGTC_2852|Compound:9023854|FD-Score:-3.76|P-value:2.33E-4 ID:SGTC_2854|Compound:9024559|FD-Score:3.79|P-value:2.40E-4 ID:SGTC_2890|Compound:9046729|FD-Score:4.68|P-value:8.05E-6 ID:SGTC_2903|Compound:5923464|FD-Score:4.58|P-value:1.23E-5 ID:SGTC_2927|Compound:9011802|FD-Score:-5.18|P-value:7.20E-7 ID:SGTC_2928|Compound:9011484|FD-Score:-5.08|P-value:1.17E-6 ID:SGTC_3006|Compound:9075424|FD-Score:4.66|P-value:8.64E-6 ID:SGTC_3124|Compound:9127567|FD-Score:3.96|P-value:1.34E-4 ID:SGTC_3253|Compound:9135987|FD-Score:4.05|P-value:9.70E-5 ID:SGTC_3294|Compound:9122953|FD-Score:4.23|P-value:4.83E-5

Top fitness defect scores for YOL012C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_897 1000-0139 8.69 31.4 µM 4.95E-16 8 1.81E-18
2 SGTC_229 benomyl 8.36 22.9 µM 5.76E-15 tubulin folding & SWR complex 13 3.16E-17
3 SGTC_351 caspofungin 8.13 25.0 nM 2.90E-14 cell wall 16 2.08E-16
4 SGTC_2174 5790901 7.57 200.0 µM 1.40E-12 tubulin folding & SWR complex 13 1.92E-14
5 SGTC_86 0417-1630 7.33 471.9 µM 6.57E-12 ubiquinone biosynthesis & proteasome 66 1.16E-13
6 SGTC_2200 6600604 7.33 21.9 µM 6.69E-12 tubulin folding & SWR complex 19 1.19E-13
7 SGTC_2489 cantharidin 6.71 73.4 µM 2.90E-10 cell wall signaling 5 9.62E-12
8 SGTC_2782 7736369 6.38 71.4 µM 1.97E-9 4 8.97E-11
9 SGTC_2502 avocadyne acetate 6.09 18.6 µM 9.56E-9 7 5.66E-10
10 SGTC_212 3807-4682 6.01 38.8 µM 1.46E-8 tubulin folding & SWR complex 27 9.26E-10
11 SGTC_771 0250-0039 5.93 27.3 µM 2.24E-8 5 1.53E-9
12 SGTC_2233 sulbentine 5.85 40.4 µM 3.43E-8 26 2.51E-9
13 SGTC_436 n,n-dimethylsphingosine 5.83 3.3 µM 3.80E-8 3 2.83E-9
14 SGTC_210 3551-0445 5.54 56.8 µM 1.63E-7 29 1.55E-8
15 SGTC_367 0335-0881 5.53 7.1 µM 1.69E-7 ubiquinone biosynthesis & proteasome 28 1.61E-8
16 SGTC_445 e6 berbamine 5.51 66.0 µM 1.89E-7 NEO1-PIK1 41 1.83E-8
17 SGTC_221 trifluoperazine 5.47 10.3 µM 2.30E-7 NEO1-PIK1 146 2.31E-8
18 SGTC_2573 2',4'-dihydroxychalcone 5.42 15.0 µM 2.93E-7 20 3.05E-8
19 SGTC_1013 4112-3890 5.36 241.0 µM 3.73E-7 TSC3-RPN4 11 4.05E-8
20 SGTC_912 3474-0017 5.33 2.2 µM 4.38E-7 7 4.87E-8

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.471 4.74E-185 YLR085C ARP6 hom Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A
0.446 1.47E-163 YDR485C VPS72 hom Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting
0.416 1.56E-140 YDR334W SWR1 hom Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A
0.415 1.38E-139 YAL011W SWC3 hom Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae
0.408 2.13E-134 YML041C VPS71 hom Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting
0.387 1.86E-120 YBR231C SWC5 hom Component of the SWR1 complex; complex exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; protein abundance increases in response to DNA replication stress
0.360 2.49E-103 YML124C TUB3 hom Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication
0.357 3.58E-101 YER007W PAC2 hom Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl
0.288 5.39E-65 YOR349W CIN1 hom Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
0.254 1.85E-50 YPL241C CIN2 hom GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2
0.186 1.73E-27 YOR254C SEC63 het Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
0.180 7.86E-26 YJL168C SET2 hom Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36, which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p
0.179 1.75E-25 YMR110C HFD1 hom Hexadecenal dehydrogenase; involved in the conversion of sphingosine 1-phosphate breakdown product hexadecenal to hexadecenoic acid; located in the mitochondrial outer membrane and also in lipid particles; has similarity to ALDH3A2, a human fatty aldehyde dehydrogenase (FALDH) mutated in Sjogren-Larsson syndrome, a neurocutaneous disorder
0.171 1.99E-23 YJL169W_d YJL169W_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL168C/SET2
0.170 4.78E-23 YML034C-A_d YML034C-A_d hom Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data