HIPHOP chemogenomics database
YJR154W_p 
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YJR154W deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Cofit Genes
Download Cofitness data (tab-delimited text) (excel)| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|---|---|---|---|---|
| 0.127 | 1.26E-13 | YGR287C | IMA1 | hom | Major isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase); required for isomaltose utilization; specificity for isomaltose, alpha-methylglucoside, and palatinose; member of the IMA isomaltase family |
| 0.110 | 1.82E-10 | YHL039W | EFM1 | hom | Lysine methyltransferase involved in the monomethylation of eEF1A (Tef1p/Tef2p); SET-domain family member; predicted involvement in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
| 0.110 | 1.94E-10 | YGR279C | SCW4 | hom | Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating |
| 0.109 | 2.19E-10 | YDR210W_p | YDR210W_p | hom | Predicted tail-anchored plasma membrane protein containing a conserved CYSTM module; related proteins in other organisms may be involved in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery |
| 0.107 | 4.33E-10 | YDR164C | SEC1 | het | Sm-like protein involved in docking and fusion of exocytic vesicles; binds to assembled SNARE complexes at the membrane and stimulates membrane fusion; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function |
| 0.107 | 6.01E-10 | YPL262W | FUM1 | hom | Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria |
| 0.102 | 3.56E-9 | YDR249C_p | YDR249C_p | hom | Putative protein of unknown function |
| 0.100 | 5.65E-9 | YGL128C | CWC23 | het | Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to E. coli DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p |
| 0.100 | 6.77E-9 | YBL034C | STU1 | het | Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles |
| 0.099 | 9.87E-9 | YIL019W | FAF1 | het | Protein required for pre-rRNA processing and 40S ribosomal subunit assembly |
| 0.096 | 2.21E-8 | YMR168C | CEP3 | het | Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain |
| 0.093 | 5.87E-8 | YOL158C | ENB1 | hom | Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment |
| 0.091 | 1.10E-7 | YGR161W-C_p | YGR161W-C_p | hom | Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species |
| 0.091 | 1.42E-7 | YEL011W | GLC3 | hom | Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress |
| 0.091 | 1.45E-7 | YGR044C | RME1 | hom | Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-alpha2 regulator; mediates cell type control of sporulation; relocalizes from nucleus to cytoplasm upon DNA replication stress |