YBL006C / LDB7

Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions

Zygosity: Homozygous strain
fixedexpanded
Profile for YBL006C / LDB7

Click on Significant Values for Screen Details ID:SGTC_36|Compound:0335-0881|FD-Score:6.92|P-value:1.24E-7 ID:SGTC_37|Compound:0566-0070|FD-Score:-5.42|P-value:1.87E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:18.30|P-value:5.74E-43 ID:SGTC_86|Compound:0417-1630|FD-Score:5.12|P-value:7.19E-5 ID:SGTC_103|Compound:0844-0104|FD-Score:-4.46|P-value:3.36E-4 ID:SGTC_119|Compound:0121-0043|FD-Score:4.23|P-value:8.71E-4 ID:SGTC_121|Compound:0557-0495|FD-Score:11.80|P-value:3.93E-19 ID:SGTC_122|Compound:0236-0016|FD-Score:4.91|P-value:1.33E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:8.50|P-value:1.13E-10 ID:SGTC_138|Compound:0850-0259|FD-Score:21.90|P-value:9.72E-61 ID:SGTC_142|Compound:0335-0849|FD-Score:4.73|P-value:2.27E-4 ID:SGTC_146|Compound:3448-8650|FD-Score:5.15|P-value:6.51E-5 ID:SGTC_158|Compound:k038-0087|FD-Score:8.63|P-value:5.83E-11 ID:SGTC_161|Compound:4065-0411|FD-Score:8.03|P-value:1.04E-9 ID:SGTC_165|Compound:k038-0023|FD-Score:4.20|P-value:9.44E-4 ID:SGTC_168|Compound:3970-0862|FD-Score:-5.12|P-value:4.80E-5 ID:SGTC_187|Compound:1488-2104|FD-Score:4.72|P-value:2.29E-4 ID:SGTC_211|Compound:3455-0679|FD-Score:-4.44|P-value:3.51E-4 ID:SGTC_266|Compound:formosanin C|FD-Score:4.97|P-value:1.12E-4 ID:SGTC_294|Compound:k038-0071|FD-Score:5.35|P-value:3.53E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:5.17|P-value:6.18E-5 ID:SGTC_309|Compound:k408-0051|FD-Score:4.64|P-value:2.87E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:6.74|P-value:2.53E-7 ID:SGTC_354|Compound:2783-3500|FD-Score:5.93|P-value:5.17E-6 ID:SGTC_360|Compound:0957-0399|FD-Score:4.59|P-value:3.34E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:-4.32|P-value:4.95E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:5.26|P-value:4.65E-5 ID:SGTC_467|Compound:ro 31-8220|FD-Score:5.40|P-value:3.00E-5 ID:SGTC_514|Compound:4466-0038|FD-Score:9.31|P-value:1.74E-12 ID:SGTC_528|Compound:3492-0019|FD-Score:4.52|P-value:4.03E-4 ID:SGTC_582|Compound:0987-0078|FD-Score:5.61|P-value:1.50E-5 ID:SGTC_666|Compound:0272-0154|FD-Score:13.10|P-value:6.64E-23 ID:SGTC_669|Compound:0108-0021|FD-Score:4.71|P-value:2.35E-4 ID:SGTC_682|Compound:0kpi-0099|FD-Score:6.67|P-value:3.35E-7 ID:SGTC_785|Compound:1270-0111|FD-Score:-4.64|P-value:2.01E-4 ID:SGTC_792|Compound:4534-1957|FD-Score:8.38|P-value:1.97E-10 ID:SGTC_794|Compound:k038-0031|FD-Score:6.20|P-value:1.96E-6 ID:SGTC_837|Compound:0091-0265|FD-Score:4.94|P-value:1.24E-4 ID:SGTC_849|Compound:0386-0493|FD-Score:7.67|P-value:5.32E-9 ID:SGTC_863|Compound:0466-0191|FD-Score:31.60|P-value:1.10E-124 ID:SGTC_916|Compound:4466-0038|FD-Score:4.97|P-value:1.13E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:5.66|P-value:1.29E-5 ID:SGTC_928|Compound:2764-0428|FD-Score:5.16|P-value:6.37E-5 ID:SGTC_951|Compound:1171-0579|FD-Score:7.60|P-value:7.10E-9 ID:SGTC_1013|Compound:4112-3890|FD-Score:6.11|P-value:2.73E-6 ID:SGTC_1048|Compound:3161-0300|FD-Score:-4.40|P-value:3.92E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:6.08|P-value:3.05E-6 ID:SGTC_1067|Compound:clotrimazole|FD-Score:5.02|P-value:9.71E-5 ID:SGTC_1133|Compound:3473-0247|FD-Score:4.93|P-value:1.25E-4 ID:SGTC_1263|Compound:0774-1208|FD-Score:4.25|P-value:8.26E-4 ID:SGTC_1446|Compound:4239-0190|FD-Score:5.14|P-value:6.72E-5 ID:SGTC_1450|Compound:4112-4260|FD-Score:-5.98|P-value:2.76E-6 ID:SGTC_1451|Compound:4152-0210|FD-Score:5.61|P-value:1.49E-5 ID:SGTC_1465|Compound:k213-0056|FD-Score:-5.62|P-value:9.53E-6 ID:SGTC_1473|Compound:k844-0725|FD-Score:5.30|P-value:4.06E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:4.45|P-value:4.82E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:11.30|P-value:1.08E-17 ID:SGTC_1712|Compound:st032288|FD-Score:6.34|P-value:1.20E-6 ID:SGTC_1745|Compound:st081495|FD-Score:8.05|P-value:9.47E-10 ID:SGTC_1754|Compound:st042065|FD-Score:6.86|P-value:1.60E-7 ID:SGTC_1875|Compound:nocodazole|FD-Score:4.33|P-value:6.69E-4 ID:SGTC_1963|Compound:st076565|FD-Score:4.39|P-value:5.63E-4 ID:SGTC_2081|Compound:5214970|FD-Score:5.07|P-value:8.26E-5 ID:SGTC_2157|Compound:5649910|FD-Score:4.58|P-value:3.39E-4 ID:SGTC_2191|Compound:5911152|FD-Score:6.14|P-value:2.40E-6 ID:SGTC_2192|Compound:5915882|FD-Score:8.25|P-value:3.74E-10 ID:SGTC_2196|Compound:6573537|FD-Score:-4.46|P-value:3.38E-4 ID:SGTC_2204|Compound:7233102|FD-Score:-6.83|P-value:1.10E-7 ID:SGTC_2210|Compound:7115885|FD-Score:5.23|P-value:5.14E-5 ID:SGTC_2215|Compound:7188065|FD-Score:6.21|P-value:1.89E-6 ID:SGTC_2218|Compound:6965428|FD-Score:-4.56|P-value:2.51E-4 ID:SGTC_2229|Compound:7354935|FD-Score:9.74|P-value:1.72E-13 ID:SGTC_2231|Compound:micatex|FD-Score:8.44|P-value:1.49E-10 ID:SGTC_2266|Compound:7929956|FD-Score:-4.56|P-value:2.55E-4 ID:SGTC_2278|Compound:7948257|FD-Score:4.59|P-value:3.30E-4 ID:SGTC_2291|Compound:7917025|FD-Score:-4.33|P-value:4.81E-4 ID:SGTC_2297|Compound:7971671|FD-Score:4.35|P-value:6.39E-4 ID:SGTC_2342|Compound:7990637|FD-Score:4.74|P-value:2.17E-4 ID:SGTC_2367|Compound:9070478|FD-Score:5.74|P-value:9.80E-6 ID:SGTC_2412|Compound:st077135|FD-Score:7.37|P-value:1.92E-8 ID:SGTC_2413|Compound:inermin|FD-Score:5.00|P-value:1.04E-4 ID:SGTC_2417|Compound:cerulenin|FD-Score:4.85|P-value:1.59E-4 ID:SGTC_2436|Compound:5633522|FD-Score:6.75|P-value:2.47E-7 ID:SGTC_2502|Compound:avocadyne acetate|FD-Score:6.76|P-value:2.36E-7 ID:SGTC_2506|Compound:ethyl hematommate|FD-Score:-4.11|P-value:8.43E-4 ID:SGTC_2533|Compound:agelasine|FD-Score:6.07|P-value:3.16E-6 ID:SGTC_2557|Compound:derrustone|FD-Score:7.04|P-value:7.78E-8 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:7.31|P-value:2.49E-8 ID:SGTC_2564|Compound:betulinic acid|FD-Score:4.79|P-value:1.88E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.50|P-value:3.25E-24 ID:SGTC_2584|Compound:androsterone|FD-Score:14.10|P-value:2.04E-26 ID:SGTC_2592|Compound:piperlongumine|FD-Score:-4.42|P-value:3.78E-4 ID:SGTC_2619|Compound:obliquin|FD-Score:12.20|P-value:4.83E-20 ID:SGTC_2651|Compound:1327-0036|FD-Score:5.58|P-value:1.66E-5 ID:SGTC_2688|Compound:kanamycin b|FD-Score:8.34|P-value:2.36E-10 ID:SGTC_2729|Compound:fluphenazine|FD-Score:-5.09|P-value:5.29E-5 ID:SGTC_2756|Compound:carbadox|FD-Score:4.24|P-value:8.49E-4 ID:SGTC_2809|Compound:7964133|FD-Score:5.90|P-value:5.78E-6 ID:SGTC_2862|Compound:9027634|FD-Score:6.93|P-value:1.19E-7 ID:SGTC_2912|Compound:7964298|FD-Score:10.20|P-value:1.37E-14 ID:SGTC_2929|Compound:9013348|FD-Score:4.31|P-value:6.96E-4 ID:SGTC_2939|Compound:9044578|FD-Score:5.37|P-value:3.34E-5 ID:SGTC_3015|Compound:9080845|FD-Score:4.65|P-value:2.78E-4 ID:SGTC_3120|Compound:9124077|FD-Score:5.30|P-value:4.04E-5 ID:SGTC_3130|Compound:9127414|FD-Score:4.84|P-value:1.62E-4 ID:SGTC_3143|Compound:9086658|FD-Score:7.67|P-value:5.21E-9 ID:SGTC_3219|Compound:9131112|FD-Score:4.49|P-value:4.31E-4 ID:SGTC_3266|Compound:9136860|FD-Score:23.00|P-value:4.74E-67 ID:SGTC_3281|Compound:9140613|FD-Score:7.24|P-value:3.37E-8 ID:SGTC_3285|Compound:9112818|FD-Score:20.20|P-value:5.94E-52 ID:SGTC_3304|Compound:9125678|FD-Score:6.48|P-value:7.09E-7 ID:SGTC_3311|Compound:9131146|FD-Score:21.10|P-value:1.48E-56 ID:SGTC_3321|Compound:9137793|FD-Score:15.90|P-value:3.65E-33 ID:SGTC_3322|Compound:9139058|FD-Score:11.60|P-value:2.42E-18 ID:SGTC_3331|Compound:9141060|FD-Score:9.90|P-value:6.75E-14 ID:SGTC_3342|Compound:9147791|FD-Score:4.21|P-value:9.20E-4 ID:SGTC_3350|Compound:9150499|FD-Score:11.30|P-value:1.44E-17 ID:SGTC_3351|Compound:9150312|FD-Score:9.87|P-value:8.25E-14 ID:SGTC_3356|Compound:9151811|FD-Score:11.20|P-value:2.19E-17 ID:SGTC_36|Compound:0335-0881|FD-Score:6.92|P-value:1.24E-7 ID:SGTC_37|Compound:0566-0070|FD-Score:-5.42|P-value:1.87E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:18.30|P-value:5.74E-43 ID:SGTC_86|Compound:0417-1630|FD-Score:5.12|P-value:7.19E-5 ID:SGTC_103|Compound:0844-0104|FD-Score:-4.46|P-value:3.36E-4 ID:SGTC_119|Compound:0121-0043|FD-Score:4.23|P-value:8.71E-4 ID:SGTC_121|Compound:0557-0495|FD-Score:11.80|P-value:3.93E-19 ID:SGTC_122|Compound:0236-0016|FD-Score:4.91|P-value:1.33E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:8.50|P-value:1.13E-10 ID:SGTC_138|Compound:0850-0259|FD-Score:21.90|P-value:9.72E-61 ID:SGTC_142|Compound:0335-0849|FD-Score:4.73|P-value:2.27E-4 ID:SGTC_146|Compound:3448-8650|FD-Score:5.15|P-value:6.51E-5 ID:SGTC_158|Compound:k038-0087|FD-Score:8.63|P-value:5.83E-11 ID:SGTC_161|Compound:4065-0411|FD-Score:8.03|P-value:1.04E-9 ID:SGTC_165|Compound:k038-0023|FD-Score:4.20|P-value:9.44E-4 ID:SGTC_168|Compound:3970-0862|FD-Score:-5.12|P-value:4.80E-5 ID:SGTC_187|Compound:1488-2104|FD-Score:4.72|P-value:2.29E-4 ID:SGTC_211|Compound:3455-0679|FD-Score:-4.44|P-value:3.51E-4 ID:SGTC_266|Compound:formosanin C|FD-Score:4.97|P-value:1.12E-4 ID:SGTC_294|Compound:k038-0071|FD-Score:5.35|P-value:3.53E-5 ID:SGTC_304|Compound:1310-0298|FD-Score:5.17|P-value:6.18E-5 ID:SGTC_309|Compound:k408-0051|FD-Score:4.64|P-value:2.87E-4 ID:SGTC_351|Compound:caspofungin|FD-Score:6.74|P-value:2.53E-7 ID:SGTC_354|Compound:2783-3500|FD-Score:5.93|P-value:5.17E-6 ID:SGTC_360|Compound:0957-0399|FD-Score:4.59|P-value:3.34E-4 ID:SGTC_431|Compound:k089-0097|FD-Score:-4.32|P-value:4.95E-4 ID:SGTC_439|Compound:amiodarone|FD-Score:5.26|P-value:4.65E-5 ID:SGTC_467|Compound:ro 31-8220|FD-Score:5.40|P-value:3.00E-5 ID:SGTC_514|Compound:4466-0038|FD-Score:9.31|P-value:1.74E-12 ID:SGTC_528|Compound:3492-0019|FD-Score:4.52|P-value:4.03E-4 ID:SGTC_582|Compound:0987-0078|FD-Score:5.61|P-value:1.50E-5 ID:SGTC_666|Compound:0272-0154|FD-Score:13.10|P-value:6.64E-23 ID:SGTC_669|Compound:0108-0021|FD-Score:4.71|P-value:2.35E-4 ID:SGTC_682|Compound:0kpi-0099|FD-Score:6.67|P-value:3.35E-7 ID:SGTC_785|Compound:1270-0111|FD-Score:-4.64|P-value:2.01E-4 ID:SGTC_792|Compound:4534-1957|FD-Score:8.38|P-value:1.97E-10 ID:SGTC_794|Compound:k038-0031|FD-Score:6.20|P-value:1.96E-6 ID:SGTC_837|Compound:0091-0265|FD-Score:4.94|P-value:1.24E-4 ID:SGTC_849|Compound:0386-0493|FD-Score:7.67|P-value:5.32E-9 ID:SGTC_863|Compound:0466-0191|FD-Score:31.60|P-value:1.10E-124 ID:SGTC_916|Compound:4466-0038|FD-Score:4.97|P-value:1.13E-4 ID:SGTC_923|Compound:1900-2434|FD-Score:5.66|P-value:1.29E-5 ID:SGTC_928|Compound:2764-0428|FD-Score:5.16|P-value:6.37E-5 ID:SGTC_951|Compound:1171-0579|FD-Score:7.60|P-value:7.10E-9 ID:SGTC_1013|Compound:4112-3890|FD-Score:6.11|P-value:2.73E-6 ID:SGTC_1048|Compound:3161-0300|FD-Score:-4.40|P-value:3.92E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:6.08|P-value:3.05E-6 ID:SGTC_1067|Compound:clotrimazole|FD-Score:5.02|P-value:9.71E-5 ID:SGTC_1133|Compound:3473-0247|FD-Score:4.93|P-value:1.25E-4 ID:SGTC_1263|Compound:0774-1208|FD-Score:4.25|P-value:8.26E-4 ID:SGTC_1446|Compound:4239-0190|FD-Score:5.14|P-value:6.72E-5 ID:SGTC_1450|Compound:4112-4260|FD-Score:-5.98|P-value:2.76E-6 ID:SGTC_1451|Compound:4152-0210|FD-Score:5.61|P-value:1.49E-5 ID:SGTC_1465|Compound:k213-0056|FD-Score:-5.62|P-value:9.53E-6 ID:SGTC_1473|Compound:k844-0725|FD-Score:5.30|P-value:4.06E-5 ID:SGTC_1495|Compound:4469-0029|FD-Score:4.45|P-value:4.82E-4 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:11.30|P-value:1.08E-17 ID:SGTC_1712|Compound:st032288|FD-Score:6.34|P-value:1.20E-6 ID:SGTC_1745|Compound:st081495|FD-Score:8.05|P-value:9.47E-10 ID:SGTC_1754|Compound:st042065|FD-Score:6.86|P-value:1.60E-7 ID:SGTC_1875|Compound:nocodazole|FD-Score:4.33|P-value:6.69E-4 ID:SGTC_1963|Compound:st076565|FD-Score:4.39|P-value:5.63E-4 ID:SGTC_2081|Compound:5214970|FD-Score:5.07|P-value:8.26E-5 ID:SGTC_2157|Compound:5649910|FD-Score:4.58|P-value:3.39E-4 ID:SGTC_2191|Compound:5911152|FD-Score:6.14|P-value:2.40E-6 ID:SGTC_2192|Compound:5915882|FD-Score:8.25|P-value:3.74E-10 ID:SGTC_2196|Compound:6573537|FD-Score:-4.46|P-value:3.38E-4 ID:SGTC_2204|Compound:7233102|FD-Score:-6.83|P-value:1.10E-7 ID:SGTC_2210|Compound:7115885|FD-Score:5.23|P-value:5.14E-5 ID:SGTC_2215|Compound:7188065|FD-Score:6.21|P-value:1.89E-6 ID:SGTC_2218|Compound:6965428|FD-Score:-4.56|P-value:2.51E-4 ID:SGTC_2229|Compound:7354935|FD-Score:9.74|P-value:1.72E-13 ID:SGTC_2231|Compound:micatex|FD-Score:8.44|P-value:1.49E-10 ID:SGTC_2266|Compound:7929956|FD-Score:-4.56|P-value:2.55E-4 ID:SGTC_2278|Compound:7948257|FD-Score:4.59|P-value:3.30E-4 ID:SGTC_2291|Compound:7917025|FD-Score:-4.33|P-value:4.81E-4 ID:SGTC_2297|Compound:7971671|FD-Score:4.35|P-value:6.39E-4 ID:SGTC_2342|Compound:7990637|FD-Score:4.74|P-value:2.17E-4 ID:SGTC_2367|Compound:9070478|FD-Score:5.74|P-value:9.80E-6 ID:SGTC_2412|Compound:st077135|FD-Score:7.37|P-value:1.92E-8 ID:SGTC_2413|Compound:inermin|FD-Score:5.00|P-value:1.04E-4 ID:SGTC_2417|Compound:cerulenin|FD-Score:4.85|P-value:1.59E-4 ID:SGTC_2436|Compound:5633522|FD-Score:6.75|P-value:2.47E-7 ID:SGTC_2502|Compound:avocadyne acetate|FD-Score:6.76|P-value:2.36E-7 ID:SGTC_2506|Compound:ethyl hematommate|FD-Score:-4.11|P-value:8.43E-4 ID:SGTC_2533|Compound:agelasine|FD-Score:6.07|P-value:3.16E-6 ID:SGTC_2557|Compound:derrustone|FD-Score:7.04|P-value:7.78E-8 ID:SGTC_2562|Compound:3',7'-dimethoxyflavone|FD-Score:7.31|P-value:2.49E-8 ID:SGTC_2564|Compound:betulinic acid|FD-Score:4.79|P-value:1.88E-4 ID:SGTC_2582|Compound:agaric acid|FD-Score:13.50|P-value:3.25E-24 ID:SGTC_2584|Compound:androsterone|FD-Score:14.10|P-value:2.04E-26 ID:SGTC_2592|Compound:piperlongumine|FD-Score:-4.42|P-value:3.78E-4 ID:SGTC_2619|Compound:obliquin|FD-Score:12.20|P-value:4.83E-20 ID:SGTC_2651|Compound:1327-0036|FD-Score:5.58|P-value:1.66E-5 ID:SGTC_2688|Compound:kanamycin b|FD-Score:8.34|P-value:2.36E-10 ID:SGTC_2729|Compound:fluphenazine|FD-Score:-5.09|P-value:5.29E-5 ID:SGTC_2756|Compound:carbadox|FD-Score:4.24|P-value:8.49E-4 ID:SGTC_2809|Compound:7964133|FD-Score:5.90|P-value:5.78E-6 ID:SGTC_2862|Compound:9027634|FD-Score:6.93|P-value:1.19E-7 ID:SGTC_2912|Compound:7964298|FD-Score:10.20|P-value:1.37E-14 ID:SGTC_2929|Compound:9013348|FD-Score:4.31|P-value:6.96E-4 ID:SGTC_2939|Compound:9044578|FD-Score:5.37|P-value:3.34E-5 ID:SGTC_3015|Compound:9080845|FD-Score:4.65|P-value:2.78E-4 ID:SGTC_3120|Compound:9124077|FD-Score:5.30|P-value:4.04E-5 ID:SGTC_3130|Compound:9127414|FD-Score:4.84|P-value:1.62E-4 ID:SGTC_3143|Compound:9086658|FD-Score:7.67|P-value:5.21E-9 ID:SGTC_3219|Compound:9131112|FD-Score:4.49|P-value:4.31E-4 ID:SGTC_3266|Compound:9136860|FD-Score:23.00|P-value:4.74E-67 ID:SGTC_3281|Compound:9140613|FD-Score:7.24|P-value:3.37E-8 ID:SGTC_3285|Compound:9112818|FD-Score:20.20|P-value:5.94E-52 ID:SGTC_3304|Compound:9125678|FD-Score:6.48|P-value:7.09E-7 ID:SGTC_3311|Compound:9131146|FD-Score:21.10|P-value:1.48E-56 ID:SGTC_3321|Compound:9137793|FD-Score:15.90|P-value:3.65E-33 ID:SGTC_3322|Compound:9139058|FD-Score:11.60|P-value:2.42E-18 ID:SGTC_3331|Compound:9141060|FD-Score:9.90|P-value:6.75E-14 ID:SGTC_3342|Compound:9147791|FD-Score:4.21|P-value:9.20E-4 ID:SGTC_3350|Compound:9150499|FD-Score:11.30|P-value:1.44E-17 ID:SGTC_3351|Compound:9150312|FD-Score:9.87|P-value:8.25E-14 ID:SGTC_3356|Compound:9151811|FD-Score:11.20|P-value:2.19E-17

Top fitness defect scores for YBL006C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_863 0466-0191 31.60 129.0 µM 1.10E-124 cell wall 1 1.52E-219
2 SGTC_3266 9136860 23.00 49.5 µM 4.74E-67 cell wall 1 1.68E-117
3 SGTC_138 0850-0259 21.90 40.9 µM 9.72E-61 cell wall 5 2.52E-106
4 SGTC_3311 9131146 21.10 2.9 µM 1.48E-56 cell wall 1 6.41E-99
5 SGTC_3285 9112818 20.20 20.9 µM 5.94E-52 cell wall 1 9.05E-91
6 SGTC_58 0957-0393 18.30 9.0 µM 5.74E-43 cell wall 18 7.32E-75
7 SGTC_3321 9137793 15.90 26.8 µM 3.65E-33 cell wall 2 1.65E-57
8 SGTC_2584 androsterone 14.10 48.7 µM 2.04E-26 cell wall 7 1.44E-45
9 SGTC_2582 agaric acid 13.50 100.0 µM 3.25E-24 redox potentiating 24 1.14E-41
10 SGTC_666 0272-0154 13.10 136.0 µM 6.64E-23 cell wall 3 2.36E-39
11 SGTC_2619 obliquin 12.20 87.9 µM 4.83E-20 cell wall 14 2.72E-34
12 SGTC_121 0557-0495 11.80 61.3 µM 3.93E-19 calcium & mitochondrial duress 4 1.11E-32
13 SGTC_3322 9139058 11.60 2.1 µM 2.42E-18 cell wall 1 2.75E-31
14 SGTC_1597 7-benzyloxygramine 11.30 47.5 µM 1.08E-17 calcium & mitochondrial duress 12 3.91E-30
15 SGTC_3350 9150499 11.30 3.6 µM 1.44E-17 cell wall 3 6.48E-30
16 SGTC_3356 9151811 11.20 4.5 µM 2.19E-17 cell wall 1 1.36E-29
17 SGTC_2912 7964298 10.20 10.9 µM 1.37E-14 cell wall 15 1.18E-24
18 SGTC_3331 9141060 9.90 2.0 µM 6.75E-14 cell wall 1 1.98E-23
19 SGTC_3351 9150312 9.87 21.6 µM 8.25E-14 cell wall 1 2.82E-23
20 SGTC_2229 7354935 9.74 190.0 µM 1.72E-13 RSC complex & mRNA processing 1 1.04E-22

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Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.535 3.10E-248 YDL066W IDP1 hom Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
0.501 6.47E-213 YJL099W CHS6 hom Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
0.468 2.90E-182 YBR023C CHS3 hom Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan
0.468 6.27E-182 YGR056W RSC1 hom Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook
0.432 2.53E-152 YDL203C ACK1 hom Protein that functions upstream of Pkc1p in the cell wall integrity pathway; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; non-tagged Ack1p is detected in purified mitochondria
0.429 5.77E-150 YKL076C_d PSY1_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 69% of ORF overlaps the uncharacterized ORF YKL075C
0.418 1.03E-141 YPR165W RHO1 het GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)
0.417 1.67E-141 YLR331C_d JIP3_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2
0.417 5.51E-141 YJR142W_p YJR142W_p hom Putative protein of unknown function; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition; nudix hydrolase family member
0.412 2.25E-137 YPL115C BEM3 hom Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
0.394 1.53E-124 YMR124W_p YMR124W_p hom Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene; predicted to have a role in organelle organization
0.391 3.18E-123 YCL005W LDB16 hom Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria
0.359 1.88E-102 YDL021W GPM2 hom Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event
0.354 8.50E-100 YNL314W DAL82 hom Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
0.354 2.03E-99 YJR111C_p YJR111C_p hom Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria