YDR007W / TRP1

Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)

Zygosity: Homozygous strain
fixedexpanded
Profile for YDR007W / TRP1

Click on Significant Values for Screen Details ID:SGTC_10|Compound:0279-0212|FD-Score:14.60|P-value:1.56E-15 ID:SGTC_14|Compound:0354-0009|FD-Score:7.80|P-value:1.43E-5 ID:SGTC_19|Compound:0279-0214|FD-Score:13.70|P-value:8.09E-14 ID:SGTC_24|Compound:0417-1663|FD-Score:8.64|P-value:1.69E-6 ID:SGTC_30|Compound:5-(2-thienylidene)-Rhodanine|FD-Score:12.20|P-value:2.27E-11 ID:SGTC_33|Compound:0986-0033|FD-Score:6.19|P-value:4.69E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:11.20|P-value:6.70E-10 ID:SGTC_50|Compound:0929-0078|FD-Score:13.20|P-value:4.56E-13 ID:SGTC_51|Compound:1013-0126|FD-Score:12.40|P-value:1.30E-11 ID:SGTC_58|Compound:0957-0393|FD-Score:-7.39|P-value:2.18E-5 ID:SGTC_79|Compound:0052-0007|FD-Score:11.20|P-value:9.14E-10 ID:SGTC_109|Compound:0132-0036|FD-Score:9.30|P-value:2.77E-7 ID:SGTC_129|Compound:0088-0017|FD-Score:27.90|P-value:5.53E-52 ID:SGTC_133|Compound:0724-0033|FD-Score:12.50|P-value:8.70E-12 ID:SGTC_134|Compound:0269-0018|FD-Score:13.70|P-value:7.75E-14 ID:SGTC_161|Compound:4065-0411|FD-Score:7.70|P-value:1.79E-5 ID:SGTC_167|Compound:3672-0051|FD-Score:5.93|P-value:7.60E-4 ID:SGTC_176|Compound:1486-1328|FD-Score:8.23|P-value:4.85E-6 ID:SGTC_178|Compound:4092-0806|FD-Score:5.96|P-value:7.30E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:19.60|P-value:1.46E-26 ID:SGTC_194|Compound:1486-1323|FD-Score:7.83|P-value:1.30E-5 ID:SGTC_201|Compound:4262-0159|FD-Score:8.92|P-value:8.13E-7 ID:SGTC_204|Compound:1543-0184|FD-Score:9.39|P-value:2.18E-7 ID:SGTC_205|Compound:1486-1330|FD-Score:8.14|P-value:6.13E-6 ID:SGTC_207|Compound:4185-0010|FD-Score:17.80|P-value:2.39E-22 ID:SGTC_208|Compound:k072-0098|FD-Score:6.76|P-value:1.47E-4 ID:SGTC_285|Compound:1486-1325|FD-Score:5.92|P-value:7.78E-4 ID:SGTC_337|Compound:1315-0038|FD-Score:6.40|P-value:3.09E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:6.83|P-value:1.27E-4 ID:SGTC_505|Compound:gw-5074|FD-Score:8.24|P-value:4.74E-6 ID:SGTC_515|Compound:4092-1064|FD-Score:9.08|P-value:5.27E-7 ID:SGTC_523|Compound:1934-0222|FD-Score:7.61|P-value:2.23E-5 ID:SGTC_526|Compound:4469-0568|FD-Score:7.56|P-value:2.52E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:11.40|P-value:3.54E-10 ID:SGTC_556|Compound:4058-0063|FD-Score:6.06|P-value:5.99E-4 ID:SGTC_581|Compound:0958-0271|FD-Score:8.50|P-value:2.46E-6 ID:SGTC_596|Compound:1155-0152|FD-Score:7.34|P-value:4.14E-5 ID:SGTC_621|Compound:3584-0052|FD-Score:7.83|P-value:1.33E-5 ID:SGTC_636|Compound:0kpi-0074|FD-Score:6.21|P-value:4.46E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:12.50|P-value:8.80E-12 ID:SGTC_638|Compound:3970-0837|FD-Score:6.09|P-value:5.67E-4 ID:SGTC_673|Compound:1082-0474|FD-Score:5.84|P-value:9.09E-4 ID:SGTC_677|Compound:0929-0063|FD-Score:6.27|P-value:3.96E-4 ID:SGTC_723|Compound:4182-0001|FD-Score:12.90|P-value:1.75E-12 ID:SGTC_727|Compound:3032-0951|FD-Score:7.19|P-value:5.82E-5 ID:SGTC_748|Compound:0136-0228|FD-Score:9.87|P-value:5.41E-8 ID:SGTC_767|Compound:0929-0023|FD-Score:8.06|P-value:7.44E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:7.37|P-value:3.85E-5 ID:SGTC_819|Compound:1013-0258|FD-Score:13.40|P-value:2.36E-13 ID:SGTC_820|Compound:1582-0060|FD-Score:7.17|P-value:6.00E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:7.86|P-value:1.23E-5 ID:SGTC_834|Compound:0312-0008|FD-Score:6.83|P-value:1.26E-4 ID:SGTC_844|Compound:0330-0132|FD-Score:5.97|P-value:7.14E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:6.69|P-value:1.70E-4 ID:SGTC_874|Compound:0599-0792|FD-Score:7.90|P-value:1.12E-5 ID:SGTC_912|Compound:3474-0017|FD-Score:7.49|P-value:2.95E-5 ID:SGTC_981|Compound:1488-1094|FD-Score:8.60|P-value:1.91E-6 ID:SGTC_1002|Compound:4049-0206|FD-Score:7.71|P-value:1.77E-5 ID:SGTC_1003|Compound:4049-0218|FD-Score:6.52|P-value:2.40E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:10.80|P-value:2.56E-9 ID:SGTC_1005|Compound:4092-0690|FD-Score:12.40|P-value:1.19E-11 ID:SGTC_1041|Compound:0206-0046|FD-Score:11.60|P-value:1.85E-10 ID:SGTC_1047|Compound:2043-3044|FD-Score:6.42|P-value:2.96E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:7.48|P-value:3.00E-5 ID:SGTC_1072|Compound:oxiconazole|FD-Score:6.66|P-value:1.80E-4 ID:SGTC_1095|Compound:3-[3,5-dibromo-4-hydroxybenzoyl]-2-ethylbenzofuran|FD-Score:5.86|P-value:8.70E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:5.91|P-value:8.01E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.89|P-value:8.23E-4 ID:SGTC_1159|Compound:4092-0538|FD-Score:7.65|P-value:2.04E-5 ID:SGTC_1160|Compound:4092-0570|FD-Score:9.48|P-value:1.66E-7 ID:SGTC_1161|Compound:k007-0610|FD-Score:6.56|P-value:2.23E-4 ID:SGTC_1166|Compound:k206-0078|FD-Score:8.21|P-value:5.11E-6 ID:SGTC_1181|Compound:1222-0449|FD-Score:6.25|P-value:4.15E-4 ID:SGTC_1219|Compound:1469-0211|FD-Score:7.90|P-value:1.10E-5 ID:SGTC_1263|Compound:0774-1208|FD-Score:7.00|P-value:8.75E-5 ID:SGTC_1282|Compound:0886-0010|FD-Score:6.68|P-value:1.75E-4 ID:SGTC_1284|Compound:0929-0043|FD-Score:6.72|P-value:1.59E-4 ID:SGTC_1304|Compound:1165-0502|FD-Score:11.90|P-value:5.91E-11 ID:SGTC_1313|Compound:1220-0047|FD-Score:6.73|P-value:1.58E-4 ID:SGTC_1335|Compound:1486-0900|FD-Score:7.82|P-value:1.36E-5 ID:SGTC_1350|Compound:1495-0454|FD-Score:9.10|P-value:4.89E-7 ID:SGTC_1361|Compound:1608-0041|FD-Score:5.91|P-value:7.93E-4 ID:SGTC_1372|Compound:2752-0194|FD-Score:7.92|P-value:1.06E-5 ID:SGTC_1382|Compound:3002-2117|FD-Score:6.24|P-value:4.20E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:9.24|P-value:3.28E-7 ID:SGTC_1421|Compound:4029-0249|FD-Score:5.89|P-value:8.29E-4 ID:SGTC_1423|Compound:4048-0112|FD-Score:14.40|P-value:4.25E-15 ID:SGTC_1427|Compound:4048-4900|FD-Score:13.60|P-value:8.65E-14 ID:SGTC_1435|Compound:4092-0789|FD-Score:6.94|P-value:1.00E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:7.42|P-value:3.43E-5 ID:SGTC_1475|Compound:4092-1048|FD-Score:7.11|P-value:6.95E-5 ID:SGTC_1482|Compound:3346-2049|FD-Score:16.30|P-value:6.43E-19 ID:SGTC_1496|Compound:4469-0713|FD-Score:7.91|P-value:1.09E-5 ID:SGTC_1510|Compound:1123-0200|FD-Score:11.00|P-value:1.69E-9 ID:SGTC_1511|Compound:0906-3109|FD-Score:9.20|P-value:3.76E-7 ID:SGTC_1520|Compound:flindersine|FD-Score:9.50|P-value:1.58E-7 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:6.36|P-value:3.33E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:12.70|P-value:3.09E-12 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:9.19|P-value:3.79E-7 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:11.10|P-value:9.39E-10 ID:SGTC_1603|Compound:st002045|FD-Score:10.00|P-value:3.38E-8 ID:SGTC_1617|Compound:st002906|FD-Score:9.37|P-value:2.29E-7 ID:SGTC_1636|Compound:st007707|FD-Score:18.20|P-value:3.42E-23 ID:SGTC_1649|Compound:st011737|FD-Score:9.26|P-value:3.16E-7 ID:SGTC_1655|Compound:st012546|FD-Score:6.71|P-value:1.64E-4 ID:SGTC_1672|Compound:st016598|FD-Score:6.23|P-value:4.34E-4 ID:SGTC_1673|Compound:st016611|FD-Score:14.80|P-value:6.73E-16 ID:SGTC_1697|Compound:st025554|FD-Score:11.20|P-value:7.20E-10 ID:SGTC_1699|Compound:st031318|FD-Score:10.20|P-value:1.76E-8 ID:SGTC_1706|Compound:st031321|FD-Score:6.32|P-value:3.59E-4 ID:SGTC_1715|Compound:st032160|FD-Score:19.20|P-value:1.06E-25 ID:SGTC_1717|Compound:st033143|FD-Score:7.11|P-value:6.89E-5 ID:SGTC_1720|Compound:st037298|FD-Score:6.98|P-value:9.13E-5 ID:SGTC_1750|Compound:st081859|FD-Score:10.50|P-value:7.01E-9 ID:SGTC_1752|Compound:st044819|FD-Score:7.45|P-value:3.19E-5 ID:SGTC_1757|Compound:st041620|FD-Score:10.90|P-value:2.38E-9 ID:SGTC_1764|Compound:st044502|FD-Score:6.92|P-value:1.06E-4 ID:SGTC_1797|Compound:st048695|FD-Score:14.50|P-value:2.40E-15 ID:SGTC_1824|Compound:st053723|FD-Score:13.60|P-value:9.03E-14 ID:SGTC_1847|Compound:st056231|FD-Score:5.95|P-value:7.40E-4 ID:SGTC_1865|Compound:st057639|FD-Score:6.56|P-value:2.23E-4 ID:SGTC_1868|Compound:st057644|FD-Score:6.90|P-value:1.09E-4 ID:SGTC_1881|Compound:5652484|FD-Score:19.20|P-value:1.21E-25 ID:SGTC_1882|Compound:5615643|FD-Score:22.40|P-value:3.90E-34 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:25.40|P-value:1.84E-43 ID:SGTC_1909|Compound:st060837|FD-Score:11.90|P-value:7.29E-11 ID:SGTC_1933|Compound:st074711|FD-Score:6.21|P-value:4.47E-4 ID:SGTC_1937|Compound:st074714|FD-Score:6.99|P-value:8.92E-5 ID:SGTC_1999|Compound:st074831|FD-Score:18.30|P-value:2.39E-23 ID:SGTC_2003|Compound:4023581|FD-Score:8.31|P-value:3.98E-6 ID:SGTC_2010|Compound:4012422|FD-Score:6.99|P-value:9.10E-5 ID:SGTC_2024|Compound:5144227|FD-Score:6.83|P-value:1.27E-4 ID:SGTC_2032|Compound:5185112|FD-Score:6.27|P-value:4.01E-4 ID:SGTC_2034|Compound:5197015|FD-Score:6.76|P-value:1.47E-4 ID:SGTC_2036|Compound:5160441|FD-Score:13.60|P-value:9.36E-14 ID:SGTC_2038|Compound:4100038|FD-Score:22.90|P-value:8.85E-36 ID:SGTC_2056|Compound:5235370|FD-Score:14.90|P-value:3.98E-16 ID:SGTC_2093|Compound:5331342|FD-Score:16.20|P-value:9.99E-19 ID:SGTC_2137|Compound:5261020|FD-Score:19.80|P-value:3.96E-27 ID:SGTC_2148|Compound:5546263|FD-Score:5.79|P-value:9.93E-4 ID:SGTC_2163|Compound:5671233|FD-Score:8.59|P-value:1.96E-6 ID:SGTC_2164|Compound:5685496|FD-Score:6.52|P-value:2.42E-4 ID:SGTC_2165|Compound:5727197|FD-Score:7.69|P-value:1.84E-5 ID:SGTC_2175|Compound:5807670|FD-Score:6.92|P-value:1.04E-4 ID:SGTC_2197|Compound:6588183|FD-Score:6.95|P-value:9.72E-5 ID:SGTC_2198|Compound:6589944|FD-Score:6.92|P-value:1.05E-4 ID:SGTC_2231|Compound:micatex|FD-Score:6.15|P-value:5.00E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:19.20|P-value:1.31E-25 ID:SGTC_2238|Compound:6671620|FD-Score:11.90|P-value:6.48E-11 ID:SGTC_2249|Compound:haloperidol|FD-Score:9.18|P-value:3.98E-7 ID:SGTC_2254|Compound:7938975|FD-Score:18.90|P-value:7.82E-25 ID:SGTC_2271|Compound:7849410|FD-Score:8.67|P-value:1.56E-6 ID:SGTC_2286|Compound:7945697|FD-Score:10.90|P-value:2.14E-9 ID:SGTC_2301|Compound:7769476|FD-Score:11.20|P-value:7.07E-10 ID:SGTC_2322|Compound:7413319|FD-Score:11.10|P-value:1.23E-9 ID:SGTC_2353|Compound:9059630|FD-Score:6.04|P-value:6.19E-4 ID:SGTC_2376|Compound:9072922|FD-Score:9.78|P-value:7.10E-8 ID:SGTC_2377|Compound:9073351|FD-Score:7.71|P-value:1.74E-5 ID:SGTC_2384|Compound:9036245|FD-Score:24.00|P-value:4.41E-39 ID:SGTC_2385|Compound:9074692|FD-Score:6.37|P-value:3.27E-4 ID:SGTC_2387|Compound:9077560|FD-Score:8.17|P-value:5.73E-6 ID:SGTC_2396|Compound:5342950|FD-Score:8.11|P-value:6.69E-6 ID:SGTC_2409|Compound:alverine citrate|FD-Score:7.16|P-value:6.21E-5 ID:SGTC_2428|Compound:5615643|FD-Score:6.81|P-value:1.32E-4 ID:SGTC_2437|Compound:5741531|FD-Score:8.08|P-value:7.18E-6 ID:SGTC_2445|Compound:5742597|FD-Score:8.83|P-value:1.04E-6 ID:SGTC_2447|Compound:5741742|FD-Score:6.06|P-value:5.97E-4 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:14.10|P-value:1.16E-14 ID:SGTC_2472|Compound:5377652|FD-Score:13.60|P-value:9.98E-14 ID:SGTC_2478|Compound:5763493|FD-Score:12.60|P-value:5.13E-12 ID:SGTC_2481|Compound:5478948|FD-Score:-5.83|P-value:6.05E-4 ID:SGTC_2486|Compound:5283202|FD-Score:12.80|P-value:2.04E-12 ID:SGTC_2488|Compound:5268135|FD-Score:25.10|P-value:1.44E-42 ID:SGTC_2500|Compound:5-alpha-androstan-3,17-dione|FD-Score:6.10|P-value:5.56E-4 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:6.40|P-value:3.09E-4 ID:SGTC_2523|Compound:spermine|FD-Score:8.46|P-value:2.75E-6 ID:SGTC_2524|Compound:avocatin b|FD-Score:12.10|P-value:2.78E-11 ID:SGTC_2527|Compound:2',3'-dihydroxy-4-methoxy-4'-ethoxybenzophenone|FD-Score:7.78|P-value:1.48E-5 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:19.90|P-value:2.34E-27 ID:SGTC_2607|Compound:solasodine|FD-Score:27.30|P-value:6.27E-50 ID:SGTC_2616|Compound:abietic acid|FD-Score:6.13|P-value:5.23E-4 ID:SGTC_2618|Compound:avocadyne|FD-Score:21.40|P-value:2.64E-31 ID:SGTC_2620|Compound:irigenin|FD-Score:8.74|P-value:1.31E-6 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:11.00|P-value:1.36E-9 ID:SGTC_2650|Compound:prasterone|FD-Score:8.79|P-value:1.15E-6 ID:SGTC_2699|Compound:st077704|FD-Score:8.37|P-value:3.45E-6 ID:SGTC_2725|Compound:haloperidol|FD-Score:10.70|P-value:3.96E-9 ID:SGTC_2741|Compound:miltefosine|FD-Score:8.84|P-value:1.00E-6 ID:SGTC_2752|Compound:diclazuril|FD-Score:12.70|P-value:4.14E-12 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:21.80|P-value:2.29E-32 ID:SGTC_2778|Compound:tioconazole|FD-Score:9.03|P-value:6.01E-7 ID:SGTC_2833|Compound:9001315|FD-Score:6.00|P-value:6.75E-4 ID:SGTC_2883|Compound:9059145|FD-Score:-5.76|P-value:6.94E-4 ID:SGTC_2887|Compound:9044784|FD-Score:8.76|P-value:1.25E-6 ID:SGTC_2890|Compound:9046729|FD-Score:-5.66|P-value:8.24E-4 ID:SGTC_2939|Compound:9044578|FD-Score:18.20|P-value:2.65E-23 ID:SGTC_2948|Compound:9070189|FD-Score:11.60|P-value:1.96E-10 ID:SGTC_3018|Compound:9082602|FD-Score:8.34|P-value:3.68E-6 ID:SGTC_3066|Compound:9117245|FD-Score:9.99|P-value:3.74E-8 ID:SGTC_3284|Compound:9108171|FD-Score:8.90|P-value:8.45E-7 ID:SGTC_3308|Compound:9128332|FD-Score:23.60|P-value:1.19E-37 ID:SGTC_3317|Compound:9138495|FD-Score:6.15|P-value:5.09E-4 ID:SGTC_3334|Compound:9142812|FD-Score:7.70|P-value:1.81E-5 ID:SGTC_3342|Compound:9147791|FD-Score:7.32|P-value:4.35E-5 ID:SGTC_10|Compound:0279-0212|FD-Score:14.60|P-value:1.56E-15 ID:SGTC_14|Compound:0354-0009|FD-Score:7.80|P-value:1.43E-5 ID:SGTC_19|Compound:0279-0214|FD-Score:13.70|P-value:8.09E-14 ID:SGTC_24|Compound:0417-1663|FD-Score:8.64|P-value:1.69E-6 ID:SGTC_30|Compound:5-(2-thienylidene)-Rhodanine|FD-Score:12.20|P-value:2.27E-11 ID:SGTC_33|Compound:0986-0033|FD-Score:6.19|P-value:4.69E-4 ID:SGTC_41|Compound:0478-0632|FD-Score:11.20|P-value:6.70E-10 ID:SGTC_50|Compound:0929-0078|FD-Score:13.20|P-value:4.56E-13 ID:SGTC_51|Compound:1013-0126|FD-Score:12.40|P-value:1.30E-11 ID:SGTC_58|Compound:0957-0393|FD-Score:-7.39|P-value:2.18E-5 ID:SGTC_79|Compound:0052-0007|FD-Score:11.20|P-value:9.14E-10 ID:SGTC_109|Compound:0132-0036|FD-Score:9.30|P-value:2.77E-7 ID:SGTC_129|Compound:0088-0017|FD-Score:27.90|P-value:5.53E-52 ID:SGTC_133|Compound:0724-0033|FD-Score:12.50|P-value:8.70E-12 ID:SGTC_134|Compound:0269-0018|FD-Score:13.70|P-value:7.75E-14 ID:SGTC_161|Compound:4065-0411|FD-Score:7.70|P-value:1.79E-5 ID:SGTC_167|Compound:3672-0051|FD-Score:5.93|P-value:7.60E-4 ID:SGTC_176|Compound:1486-1328|FD-Score:8.23|P-value:4.85E-6 ID:SGTC_178|Compound:4092-0806|FD-Score:5.96|P-value:7.30E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:19.60|P-value:1.46E-26 ID:SGTC_194|Compound:1486-1323|FD-Score:7.83|P-value:1.30E-5 ID:SGTC_201|Compound:4262-0159|FD-Score:8.92|P-value:8.13E-7 ID:SGTC_204|Compound:1543-0184|FD-Score:9.39|P-value:2.18E-7 ID:SGTC_205|Compound:1486-1330|FD-Score:8.14|P-value:6.13E-6 ID:SGTC_207|Compound:4185-0010|FD-Score:17.80|P-value:2.39E-22 ID:SGTC_208|Compound:k072-0098|FD-Score:6.76|P-value:1.47E-4 ID:SGTC_285|Compound:1486-1325|FD-Score:5.92|P-value:7.78E-4 ID:SGTC_337|Compound:1315-0038|FD-Score:6.40|P-value:3.09E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:6.83|P-value:1.27E-4 ID:SGTC_505|Compound:gw-5074|FD-Score:8.24|P-value:4.74E-6 ID:SGTC_515|Compound:4092-1064|FD-Score:9.08|P-value:5.27E-7 ID:SGTC_523|Compound:1934-0222|FD-Score:7.61|P-value:2.23E-5 ID:SGTC_526|Compound:4469-0568|FD-Score:7.56|P-value:2.52E-5 ID:SGTC_542|Compound:3381-0244|FD-Score:11.40|P-value:3.54E-10 ID:SGTC_556|Compound:4058-0063|FD-Score:6.06|P-value:5.99E-4 ID:SGTC_581|Compound:0958-0271|FD-Score:8.50|P-value:2.46E-6 ID:SGTC_596|Compound:1155-0152|FD-Score:7.34|P-value:4.14E-5 ID:SGTC_621|Compound:3584-0052|FD-Score:7.83|P-value:1.33E-5 ID:SGTC_636|Compound:0kpi-0074|FD-Score:6.21|P-value:4.46E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:12.50|P-value:8.80E-12 ID:SGTC_638|Compound:3970-0837|FD-Score:6.09|P-value:5.67E-4 ID:SGTC_673|Compound:1082-0474|FD-Score:5.84|P-value:9.09E-4 ID:SGTC_677|Compound:0929-0063|FD-Score:6.27|P-value:3.96E-4 ID:SGTC_723|Compound:4182-0001|FD-Score:12.90|P-value:1.75E-12 ID:SGTC_727|Compound:3032-0951|FD-Score:7.19|P-value:5.82E-5 ID:SGTC_748|Compound:0136-0228|FD-Score:9.87|P-value:5.41E-8 ID:SGTC_767|Compound:0929-0023|FD-Score:8.06|P-value:7.44E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:7.37|P-value:3.85E-5 ID:SGTC_819|Compound:1013-0258|FD-Score:13.40|P-value:2.36E-13 ID:SGTC_820|Compound:1582-0060|FD-Score:7.17|P-value:6.00E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:7.86|P-value:1.23E-5 ID:SGTC_834|Compound:0312-0008|FD-Score:6.83|P-value:1.26E-4 ID:SGTC_844|Compound:0330-0132|FD-Score:5.97|P-value:7.14E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:6.69|P-value:1.70E-4 ID:SGTC_874|Compound:0599-0792|FD-Score:7.90|P-value:1.12E-5 ID:SGTC_912|Compound:3474-0017|FD-Score:7.49|P-value:2.95E-5 ID:SGTC_981|Compound:1488-1094|FD-Score:8.60|P-value:1.91E-6 ID:SGTC_1002|Compound:4049-0206|FD-Score:7.71|P-value:1.77E-5 ID:SGTC_1003|Compound:4049-0218|FD-Score:6.52|P-value:2.40E-4 ID:SGTC_1004|Compound:4084-0029|FD-Score:10.80|P-value:2.56E-9 ID:SGTC_1005|Compound:4092-0690|FD-Score:12.40|P-value:1.19E-11 ID:SGTC_1041|Compound:0206-0046|FD-Score:11.60|P-value:1.85E-10 ID:SGTC_1047|Compound:2043-3044|FD-Score:6.42|P-value:2.96E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:7.48|P-value:3.00E-5 ID:SGTC_1072|Compound:oxiconazole|FD-Score:6.66|P-value:1.80E-4 ID:SGTC_1095|Compound:3-[3,5-dibromo-4-hydroxybenzoyl]-2-ethylbenzofuran|FD-Score:5.86|P-value:8.70E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:5.91|P-value:8.01E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.89|P-value:8.23E-4 ID:SGTC_1159|Compound:4092-0538|FD-Score:7.65|P-value:2.04E-5 ID:SGTC_1160|Compound:4092-0570|FD-Score:9.48|P-value:1.66E-7 ID:SGTC_1161|Compound:k007-0610|FD-Score:6.56|P-value:2.23E-4 ID:SGTC_1166|Compound:k206-0078|FD-Score:8.21|P-value:5.11E-6 ID:SGTC_1181|Compound:1222-0449|FD-Score:6.25|P-value:4.15E-4 ID:SGTC_1219|Compound:1469-0211|FD-Score:7.90|P-value:1.10E-5 ID:SGTC_1263|Compound:0774-1208|FD-Score:7.00|P-value:8.75E-5 ID:SGTC_1282|Compound:0886-0010|FD-Score:6.68|P-value:1.75E-4 ID:SGTC_1284|Compound:0929-0043|FD-Score:6.72|P-value:1.59E-4 ID:SGTC_1304|Compound:1165-0502|FD-Score:11.90|P-value:5.91E-11 ID:SGTC_1313|Compound:1220-0047|FD-Score:6.73|P-value:1.58E-4 ID:SGTC_1335|Compound:1486-0900|FD-Score:7.82|P-value:1.36E-5 ID:SGTC_1350|Compound:1495-0454|FD-Score:9.10|P-value:4.89E-7 ID:SGTC_1361|Compound:1608-0041|FD-Score:5.91|P-value:7.93E-4 ID:SGTC_1372|Compound:2752-0194|FD-Score:7.92|P-value:1.06E-5 ID:SGTC_1382|Compound:3002-2117|FD-Score:6.24|P-value:4.20E-4 ID:SGTC_1418|Compound:3966-3099|FD-Score:9.24|P-value:3.28E-7 ID:SGTC_1421|Compound:4029-0249|FD-Score:5.89|P-value:8.29E-4 ID:SGTC_1423|Compound:4048-0112|FD-Score:14.40|P-value:4.25E-15 ID:SGTC_1427|Compound:4048-4900|FD-Score:13.60|P-value:8.65E-14 ID:SGTC_1435|Compound:4092-0789|FD-Score:6.94|P-value:1.00E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:7.42|P-value:3.43E-5 ID:SGTC_1475|Compound:4092-1048|FD-Score:7.11|P-value:6.95E-5 ID:SGTC_1482|Compound:3346-2049|FD-Score:16.30|P-value:6.43E-19 ID:SGTC_1496|Compound:4469-0713|FD-Score:7.91|P-value:1.09E-5 ID:SGTC_1510|Compound:1123-0200|FD-Score:11.00|P-value:1.69E-9 ID:SGTC_1511|Compound:0906-3109|FD-Score:9.20|P-value:3.76E-7 ID:SGTC_1520|Compound:flindersine|FD-Score:9.50|P-value:1.58E-7 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:6.36|P-value:3.33E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:12.70|P-value:3.09E-12 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:9.19|P-value:3.79E-7 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:11.10|P-value:9.39E-10 ID:SGTC_1603|Compound:st002045|FD-Score:10.00|P-value:3.38E-8 ID:SGTC_1617|Compound:st002906|FD-Score:9.37|P-value:2.29E-7 ID:SGTC_1636|Compound:st007707|FD-Score:18.20|P-value:3.42E-23 ID:SGTC_1649|Compound:st011737|FD-Score:9.26|P-value:3.16E-7 ID:SGTC_1655|Compound:st012546|FD-Score:6.71|P-value:1.64E-4 ID:SGTC_1672|Compound:st016598|FD-Score:6.23|P-value:4.34E-4 ID:SGTC_1673|Compound:st016611|FD-Score:14.80|P-value:6.73E-16 ID:SGTC_1697|Compound:st025554|FD-Score:11.20|P-value:7.20E-10 ID:SGTC_1699|Compound:st031318|FD-Score:10.20|P-value:1.76E-8 ID:SGTC_1706|Compound:st031321|FD-Score:6.32|P-value:3.59E-4 ID:SGTC_1715|Compound:st032160|FD-Score:19.20|P-value:1.06E-25 ID:SGTC_1717|Compound:st033143|FD-Score:7.11|P-value:6.89E-5 ID:SGTC_1720|Compound:st037298|FD-Score:6.98|P-value:9.13E-5 ID:SGTC_1750|Compound:st081859|FD-Score:10.50|P-value:7.01E-9 ID:SGTC_1752|Compound:st044819|FD-Score:7.45|P-value:3.19E-5 ID:SGTC_1757|Compound:st041620|FD-Score:10.90|P-value:2.38E-9 ID:SGTC_1764|Compound:st044502|FD-Score:6.92|P-value:1.06E-4 ID:SGTC_1797|Compound:st048695|FD-Score:14.50|P-value:2.40E-15 ID:SGTC_1824|Compound:st053723|FD-Score:13.60|P-value:9.03E-14 ID:SGTC_1847|Compound:st056231|FD-Score:5.95|P-value:7.40E-4 ID:SGTC_1865|Compound:st057639|FD-Score:6.56|P-value:2.23E-4 ID:SGTC_1868|Compound:st057644|FD-Score:6.90|P-value:1.09E-4 ID:SGTC_1881|Compound:5652484|FD-Score:19.20|P-value:1.21E-25 ID:SGTC_1882|Compound:5615643|FD-Score:22.40|P-value:3.90E-34 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:25.40|P-value:1.84E-43 ID:SGTC_1909|Compound:st060837|FD-Score:11.90|P-value:7.29E-11 ID:SGTC_1933|Compound:st074711|FD-Score:6.21|P-value:4.47E-4 ID:SGTC_1937|Compound:st074714|FD-Score:6.99|P-value:8.92E-5 ID:SGTC_1999|Compound:st074831|FD-Score:18.30|P-value:2.39E-23 ID:SGTC_2003|Compound:4023581|FD-Score:8.31|P-value:3.98E-6 ID:SGTC_2010|Compound:4012422|FD-Score:6.99|P-value:9.10E-5 ID:SGTC_2024|Compound:5144227|FD-Score:6.83|P-value:1.27E-4 ID:SGTC_2032|Compound:5185112|FD-Score:6.27|P-value:4.01E-4 ID:SGTC_2034|Compound:5197015|FD-Score:6.76|P-value:1.47E-4 ID:SGTC_2036|Compound:5160441|FD-Score:13.60|P-value:9.36E-14 ID:SGTC_2038|Compound:4100038|FD-Score:22.90|P-value:8.85E-36 ID:SGTC_2056|Compound:5235370|FD-Score:14.90|P-value:3.98E-16 ID:SGTC_2093|Compound:5331342|FD-Score:16.20|P-value:9.99E-19 ID:SGTC_2137|Compound:5261020|FD-Score:19.80|P-value:3.96E-27 ID:SGTC_2148|Compound:5546263|FD-Score:5.79|P-value:9.93E-4 ID:SGTC_2163|Compound:5671233|FD-Score:8.59|P-value:1.96E-6 ID:SGTC_2164|Compound:5685496|FD-Score:6.52|P-value:2.42E-4 ID:SGTC_2165|Compound:5727197|FD-Score:7.69|P-value:1.84E-5 ID:SGTC_2175|Compound:5807670|FD-Score:6.92|P-value:1.04E-4 ID:SGTC_2197|Compound:6588183|FD-Score:6.95|P-value:9.72E-5 ID:SGTC_2198|Compound:6589944|FD-Score:6.92|P-value:1.05E-4 ID:SGTC_2231|Compound:micatex|FD-Score:6.15|P-value:5.00E-4 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:19.20|P-value:1.31E-25 ID:SGTC_2238|Compound:6671620|FD-Score:11.90|P-value:6.48E-11 ID:SGTC_2249|Compound:haloperidol|FD-Score:9.18|P-value:3.98E-7 ID:SGTC_2254|Compound:7938975|FD-Score:18.90|P-value:7.82E-25 ID:SGTC_2271|Compound:7849410|FD-Score:8.67|P-value:1.56E-6 ID:SGTC_2286|Compound:7945697|FD-Score:10.90|P-value:2.14E-9 ID:SGTC_2301|Compound:7769476|FD-Score:11.20|P-value:7.07E-10 ID:SGTC_2322|Compound:7413319|FD-Score:11.10|P-value:1.23E-9 ID:SGTC_2353|Compound:9059630|FD-Score:6.04|P-value:6.19E-4 ID:SGTC_2376|Compound:9072922|FD-Score:9.78|P-value:7.10E-8 ID:SGTC_2377|Compound:9073351|FD-Score:7.71|P-value:1.74E-5 ID:SGTC_2384|Compound:9036245|FD-Score:24.00|P-value:4.41E-39 ID:SGTC_2385|Compound:9074692|FD-Score:6.37|P-value:3.27E-4 ID:SGTC_2387|Compound:9077560|FD-Score:8.17|P-value:5.73E-6 ID:SGTC_2396|Compound:5342950|FD-Score:8.11|P-value:6.69E-6 ID:SGTC_2409|Compound:alverine citrate|FD-Score:7.16|P-value:6.21E-5 ID:SGTC_2428|Compound:5615643|FD-Score:6.81|P-value:1.32E-4 ID:SGTC_2437|Compound:5741531|FD-Score:8.08|P-value:7.18E-6 ID:SGTC_2445|Compound:5742597|FD-Score:8.83|P-value:1.04E-6 ID:SGTC_2447|Compound:5741742|FD-Score:6.06|P-value:5.97E-4 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:14.10|P-value:1.16E-14 ID:SGTC_2472|Compound:5377652|FD-Score:13.60|P-value:9.98E-14 ID:SGTC_2478|Compound:5763493|FD-Score:12.60|P-value:5.13E-12 ID:SGTC_2481|Compound:5478948|FD-Score:-5.83|P-value:6.05E-4 ID:SGTC_2486|Compound:5283202|FD-Score:12.80|P-value:2.04E-12 ID:SGTC_2488|Compound:5268135|FD-Score:25.10|P-value:1.44E-42 ID:SGTC_2500|Compound:5-alpha-androstan-3,17-dione|FD-Score:6.10|P-value:5.56E-4 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:6.40|P-value:3.09E-4 ID:SGTC_2523|Compound:spermine|FD-Score:8.46|P-value:2.75E-6 ID:SGTC_2524|Compound:avocatin b|FD-Score:12.10|P-value:2.78E-11 ID:SGTC_2527|Compound:2',3'-dihydroxy-4-methoxy-4'-ethoxybenzophenone|FD-Score:7.78|P-value:1.48E-5 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:19.90|P-value:2.34E-27 ID:SGTC_2607|Compound:solasodine|FD-Score:27.30|P-value:6.27E-50 ID:SGTC_2616|Compound:abietic acid|FD-Score:6.13|P-value:5.23E-4 ID:SGTC_2618|Compound:avocadyne|FD-Score:21.40|P-value:2.64E-31 ID:SGTC_2620|Compound:irigenin|FD-Score:8.74|P-value:1.31E-6 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:11.00|P-value:1.36E-9 ID:SGTC_2650|Compound:prasterone|FD-Score:8.79|P-value:1.15E-6 ID:SGTC_2699|Compound:st077704|FD-Score:8.37|P-value:3.45E-6 ID:SGTC_2725|Compound:haloperidol|FD-Score:10.70|P-value:3.96E-9 ID:SGTC_2741|Compound:miltefosine|FD-Score:8.84|P-value:1.00E-6 ID:SGTC_2752|Compound:diclazuril|FD-Score:12.70|P-value:4.14E-12 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:21.80|P-value:2.29E-32 ID:SGTC_2778|Compound:tioconazole|FD-Score:9.03|P-value:6.01E-7 ID:SGTC_2833|Compound:9001315|FD-Score:6.00|P-value:6.75E-4 ID:SGTC_2883|Compound:9059145|FD-Score:-5.76|P-value:6.94E-4 ID:SGTC_2887|Compound:9044784|FD-Score:8.76|P-value:1.25E-6 ID:SGTC_2890|Compound:9046729|FD-Score:-5.66|P-value:8.24E-4 ID:SGTC_2939|Compound:9044578|FD-Score:18.20|P-value:2.65E-23 ID:SGTC_2948|Compound:9070189|FD-Score:11.60|P-value:1.96E-10 ID:SGTC_3018|Compound:9082602|FD-Score:8.34|P-value:3.68E-6 ID:SGTC_3066|Compound:9117245|FD-Score:9.99|P-value:3.74E-8 ID:SGTC_3284|Compound:9108171|FD-Score:8.90|P-value:8.45E-7 ID:SGTC_3308|Compound:9128332|FD-Score:23.60|P-value:1.19E-37 ID:SGTC_3317|Compound:9138495|FD-Score:6.15|P-value:5.09E-4 ID:SGTC_3334|Compound:9142812|FD-Score:7.70|P-value:1.81E-5 ID:SGTC_3342|Compound:9147791|FD-Score:7.32|P-value:4.35E-5

Top fitness defect scores for YDR007W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_129 0088-0017 27.90 176.6 µM 5.53E-52 1 2.31E-171
2 SGTC_2607 solasodine 27.30 47.4 µM 6.27E-50 4 1.97E-164
3 SGTC_1883 5-benzylidenerhodanine 25.40 20.0 µM 1.84E-43 TRP & mitochondrial translation 1 1.28E-142
4 SGTC_2488 5268135 25.10 45.7 µM 1.44E-42 2 1.32E-139
5 SGTC_2384 9036245 24.00 200.0 µM 4.41E-39 1 7.58E-128
6 SGTC_3308 9128332 23.60 17.6 µM 1.19E-37 plasma membrane duress 4 5.06E-123
7 SGTC_2038 4100038 22.90 31.0 µM 8.85E-36 plasma membrane duress 4 1.04E-116
8 SGTC_1882 5615643 22.40 20.0 µM 3.90E-34 TRP & mitochondrial translation 1 3.65E-111
9 SGTC_2758 dehydroepiandrosterone 21.80 69.3 µM 2.29E-32 5 3.32E-105
10 SGTC_2618 avocadyne 21.40 43.4 µM 2.64E-31 5 1.27E-101
11 SGTC_2540 epiandrosterone 19.90 100.0 µM 2.34E-27 1 2.55E-88
12 SGTC_2137 5261020 19.80 140.0 µM 3.96E-27 1 1.50E-87
13 SGTC_180 1486-1293 19.60 102.8 µM 1.46E-26 3 1.21E-85
14 SGTC_1715 st032160 19.20 10.2 µM 1.06E-25 1 9.81E-83
15 SGTC_1881 5652484 19.20 16.0 µM 1.21E-25 TRP & mitochondrial translation 1 1.50E-82
16 SGTC_2232 chlorophetanol 19.20 41.5 µM 1.31E-25 TRP & mitochondrial translation 5 1.96E-82
17 SGTC_2254 7938975 18.90 95.2 µM 7.82E-25 4 8.12E-80
18 SGTC_1999 st074831 18.30 12.5 µM 2.39E-23 plasma membrane duress 1 8.20E-75
19 SGTC_2939 9044578 18.20 71.4 µM 2.65E-23 4 1.15E-74
20 SGTC_1636 st007707 18.20 68.9 µM 3.42E-23 2 2.74E-74

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.753 0 YDR008C_d YDR008C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.739 0 YDR354W TRP4 hom Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
0.704 0 YKL211C TRP3 hom Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
0.696 0 YGL026C TRP5 hom Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis
0.679 0 YEL009C GCN4 hom Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
0.655 0 YER090W TRP2 hom Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p
0.629 0 YDR283C GCN2 hom Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control
0.609 0 YKR026C GCN3 hom Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
0.607 0 YDR127W ARO1 hom Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
0.532 8.59E-244 YDR035W ARO3 hom 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan
0.515 6.07E-226 YGL117W_p YGL117W_p hom Putative protein of unknown function
0.489 2.55E-201 YFR009W GCN20 hom Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA
0.394 4.71E-125 YGL148W ARO2 hom Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress
0.200 1.29E-31 YIR023W DAL81 hom Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
0.189 1.87E-28 YDL226C GCS1 hom ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p