YPL093W / NOG1

Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins

Zygosity: Heterozygous strain
fixedexpanded
Profile for YPL093W / NOG1

Click on Significant Values for Screen Details ID:SGTC_36|Compound:0335-0881|FD-Score:3.87|P-value:3.85E-4 ID:SGTC_66|Compound:0109-0187|FD-Score:5.14|P-value:3.99E-6 ID:SGTC_79|Compound:0052-0007|FD-Score:-3.75|P-value:5.24E-4 ID:SGTC_97|Compound:0535-0701|FD-Score:11.40|P-value:2.08E-23 ID:SGTC_115|Compound:0527-0192|FD-Score:3.73|P-value:6.06E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:4.72|P-value:2.10E-5 ID:SGTC_134|Compound:0269-0018|FD-Score:6.35|P-value:1.74E-8 ID:SGTC_136|Compound:0097-0015|FD-Score:4.80|P-value:1.53E-5 ID:SGTC_176|Compound:1486-1328|FD-Score:3.90|P-value:3.51E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:3.60|P-value:8.86E-4 ID:SGTC_348|Compound:k064-0012|FD-Score:4.11|P-value:1.77E-4 ID:SGTC_437|Compound:s-farnesyl-l-cysteine methyl ester|FD-Score:4.29|P-value:9.92E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:-3.75|P-value:5.34E-4 ID:SGTC_464|Compound:bw-b 70c|FD-Score:4.14|P-value:1.65E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-4.71|P-value:1.96E-5 ID:SGTC_598|Compound:3937-0236|FD-Score:3.84|P-value:4.23E-4 ID:SGTC_776|Compound:4476-4378|FD-Score:3.92|P-value:3.30E-4 ID:SGTC_832|Compound:4083-0019|FD-Score:3.58|P-value:9.36E-4 ID:SGTC_922|Compound:1866-0035|FD-Score:-4.15|P-value:1.47E-4 ID:SGTC_927|Compound:2425-1185|FD-Score:4.82|P-value:1.41E-5 ID:SGTC_939|Compound:1165-0479|FD-Score:4.65|P-value:2.65E-5 ID:SGTC_976|Compound:1348-1067|FD-Score:4.71|P-value:2.12E-5 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.08|P-value:1.82E-4 ID:SGTC_1070|Compound:indatraline|FD-Score:3.66|P-value:7.44E-4 ID:SGTC_1074|Compound:carmofur|FD-Score:3.66|P-value:7.35E-4 ID:SGTC_1080|Compound:nisoldipine|FD-Score:-4.40|P-value:6.12E-5 ID:SGTC_1085|Compound:doxorubicin|FD-Score:-4.42|P-value:5.68E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:4.97|P-value:7.95E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:3.76|P-value:5.57E-4 ID:SGTC_1240|Compound:0356-0016|FD-Score:-6.11|P-value:4.97E-8 ID:SGTC_1246|Compound:0422-0085|FD-Score:6.22|P-value:3.27E-8 ID:SGTC_1381|Compound:2324-0066|FD-Score:4.37|P-value:7.48E-5 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:3.88|P-value:3.82E-4 ID:SGTC_1542|Compound:7-hydroxy-3'-methoxyflavone|FD-Score:4.12|P-value:1.76E-4 ID:SGTC_1643|Compound:st009866|FD-Score:-3.85|P-value:3.83E-4 ID:SGTC_1776|Compound:st049249|FD-Score:3.57|P-value:9.80E-4 ID:SGTC_1786|Compound:berberine|FD-Score:3.60|P-value:8.79E-4 ID:SGTC_1827|Compound:berberine|FD-Score:6.07|P-value:6.54E-8 ID:SGTC_1829|Compound:berberine|FD-Score:9.66|P-value:2.21E-17 ID:SGTC_2002|Compound:4023503|FD-Score:3.93|P-value:3.18E-4 ID:SGTC_2015|Compound:5119600|FD-Score:4.58|P-value:3.54E-5 ID:SGTC_2036|Compound:5160441|FD-Score:-4.57|P-value:3.26E-5 ID:SGTC_2041|Compound:5107442|FD-Score:-4.26|P-value:1.00E-4 ID:SGTC_2047|Compound:4141938|FD-Score:3.60|P-value:9.02E-4 ID:SGTC_2050|Compound:5263056|FD-Score:4.94|P-value:8.94E-6 ID:SGTC_2100|Compound:5377183|FD-Score:5.85|P-value:1.82E-7 ID:SGTC_2104|Compound:5389443|FD-Score:4.05|P-value:2.17E-4 ID:SGTC_2111|Compound:5486399|FD-Score:-3.90|P-value:3.29E-4 ID:SGTC_2121|Compound:5257820|FD-Score:6.21|P-value:3.45E-8 ID:SGTC_2178|Compound:5812956|FD-Score:3.99|P-value:2.66E-4 ID:SGTC_2297|Compound:7971671|FD-Score:-4.08|P-value:1.81E-4 ID:SGTC_2300|Compound:7976697|FD-Score:-4.62|P-value:2.79E-5 ID:SGTC_2302|Compound:7771753|FD-Score:5.34|P-value:1.73E-6 ID:SGTC_2344|Compound:7990960|FD-Score:-3.98|P-value:2.54E-4 ID:SGTC_2348|Compound:9022543|FD-Score:-4.06|P-value:1.95E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-4.66|P-value:2.33E-5 ID:SGTC_2376|Compound:9072922|FD-Score:-5.45|P-value:9.84E-7 ID:SGTC_2377|Compound:9073351|FD-Score:-3.82|P-value:4.24E-4 ID:SGTC_2382|Compound:9035899|FD-Score:4.25|P-value:1.14E-4 ID:SGTC_2511|Compound:berberine|FD-Score:3.60|P-value:8.91E-4 ID:SGTC_2530|Compound:3-alpha-hydroxy-4,4-bisnor-8,11,13-podocarpatriene|FD-Score:3.85|P-value:4.16E-4 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:4.82|P-value:1.40E-5 ID:SGTC_2640|Compound:pentamidine|FD-Score:-3.90|P-value:3.28E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:4.22|P-value:1.24E-4 ID:SGTC_2664|Compound:lyso-paf C-16|FD-Score:4.99|P-value:7.33E-6 ID:SGTC_2698|Compound:st077697|FD-Score:4.28|P-value:9.94E-5 ID:SGTC_2757|Compound:clomiphene|FD-Score:4.56|P-value:3.73E-5 ID:SGTC_2782|Compound:7736369|FD-Score:5.61|P-value:5.47E-7 ID:SGTC_2785|Compound:7756463|FD-Score:5.26|P-value:2.44E-6 ID:SGTC_2792|Compound:7535235|FD-Score:3.91|P-value:3.43E-4 ID:SGTC_2834|Compound:9001755|FD-Score:3.67|P-value:7.27E-4 ID:SGTC_2880|Compound:9042983|FD-Score:3.68|P-value:7.00E-4 ID:SGTC_2887|Compound:9044784|FD-Score:3.82|P-value:4.60E-4 ID:SGTC_2893|Compound:9048488|FD-Score:4.24|P-value:1.16E-4 ID:SGTC_2928|Compound:9011484|FD-Score:-3.64|P-value:7.36E-4 ID:SGTC_2948|Compound:9070189|FD-Score:-3.94|P-value:2.88E-4 ID:SGTC_2993|Compound:9054257|FD-Score:3.79|P-value:4.99E-4 ID:SGTC_3065|Compound:9113888|FD-Score:-3.61|P-value:8.02E-4 ID:SGTC_3071|Compound:9117417|FD-Score:4.18|P-value:1.44E-4 ID:SGTC_3081|Compound:9117243|FD-Score:3.83|P-value:4.38E-4 ID:SGTC_3108|Compound:9121785|FD-Score:-4.76|P-value:1.62E-5 ID:SGTC_3116|Compound:9124943|FD-Score:4.32|P-value:8.82E-5 ID:SGTC_3126|Compound:9127922|FD-Score:7.43|P-value:5.16E-11 ID:SGTC_3132|Compound:9126706|FD-Score:-8.06|P-value:1.05E-12 ID:SGTC_3144|Compound:9087057|FD-Score:4.53|P-value:4.15E-5 ID:SGTC_3145|Compound:9085516|FD-Score:7.73|P-value:8.96E-12 ID:SGTC_3194|Compound:9111903|FD-Score:4.79|P-value:1.59E-5 ID:SGTC_3197|Compound:9113331|FD-Score:-5.41|P-value:1.16E-6 ID:SGTC_3308|Compound:9128332|FD-Score:-6.85|P-value:1.13E-9 ID:SGTC_36|Compound:0335-0881|FD-Score:3.87|P-value:3.85E-4 ID:SGTC_66|Compound:0109-0187|FD-Score:5.14|P-value:3.99E-6 ID:SGTC_79|Compound:0052-0007|FD-Score:-3.75|P-value:5.24E-4 ID:SGTC_97|Compound:0535-0701|FD-Score:11.40|P-value:2.08E-23 ID:SGTC_115|Compound:0527-0192|FD-Score:3.73|P-value:6.06E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:4.72|P-value:2.10E-5 ID:SGTC_134|Compound:0269-0018|FD-Score:6.35|P-value:1.74E-8 ID:SGTC_136|Compound:0097-0015|FD-Score:4.80|P-value:1.53E-5 ID:SGTC_176|Compound:1486-1328|FD-Score:3.90|P-value:3.51E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:3.60|P-value:8.86E-4 ID:SGTC_348|Compound:k064-0012|FD-Score:4.11|P-value:1.77E-4 ID:SGTC_437|Compound:s-farnesyl-l-cysteine methyl ester|FD-Score:4.29|P-value:9.92E-5 ID:SGTC_439|Compound:amiodarone|FD-Score:-3.75|P-value:5.34E-4 ID:SGTC_464|Compound:bw-b 70c|FD-Score:4.14|P-value:1.65E-4 ID:SGTC_490|Compound:phenamil|FD-Score:-4.71|P-value:1.96E-5 ID:SGTC_598|Compound:3937-0236|FD-Score:3.84|P-value:4.23E-4 ID:SGTC_776|Compound:4476-4378|FD-Score:3.92|P-value:3.30E-4 ID:SGTC_832|Compound:4083-0019|FD-Score:3.58|P-value:9.36E-4 ID:SGTC_922|Compound:1866-0035|FD-Score:-4.15|P-value:1.47E-4 ID:SGTC_927|Compound:2425-1185|FD-Score:4.82|P-value:1.41E-5 ID:SGTC_939|Compound:1165-0479|FD-Score:4.65|P-value:2.65E-5 ID:SGTC_976|Compound:1348-1067|FD-Score:4.71|P-value:2.12E-5 ID:SGTC_1044|Compound:1222-0021|FD-Score:-4.08|P-value:1.82E-4 ID:SGTC_1070|Compound:indatraline|FD-Score:3.66|P-value:7.44E-4 ID:SGTC_1074|Compound:carmofur|FD-Score:3.66|P-value:7.35E-4 ID:SGTC_1080|Compound:nisoldipine|FD-Score:-4.40|P-value:6.12E-5 ID:SGTC_1085|Compound:doxorubicin|FD-Score:-4.42|P-value:5.68E-5 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:4.97|P-value:7.95E-6 ID:SGTC_1136|Compound:pergolide|FD-Score:3.76|P-value:5.57E-4 ID:SGTC_1240|Compound:0356-0016|FD-Score:-6.11|P-value:4.97E-8 ID:SGTC_1246|Compound:0422-0085|FD-Score:6.22|P-value:3.27E-8 ID:SGTC_1381|Compound:2324-0066|FD-Score:4.37|P-value:7.48E-5 ID:SGTC_1532|Compound:4',5'-dihydroxyflavone|FD-Score:3.88|P-value:3.82E-4 ID:SGTC_1542|Compound:7-hydroxy-3'-methoxyflavone|FD-Score:4.12|P-value:1.76E-4 ID:SGTC_1643|Compound:st009866|FD-Score:-3.85|P-value:3.83E-4 ID:SGTC_1776|Compound:st049249|FD-Score:3.57|P-value:9.80E-4 ID:SGTC_1786|Compound:berberine|FD-Score:3.60|P-value:8.79E-4 ID:SGTC_1827|Compound:berberine|FD-Score:6.07|P-value:6.54E-8 ID:SGTC_1829|Compound:berberine|FD-Score:9.66|P-value:2.21E-17 ID:SGTC_2002|Compound:4023503|FD-Score:3.93|P-value:3.18E-4 ID:SGTC_2015|Compound:5119600|FD-Score:4.58|P-value:3.54E-5 ID:SGTC_2036|Compound:5160441|FD-Score:-4.57|P-value:3.26E-5 ID:SGTC_2041|Compound:5107442|FD-Score:-4.26|P-value:1.00E-4 ID:SGTC_2047|Compound:4141938|FD-Score:3.60|P-value:9.02E-4 ID:SGTC_2050|Compound:5263056|FD-Score:4.94|P-value:8.94E-6 ID:SGTC_2100|Compound:5377183|FD-Score:5.85|P-value:1.82E-7 ID:SGTC_2104|Compound:5389443|FD-Score:4.05|P-value:2.17E-4 ID:SGTC_2111|Compound:5486399|FD-Score:-3.90|P-value:3.29E-4 ID:SGTC_2121|Compound:5257820|FD-Score:6.21|P-value:3.45E-8 ID:SGTC_2178|Compound:5812956|FD-Score:3.99|P-value:2.66E-4 ID:SGTC_2297|Compound:7971671|FD-Score:-4.08|P-value:1.81E-4 ID:SGTC_2300|Compound:7976697|FD-Score:-4.62|P-value:2.79E-5 ID:SGTC_2302|Compound:7771753|FD-Score:5.34|P-value:1.73E-6 ID:SGTC_2344|Compound:7990960|FD-Score:-3.98|P-value:2.54E-4 ID:SGTC_2348|Compound:9022543|FD-Score:-4.06|P-value:1.95E-4 ID:SGTC_2350|Compound:9023895|FD-Score:-4.66|P-value:2.33E-5 ID:SGTC_2376|Compound:9072922|FD-Score:-5.45|P-value:9.84E-7 ID:SGTC_2377|Compound:9073351|FD-Score:-3.82|P-value:4.24E-4 ID:SGTC_2382|Compound:9035899|FD-Score:4.25|P-value:1.14E-4 ID:SGTC_2511|Compound:berberine|FD-Score:3.60|P-value:8.91E-4 ID:SGTC_2530|Compound:3-alpha-hydroxy-4,4-bisnor-8,11,13-podocarpatriene|FD-Score:3.85|P-value:4.16E-4 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:4.82|P-value:1.40E-5 ID:SGTC_2640|Compound:pentamidine|FD-Score:-3.90|P-value:3.28E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:4.22|P-value:1.24E-4 ID:SGTC_2664|Compound:lyso-paf C-16|FD-Score:4.99|P-value:7.33E-6 ID:SGTC_2698|Compound:st077697|FD-Score:4.28|P-value:9.94E-5 ID:SGTC_2757|Compound:clomiphene|FD-Score:4.56|P-value:3.73E-5 ID:SGTC_2782|Compound:7736369|FD-Score:5.61|P-value:5.47E-7 ID:SGTC_2785|Compound:7756463|FD-Score:5.26|P-value:2.44E-6 ID:SGTC_2792|Compound:7535235|FD-Score:3.91|P-value:3.43E-4 ID:SGTC_2834|Compound:9001755|FD-Score:3.67|P-value:7.27E-4 ID:SGTC_2880|Compound:9042983|FD-Score:3.68|P-value:7.00E-4 ID:SGTC_2887|Compound:9044784|FD-Score:3.82|P-value:4.60E-4 ID:SGTC_2893|Compound:9048488|FD-Score:4.24|P-value:1.16E-4 ID:SGTC_2928|Compound:9011484|FD-Score:-3.64|P-value:7.36E-4 ID:SGTC_2948|Compound:9070189|FD-Score:-3.94|P-value:2.88E-4 ID:SGTC_2993|Compound:9054257|FD-Score:3.79|P-value:4.99E-4 ID:SGTC_3065|Compound:9113888|FD-Score:-3.61|P-value:8.02E-4 ID:SGTC_3071|Compound:9117417|FD-Score:4.18|P-value:1.44E-4 ID:SGTC_3081|Compound:9117243|FD-Score:3.83|P-value:4.38E-4 ID:SGTC_3108|Compound:9121785|FD-Score:-4.76|P-value:1.62E-5 ID:SGTC_3116|Compound:9124943|FD-Score:4.32|P-value:8.82E-5 ID:SGTC_3126|Compound:9127922|FD-Score:7.43|P-value:5.16E-11 ID:SGTC_3132|Compound:9126706|FD-Score:-8.06|P-value:1.05E-12 ID:SGTC_3144|Compound:9087057|FD-Score:4.53|P-value:4.15E-5 ID:SGTC_3145|Compound:9085516|FD-Score:7.73|P-value:8.96E-12 ID:SGTC_3194|Compound:9111903|FD-Score:4.79|P-value:1.59E-5 ID:SGTC_3197|Compound:9113331|FD-Score:-5.41|P-value:1.16E-6 ID:SGTC_3308|Compound:9128332|FD-Score:-6.85|P-value:1.13E-9

Top fitness defect scores for YPL093W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_97 0535-0701 11.40 19.1 µM 2.08E-23 60S ribosome export 2 2.60E-30 1.00
2 SGTC_1829 berberine 9.66 14.4 µM 2.21E-17 60S ribosome export 4 2.23E-22 1.76
3 SGTC_3145 9085516 7.73 49.5 µM 8.96E-12 fatty acid desaturase (OLE1) 1 5.31E-15 0.82
4 SGTC_3126 9127922 7.43 49.5 µM 5.16E-11 fatty acid desaturase (OLE1) 8 5.30E-14 1.04
5 SGTC_134 0269-0018 6.35 6.9 µM 1.74E-8 8 1.11E-10 0.55
6 SGTC_1246 0422-0085 6.22 105.0 µM 3.27E-8 2 2.53E-10 1.03
7 SGTC_2121 5257820 6.21 149.6 µM 3.45E-8 1 2.71E-10 1.16
8 SGTC_1827 berberine 6.07 7.2 µM 6.54E-8 60S ribosome export 5 6.27E-10 1.14
9 SGTC_2100 5377183 5.85 190.0 µM 1.82E-7 60S ribosome export 3 2.40E-9 0.28
10 SGTC_2782 7736369 5.61 71.4 µM 5.47E-7 2 1.01E-8 0.47
11 SGTC_2302 7771753 5.34 200.0 µM 1.73E-6 5 4.58E-8 1.30
12 SGTC_2785 7756463 5.26 72.7 µM 2.44E-6 5 7.19E-8 0.07
13 SGTC_66 0109-0187 5.14 42.4 µM 3.99E-6 4 1.37E-7 0.26
14 SGTC_2664 lyso-paf C-16 4.99 73.5 µM 7.33E-6 1 3.04E-7 0.85
15 SGTC_1135 dihydrocapsaicin 4.97 536.7 nM 7.95E-6 2 3.37E-7 0.49
16 SGTC_2050 5263056 4.94 171.0 µM 8.94E-6 fatty acid desaturase (OLE1) 15 3.93E-7 0.26
17 SGTC_2565 isoliquiritigenin 4.82 100.0 µM 1.40E-5 3 7.05E-7 0.06
18 SGTC_927 2425-1185 4.82 123.0 µM 1.41E-5 2 7.11E-7 1.01
19 SGTC_136 0097-0015 4.80 404.5 µM 1.53E-5 60S ribosome export 6 7.96E-7 0.26
20 SGTC_3194 9111903 4.79 49.5 µM 1.59E-5 1 8.38E-7 0.50

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.213 1.19E-35 YHR170W NMD3 het Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex
0.184 6.26E-27 YLR009W RLP24 het Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp
0.180 8.63E-26 YGL055W OLE1 het Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
0.169 7.88E-23 YBR190W_d YBR190W_d het Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W
0.160 9.85E-21 YGL099W LSG1 het Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm
0.159 2.92E-20 YPL131W RPL5 het Ribosomal 60S subunit protein L5; homologous to mammalian ribosomal protein L5 and bacterial L18; binds 5S rRNA and is required for 60S subunit assembly
0.151 1.63E-18 YBR267W REI1 hom Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network
0.146 2.28E-17 YPL235W RVB2 het ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly
0.125 3.14E-13 YPR016C TIF6 het Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits
0.117 1.27E-11 YER112W LSM4 het Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; forms cytoplasmic foci upon DNA replication stress
0.115 2.04E-11 YNL110C NOP15 het Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm
0.115 2.40E-11 YOR206W NOC2 het Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors
0.105 1.06E-9 YMR127C SAS2 hom Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family
0.104 1.48E-9 YOL127W RPL25 het Ribosomal 60S subunit protein L25; primary rRNA-binding ribosomal protein component of large ribosomal subunit; binds to 25S rRNA via a conserved C-terminal motif; homologous to mammalian ribosomal protein L23A and bacterial L23
0.104 1.82E-9 YJR007W SUI2 het Alpha subunit of the translation initiation factor eIF2; eIF2 is involved in identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP; protein abundance increases in response to DNA replication stress