HIPHOP chemogenomics database
YFL049W / SWP82 
Member of the SWI/SNF chromatin remodeling complex; has an as yet unidentified role in the complex; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p; relocates to the cytosol under hypoxic conditions
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YFL049W deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Cofit Genes
Download Cofitness data (tab-delimited text) (excel)| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|---|---|---|---|---|
| 0.152 | 9.42E-19 | YJL135W_d | YJL135W_d | hom | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified genes YJL134W/LCB3 |
| 0.134 | 5.52E-15 | YJR092W | BUD4 | hom | Anillin-like protein involved in bud-site selection; required for the axial budding pattern; localizes with septins to the bud neck in mitosis and may constitute an axial landmark for the next round of budding; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; in vivo substrate of Cdc28p/Clb2p |
| 0.132 | 1.51E-14 | YBR090C_p | YBR090C_p | hom | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus |
| 0.117 | 1.31E-11 | YLR390W-A | CCW14 | hom | Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall |
| 0.114 | 3.61E-11 | YGR055W | MUP1 | hom | High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake |
| 0.114 | 4.20E-11 | YNR044W | AGA1 | hom | Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds |
| 0.113 | 4.91E-11 | YDR042C_p | YDR042C_p | hom | Putative protein of unknown function; expression is increased in ssu72-ts69 mutant |
| 0.109 | 2.44E-10 | YOR238W_p | YOR238W_p | hom | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
| 0.108 | 3.52E-10 | YMR036C | MIH1 | hom | Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25 |
| 0.107 | 4.83E-10 | YDR109C_p | YDR109C_p | hom | Putative kinase |
| 0.106 | 6.68E-10 | YFL036W | RPO41 | hom | Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation |
| 0.105 | 1.22E-9 | YFL020C | PAU5 | hom | Member of the seripauperin multigene family encoded mainly in subtelomeric regions; induced during alcoholic fermentation; induced by low temperature and also by anaerobic conditions; negatively regulated by oxygen and repressed by heme |
| 0.102 | 3.05E-9 | YOL075C_p | YOL075C_p | hom | Putative ABC transporter |
| 0.100 | 7.47E-9 | YGL102C_d | YGL102C_d | het | Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential RPL28 gene encoding a large subunit ribosomal protein |
| 0.099 | 7.73E-9 | YLR255C_d | YLR255C_d | hom | Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data |