YOR157C / PUP1

Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z

Zygosity: Heterozygous strain
fixedexpanded
Profile for YOR157C / PUP1

Click on Significant Values for Screen Details ID:SGTC_64|Compound:000l-0018|FD-Score:4.57|P-value:4.65E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:4.02|P-value:2.90E-4 ID:SGTC_88|Compound:0180-0332|FD-Score:5.40|P-value:1.87E-6 ID:SGTC_137|Compound:0438-0332|FD-Score:3.83|P-value:5.23E-4 ID:SGTC_167|Compound:3672-0051|FD-Score:7.08|P-value:6.30E-10 ID:SGTC_168|Compound:3970-0862|FD-Score:4.99|P-value:9.61E-6 ID:SGTC_171|Compound:k064-0041|FD-Score:-4.37|P-value:7.81E-5 ID:SGTC_237|Compound:nikkomycin|FD-Score:4.27|P-value:1.29E-4 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:3.67|P-value:8.52E-4 ID:SGTC_262|Compound:fenpropimorph|FD-Score:3.63|P-value:9.66E-4 ID:SGTC_284|Compound:0988-0104|FD-Score:-9.13|P-value:1.69E-15 ID:SGTC_309|Compound:k408-0051|FD-Score:-3.73|P-value:6.15E-4 ID:SGTC_335|Compound:4077-0256|FD-Score:-4.65|P-value:2.94E-5 ID:SGTC_350|Compound:k064-0020|FD-Score:-4.18|P-value:1.47E-4 ID:SGTC_372|Compound:0155-0182|FD-Score:-6.68|P-value:3.90E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:-4.94|P-value:9.60E-6 ID:SGTC_393|Compound:acivicin|FD-Score:-4.07|P-value:2.13E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:-8.43|P-value:1.76E-13 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-4.87|P-value:1.28E-5 ID:SGTC_490|Compound:phenamil|FD-Score:-7.53|P-value:4.10E-11 ID:SGTC_699|Compound:0375-0592|FD-Score:3.73|P-value:7.13E-4 ID:SGTC_710|Compound:3448-4187|FD-Score:6.10|P-value:8.51E-8 ID:SGTC_712|Compound:r015-0009|FD-Score:4.62|P-value:3.76E-5 ID:SGTC_816|Compound:0325-0417|FD-Score:-5.24|P-value:2.95E-6 ID:SGTC_817|Compound:1391-0715|FD-Score:-3.65|P-value:7.93E-4 ID:SGTC_818|Compound:4072-2707|FD-Score:-4.76|P-value:1.92E-5 ID:SGTC_893|Compound:0958-0369|FD-Score:-3.90|P-value:3.72E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:5.03|P-value:8.26E-6 ID:SGTC_910|Compound:3454-3003|FD-Score:3.84|P-value:5.14E-4 ID:SGTC_917|Compound:harmaline|FD-Score:4.77|P-value:2.18E-5 ID:SGTC_936|Compound:3005-4620|FD-Score:-3.99|P-value:2.72E-4 ID:SGTC_1000|Compound:4048-0884|FD-Score:7.80|P-value:1.13E-11 ID:SGTC_1001|Compound:4048-4355|FD-Score:5.59|P-value:8.24E-7 ID:SGTC_1005|Compound:4092-0690|FD-Score:6.05|P-value:1.06E-7 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.14|P-value:1.69E-4 ID:SGTC_1048|Compound:3161-0300|FD-Score:5.46|P-value:1.44E-6 ID:SGTC_1051|Compound:3253-3903|FD-Score:3.81|P-value:5.55E-4 ID:SGTC_1055|Compound:3448-0672|FD-Score:3.82|P-value:5.47E-4 ID:SGTC_1083|Compound:didemethylchlorpromazine sulfoxide|FD-Score:7.44|P-value:8.71E-11 ID:SGTC_1239|Compound:0337-0584|FD-Score:4.98|P-value:1.02E-5 ID:SGTC_1425|Compound:4048-4433|FD-Score:5.39|P-value:1.98E-6 ID:SGTC_1521|Compound:st012942|FD-Score:4.03|P-value:2.83E-4 ID:SGTC_1547|Compound:harmine|FD-Score:3.89|P-value:4.42E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:4.20|P-value:1.63E-4 ID:SGTC_1615|Compound:st002656|FD-Score:5.04|P-value:8.06E-6 ID:SGTC_1623|Compound:st003709|FD-Score:3.65|P-value:8.98E-4 ID:SGTC_1675|Compound:st018485|FD-Score:4.13|P-value:2.04E-4 ID:SGTC_1750|Compound:st081859|FD-Score:4.38|P-value:9.03E-5 ID:SGTC_1815|Compound:st051655|FD-Score:3.75|P-value:6.66E-4 ID:SGTC_1825|Compound:st052143|FD-Score:4.90|P-value:1.33E-5 ID:SGTC_1829|Compound:berberine|FD-Score:4.49|P-value:6.17E-5 ID:SGTC_1830|Compound:st055982|FD-Score:4.98|P-value:9.92E-6 ID:SGTC_1853|Compound:st056710|FD-Score:4.66|P-value:3.26E-5 ID:SGTC_1873|Compound:rapamycin|FD-Score:6.39|P-value:2.19E-8 ID:SGTC_1941|Compound:st076221|FD-Score:-3.74|P-value:6.04E-4 ID:SGTC_1952|Compound:st077036|FD-Score:-4.59|P-value:3.60E-5 ID:SGTC_1995|Compound:st072814|FD-Score:4.66|P-value:3.30E-5 ID:SGTC_2006|Compound:4011487|FD-Score:7.23|P-value:2.74E-10 ID:SGTC_2012|Compound:4023501|FD-Score:4.23|P-value:1.49E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:4.86|P-value:1.57E-5 ID:SGTC_2269|Compound:7935389|FD-Score:3.73|P-value:7.14E-4 ID:SGTC_2271|Compound:7849410|FD-Score:7.12|P-value:5.13E-10 ID:SGTC_2340|Compound:7987427|FD-Score:5.11|P-value:5.92E-6 ID:SGTC_2350|Compound:9023895|FD-Score:5.73|P-value:4.54E-7 ID:SGTC_2461|Compound:5755302|FD-Score:3.76|P-value:6.44E-4 ID:SGTC_2497|Compound:7-hydroxyflavone|FD-Score:4.67|P-value:3.18E-5 ID:SGTC_2525|Compound:harmine|FD-Score:3.95|P-value:3.63E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.84|P-value:2.85E-7 ID:SGTC_2583|Compound:asiatic acid|FD-Score:-4.57|P-value:3.84E-5 ID:SGTC_2587|Compound:piperic acid|FD-Score:3.84|P-value:5.15E-4 ID:SGTC_2614|Compound:arthonioic acid|FD-Score:-4.99|P-value:7.99E-6 ID:SGTC_2639|Compound:lactacystin|FD-Score:6.41|P-value:1.90E-8 ID:SGTC_2671|Compound:danthron|FD-Score:4.47|P-value:6.52E-5 ID:SGTC_2704|Compound:st078022|FD-Score:-4.46|P-value:5.68E-5 ID:SGTC_2709|Compound:st078560|FD-Score:8.80|P-value:2.11E-14 ID:SGTC_2743|Compound:auranofin|FD-Score:4.38|P-value:8.86E-5 ID:SGTC_2753|Compound:fluvastatin|FD-Score:6.50|P-value:1.28E-8 ID:SGTC_2765|Compound:myclobutanil|FD-Score:3.66|P-value:8.83E-4 ID:SGTC_2797|Compound:7859098|FD-Score:4.72|P-value:2.67E-5 ID:SGTC_2828|Compound:7998861|FD-Score:3.67|P-value:8.50E-4 ID:SGTC_2935|Compound:9038016|FD-Score:3.63|P-value:9.48E-4 ID:SGTC_2968|Compound:9090663|FD-Score:-4.47|P-value:5.59E-5 ID:SGTC_2971|Compound:9092186|FD-Score:4.88|P-value:1.48E-5 ID:SGTC_2980|Compound:9014342|FD-Score:-5.46|P-value:1.17E-6 ID:SGTC_2981|Compound:9013952|FD-Score:-6.04|P-value:8.95E-8 ID:SGTC_3062|Compound:9077494|FD-Score:-4.32|P-value:9.21E-5 ID:SGTC_3087|Compound:9117406|FD-Score:3.99|P-value:3.20E-4 ID:SGTC_3096|Compound:9117468|FD-Score:4.47|P-value:6.61E-5 ID:SGTC_3175|Compound:9106517|FD-Score:3.72|P-value:7.43E-4 ID:SGTC_3197|Compound:9113331|FD-Score:4.09|P-value:2.37E-4 ID:SGTC_3282|Compound:9108498|FD-Score:5.72|P-value:4.69E-7 ID:SGTC_3288|Compound:9119690|FD-Score:5.05|P-value:7.48E-6 ID:SGTC_3293|Compound:9120939|FD-Score:4.73|P-value:2.59E-5 ID:SGTC_64|Compound:000l-0018|FD-Score:4.57|P-value:4.65E-5 ID:SGTC_86|Compound:0417-1630|FD-Score:4.02|P-value:2.90E-4 ID:SGTC_88|Compound:0180-0332|FD-Score:5.40|P-value:1.87E-6 ID:SGTC_137|Compound:0438-0332|FD-Score:3.83|P-value:5.23E-4 ID:SGTC_167|Compound:3672-0051|FD-Score:7.08|P-value:6.30E-10 ID:SGTC_168|Compound:3970-0862|FD-Score:4.99|P-value:9.61E-6 ID:SGTC_171|Compound:k064-0041|FD-Score:-4.37|P-value:7.81E-5 ID:SGTC_237|Compound:nikkomycin|FD-Score:4.27|P-value:1.29E-4 ID:SGTC_241|Compound:5hr heat shock (37°C) + cantharidin|FD-Score:3.67|P-value:8.52E-4 ID:SGTC_262|Compound:fenpropimorph|FD-Score:3.63|P-value:9.66E-4 ID:SGTC_284|Compound:0988-0104|FD-Score:-9.13|P-value:1.69E-15 ID:SGTC_309|Compound:k408-0051|FD-Score:-3.73|P-value:6.15E-4 ID:SGTC_335|Compound:4077-0256|FD-Score:-4.65|P-value:2.94E-5 ID:SGTC_350|Compound:k064-0020|FD-Score:-4.18|P-value:1.47E-4 ID:SGTC_372|Compound:0155-0182|FD-Score:-6.68|P-value:3.90E-9 ID:SGTC_383|Compound:2324-0395|FD-Score:-4.94|P-value:9.60E-6 ID:SGTC_393|Compound:acivicin|FD-Score:-4.07|P-value:2.13E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:-8.43|P-value:1.76E-13 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-4.87|P-value:1.28E-5 ID:SGTC_490|Compound:phenamil|FD-Score:-7.53|P-value:4.10E-11 ID:SGTC_699|Compound:0375-0592|FD-Score:3.73|P-value:7.13E-4 ID:SGTC_710|Compound:3448-4187|FD-Score:6.10|P-value:8.51E-8 ID:SGTC_712|Compound:r015-0009|FD-Score:4.62|P-value:3.76E-5 ID:SGTC_816|Compound:0325-0417|FD-Score:-5.24|P-value:2.95E-6 ID:SGTC_817|Compound:1391-0715|FD-Score:-3.65|P-value:7.93E-4 ID:SGTC_818|Compound:4072-2707|FD-Score:-4.76|P-value:1.92E-5 ID:SGTC_893|Compound:0958-0369|FD-Score:-3.90|P-value:3.72E-4 ID:SGTC_897|Compound:1000-0139|FD-Score:5.03|P-value:8.26E-6 ID:SGTC_910|Compound:3454-3003|FD-Score:3.84|P-value:5.14E-4 ID:SGTC_917|Compound:harmaline|FD-Score:4.77|P-value:2.18E-5 ID:SGTC_936|Compound:3005-4620|FD-Score:-3.99|P-value:2.72E-4 ID:SGTC_1000|Compound:4048-0884|FD-Score:7.80|P-value:1.13E-11 ID:SGTC_1001|Compound:4048-4355|FD-Score:5.59|P-value:8.24E-7 ID:SGTC_1005|Compound:4092-0690|FD-Score:6.05|P-value:1.06E-7 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.14|P-value:1.69E-4 ID:SGTC_1048|Compound:3161-0300|FD-Score:5.46|P-value:1.44E-6 ID:SGTC_1051|Compound:3253-3903|FD-Score:3.81|P-value:5.55E-4 ID:SGTC_1055|Compound:3448-0672|FD-Score:3.82|P-value:5.47E-4 ID:SGTC_1083|Compound:didemethylchlorpromazine sulfoxide|FD-Score:7.44|P-value:8.71E-11 ID:SGTC_1239|Compound:0337-0584|FD-Score:4.98|P-value:1.02E-5 ID:SGTC_1425|Compound:4048-4433|FD-Score:5.39|P-value:1.98E-6 ID:SGTC_1521|Compound:st012942|FD-Score:4.03|P-value:2.83E-4 ID:SGTC_1547|Compound:harmine|FD-Score:3.89|P-value:4.42E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:4.20|P-value:1.63E-4 ID:SGTC_1615|Compound:st002656|FD-Score:5.04|P-value:8.06E-6 ID:SGTC_1623|Compound:st003709|FD-Score:3.65|P-value:8.98E-4 ID:SGTC_1675|Compound:st018485|FD-Score:4.13|P-value:2.04E-4 ID:SGTC_1750|Compound:st081859|FD-Score:4.38|P-value:9.03E-5 ID:SGTC_1815|Compound:st051655|FD-Score:3.75|P-value:6.66E-4 ID:SGTC_1825|Compound:st052143|FD-Score:4.90|P-value:1.33E-5 ID:SGTC_1829|Compound:berberine|FD-Score:4.49|P-value:6.17E-5 ID:SGTC_1830|Compound:st055982|FD-Score:4.98|P-value:9.92E-6 ID:SGTC_1853|Compound:st056710|FD-Score:4.66|P-value:3.26E-5 ID:SGTC_1873|Compound:rapamycin|FD-Score:6.39|P-value:2.19E-8 ID:SGTC_1941|Compound:st076221|FD-Score:-3.74|P-value:6.04E-4 ID:SGTC_1952|Compound:st077036|FD-Score:-4.59|P-value:3.60E-5 ID:SGTC_1995|Compound:st072814|FD-Score:4.66|P-value:3.30E-5 ID:SGTC_2006|Compound:4011487|FD-Score:7.23|P-value:2.74E-10 ID:SGTC_2012|Compound:4023501|FD-Score:4.23|P-value:1.49E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:4.86|P-value:1.57E-5 ID:SGTC_2269|Compound:7935389|FD-Score:3.73|P-value:7.14E-4 ID:SGTC_2271|Compound:7849410|FD-Score:7.12|P-value:5.13E-10 ID:SGTC_2340|Compound:7987427|FD-Score:5.11|P-value:5.92E-6 ID:SGTC_2350|Compound:9023895|FD-Score:5.73|P-value:4.54E-7 ID:SGTC_2461|Compound:5755302|FD-Score:3.76|P-value:6.44E-4 ID:SGTC_2497|Compound:7-hydroxyflavone|FD-Score:4.67|P-value:3.18E-5 ID:SGTC_2525|Compound:harmine|FD-Score:3.95|P-value:3.63E-4 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:5.84|P-value:2.85E-7 ID:SGTC_2583|Compound:asiatic acid|FD-Score:-4.57|P-value:3.84E-5 ID:SGTC_2587|Compound:piperic acid|FD-Score:3.84|P-value:5.15E-4 ID:SGTC_2614|Compound:arthonioic acid|FD-Score:-4.99|P-value:7.99E-6 ID:SGTC_2639|Compound:lactacystin|FD-Score:6.41|P-value:1.90E-8 ID:SGTC_2671|Compound:danthron|FD-Score:4.47|P-value:6.52E-5 ID:SGTC_2704|Compound:st078022|FD-Score:-4.46|P-value:5.68E-5 ID:SGTC_2709|Compound:st078560|FD-Score:8.80|P-value:2.11E-14 ID:SGTC_2743|Compound:auranofin|FD-Score:4.38|P-value:8.86E-5 ID:SGTC_2753|Compound:fluvastatin|FD-Score:6.50|P-value:1.28E-8 ID:SGTC_2765|Compound:myclobutanil|FD-Score:3.66|P-value:8.83E-4 ID:SGTC_2797|Compound:7859098|FD-Score:4.72|P-value:2.67E-5 ID:SGTC_2828|Compound:7998861|FD-Score:3.67|P-value:8.50E-4 ID:SGTC_2935|Compound:9038016|FD-Score:3.63|P-value:9.48E-4 ID:SGTC_2968|Compound:9090663|FD-Score:-4.47|P-value:5.59E-5 ID:SGTC_2971|Compound:9092186|FD-Score:4.88|P-value:1.48E-5 ID:SGTC_2980|Compound:9014342|FD-Score:-5.46|P-value:1.17E-6 ID:SGTC_2981|Compound:9013952|FD-Score:-6.04|P-value:8.95E-8 ID:SGTC_3062|Compound:9077494|FD-Score:-4.32|P-value:9.21E-5 ID:SGTC_3087|Compound:9117406|FD-Score:3.99|P-value:3.20E-4 ID:SGTC_3096|Compound:9117468|FD-Score:4.47|P-value:6.61E-5 ID:SGTC_3175|Compound:9106517|FD-Score:3.72|P-value:7.43E-4 ID:SGTC_3197|Compound:9113331|FD-Score:4.09|P-value:2.37E-4 ID:SGTC_3282|Compound:9108498|FD-Score:5.72|P-value:4.69E-7 ID:SGTC_3288|Compound:9119690|FD-Score:5.05|P-value:7.48E-6 ID:SGTC_3293|Compound:9120939|FD-Score:4.73|P-value:2.59E-5

Top fitness defect scores for YOR157C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_2709 st078560 8.80 56.0 µM 2.11E-14 1 6.72E-19 2.68
2 SGTC_1000 4048-0884 7.80 8.7 µM 1.13E-11 copper-dependent oxidative stress 2 3.19E-15 1.83
3 SGTC_1083 didemethylchlorpromazine sulfoxide 7.44 707.4 nM 8.71E-11 redox potentiating 11 5.02E-14 0.94
4 SGTC_2006 4011487 7.23 200.0 µM 2.74E-10 endomembrane recycling 7 2.35E-13 0.33
5 SGTC_2271 7849410 7.12 118.6 µM 5.13E-10 1 5.46E-13 2.38
6 SGTC_167 3672-0051 7.08 66.2 µM 6.30E-10 1 7.20E-13 1.20
7 SGTC_2753 fluvastatin 6.50 17.1 µM 1.28E-8 azole & statin 4 4.13E-11 1.24
8 SGTC_2639 lactacystin 6.41 53.0 µM 1.90E-8 1 7.06E-11 0.65
9 SGTC_1873 rapamycin 6.39 2.0 nM 2.19E-8 9 8.53E-11 0.15
10 SGTC_710 3448-4187 6.10 58.0 µM 8.51E-8 fatty acid desaturase (OLE1) 3 5.30E-10 0.94
11 SGTC_1005 4092-0690 6.05 4.4 µM 1.06E-7 plasma membrane duress 1 7.09E-10 0.77
12 SGTC_2567 aureobasidin a 5.84 60.0 nM 2.85E-7 19 2.68E-9 0.08
13 SGTC_2350 9023895 5.73 38.9 µM 4.54E-7 ergosterol biosynthesis 3 5.02E-9 0.67
14 SGTC_3282 9108498 5.72 15.5 µM 4.69E-7 6 5.24E-9 0.81
15 SGTC_1001 4048-4355 5.59 44.4 µM 8.24E-7 copper-dependent oxidative stress 4 1.12E-8 0.14
16 SGTC_1048 3161-0300 5.46 24.5 µM 1.44E-6 2 2.36E-8 0.81
17 SGTC_88 0180-0332 5.40 8.7 µM 1.87E-6 2 3.36E-8 0.72
18 SGTC_1425 4048-4433 5.39 7.3 µM 1.98E-6 copper-dependent oxidative stress 1 3.62E-8 0.60
19 SGTC_2340 7987427 5.11 183.4 µM 5.92E-6 3 1.58E-7 0.21
20 SGTC_3288 9119690 5.05 36.2 µM 7.48E-6 15 2.16E-7 0.01

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.295 2.08E-68 YOR319W HSH49 het U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
0.251 2.28E-49 YHR007C ERG11 het Lanosterol 14-alpha-demethylase; catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p
0.167 1.85E-22 YOR340C RPA43 het RNA polymerase I subunit A43
0.154 2.48E-19 YGL116W CDC20 het Activator of anaphase-promoting complex/cyclosome (APC/C); APC/C is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; cell-cycle regulated; potential Cdc28p substrate; relative distribution to the nucleus increases upon DNA replication stress
0.131 2.87E-14 YOR224C RPB8 het RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III
0.130 3.71E-14 YCR093W CDC39 het Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
0.130 5.65E-14 YMR314W PRE5 het Alpha 6 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress
0.126 2.72E-13 YML031W NDC1 het Subunit of the transmembrane ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport, NPC biogenesis and spindle pole body duplication; homologous to human NDC1
0.124 4.98E-13 YPL251W_d YPL251W_d het Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 5' end of the verified, essential gene YAH1/YPL252C
0.112 7.60E-11 YOR362C PRE10 het Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress
0.111 1.14E-10 YGL011C SCL1 het Alpha 1 subunit of the 20S proteasome involved in the degradation of ubiquitinated substrates; 20S proteasome is the core complex of the 26S proteasome; essential for growth; detected in the mitochondria
0.111 1.16E-10 YOL038W PRE6 het Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress
0.111 1.37E-10 YPL237W SUI3 het Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding
0.111 1.47E-10 YER094C PUP3 het Beta 3 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10
0.108 3.41E-10 YMR268C PRP24 het Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling