YKL211C / TRP3

Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p

Zygosity: Homozygous strain
fixedexpanded
Profile for YKL211C / TRP3

Click on Significant Values for Screen Details ID:SGTC_10|Compound:0279-0212|FD-Score:7.83|P-value:3.85E-4 ID:SGTC_19|Compound:0279-0214|FD-Score:8.59|P-value:1.07E-4 ID:SGTC_50|Compound:0929-0078|FD-Score:10.80|P-value:1.35E-6 ID:SGTC_51|Compound:1013-0126|FD-Score:12.00|P-value:8.57E-8 ID:SGTC_71|Compound:0417-1750|FD-Score:10.30|P-value:3.84E-6 ID:SGTC_74|Compound:000s-0487|FD-Score:7.72|P-value:4.63E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:15.80|P-value:1.95E-12 ID:SGTC_161|Compound:4065-0411|FD-Score:10.30|P-value:3.71E-6 ID:SGTC_176|Compound:1486-1328|FD-Score:16.60|P-value:1.39E-13 ID:SGTC_180|Compound:1486-1293|FD-Score:18.90|P-value:5.18E-17 ID:SGTC_204|Compound:1543-0184|FD-Score:9.60|P-value:1.64E-5 ID:SGTC_207|Compound:4185-0010|FD-Score:11.70|P-value:1.78E-7 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:7.86|P-value:3.69E-4 ID:SGTC_365|Compound:0121-0052|FD-Score:7.34|P-value:8.34E-4 ID:SGTC_386|Compound:1509-0011|FD-Score:8.02|P-value:2.82E-4 ID:SGTC_409|Compound:arachidonic acid|FD-Score:7.80|P-value:4.04E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:10.40|P-value:3.09E-6 ID:SGTC_505|Compound:gw-5074|FD-Score:18.40|P-value:3.39E-16 ID:SGTC_523|Compound:1934-0222|FD-Score:11.00|P-value:9.50E-7 ID:SGTC_525|Compound:k781-2675|FD-Score:-7.21|P-value:3.94E-4 ID:SGTC_526|Compound:4469-0568|FD-Score:9.79|P-value:1.11E-5 ID:SGTC_530|Compound:4358-1714|FD-Score:7.26|P-value:9.41E-4 ID:SGTC_542|Compound:3381-0244|FD-Score:12.50|P-value:2.40E-8 ID:SGTC_556|Compound:4058-0063|FD-Score:8.66|P-value:9.35E-5 ID:SGTC_558|Compound:k064-0027|FD-Score:-7.80|P-value:1.47E-4 ID:SGTC_581|Compound:0958-0271|FD-Score:8.83|P-value:6.90E-5 ID:SGTC_636|Compound:0kpi-0074|FD-Score:7.23|P-value:9.89E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:9.48|P-value:2.06E-5 ID:SGTC_638|Compound:3970-0837|FD-Score:9.77|P-value:1.18E-5 ID:SGTC_676|Compound:falcarinol|FD-Score:9.34|P-value:2.71E-5 ID:SGTC_723|Compound:4182-0001|FD-Score:9.09|P-value:4.33E-5 ID:SGTC_737|Compound:1950-0117|FD-Score:8.10|P-value:2.45E-4 ID:SGTC_748|Compound:0136-0228|FD-Score:9.04|P-value:4.70E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:9.87|P-value:9.61E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:8.24|P-value:1.97E-4 ID:SGTC_813|Compound:k007-0158|FD-Score:8.06|P-value:2.63E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:19.10|P-value:2.07E-17 ID:SGTC_823|Compound:0417-1665|FD-Score:18.30|P-value:4.06E-16 ID:SGTC_826|Compound:1683-5028|FD-Score:10.60|P-value:2.16E-6 ID:SGTC_844|Compound:0330-0132|FD-Score:8.03|P-value:2.80E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:9.87|P-value:9.54E-6 ID:SGTC_903|Compound:1134-0042|FD-Score:11.60|P-value:2.46E-7 ID:SGTC_926|Compound:2268-1401|FD-Score:11.20|P-value:6.06E-7 ID:SGTC_933|Compound:2914-0560|FD-Score:8.53|P-value:1.17E-4 ID:SGTC_981|Compound:1488-1094|FD-Score:8.69|P-value:8.85E-5 ID:SGTC_1011|Compound:4112-3381|FD-Score:10.60|P-value:1.97E-6 ID:SGTC_1041|Compound:0206-0046|FD-Score:11.10|P-value:7.14E-7 ID:SGTC_1047|Compound:2043-3044|FD-Score:12.20|P-value:5.20E-8 ID:SGTC_1056|Compound:3448-1962|FD-Score:8.22|P-value:2.03E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:13.80|P-value:8.76E-10 ID:SGTC_1076|Compound:itraconazole|FD-Score:8.44|P-value:1.38E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:18.10|P-value:8.26E-16 ID:SGTC_1114|Compound:scopoletin|FD-Score:9.01|P-value:5.02E-5 ID:SGTC_1117|Compound:retinoic acid|FD-Score:8.34|P-value:1.65E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:13.90|P-value:6.39E-10 ID:SGTC_1131|Compound:3454-3128|FD-Score:10.10|P-value:6.23E-6 ID:SGTC_1156|Compound:4092-0367|FD-Score:7.86|P-value:3.67E-4 ID:SGTC_1159|Compound:4092-0538|FD-Score:12.60|P-value:1.81E-8 ID:SGTC_1160|Compound:4092-0570|FD-Score:11.70|P-value:1.73E-7 ID:SGTC_1161|Compound:k007-0610|FD-Score:12.40|P-value:2.95E-8 ID:SGTC_1172|Compound:0370-0043|FD-Score:8.84|P-value:6.84E-5 ID:SGTC_1181|Compound:1222-0449|FD-Score:12.60|P-value:1.86E-8 ID:SGTC_1189|Compound:1431-2119|FD-Score:12.80|P-value:1.05E-8 ID:SGTC_1193|Compound:1488-0126|FD-Score:22.80|P-value:4.12E-24 ID:SGTC_1194|Compound:1488-0194|FD-Score:23.40|P-value:2.29E-25 ID:SGTC_1213|Compound:1315-0166|FD-Score:9.27|P-value:3.09E-5 ID:SGTC_1304|Compound:1165-0502|FD-Score:9.21|P-value:3.46E-5 ID:SGTC_1313|Compound:1220-0047|FD-Score:8.04|P-value:2.75E-4 ID:SGTC_1427|Compound:4048-4900|FD-Score:13.20|P-value:3.66E-9 ID:SGTC_1455|Compound:4262-0120|FD-Score:9.22|P-value:3.41E-5 ID:SGTC_1457|Compound:k015-0032|FD-Score:7.60|P-value:5.53E-4 ID:SGTC_1474|Compound:0330-0125|FD-Score:10.20|P-value:5.15E-6 ID:SGTC_1482|Compound:3346-2049|FD-Score:20.80|P-value:2.66E-20 ID:SGTC_1494|Compound:4358-1428|FD-Score:14.70|P-value:5.92E-11 ID:SGTC_1496|Compound:4469-0713|FD-Score:16.40|P-value:3.64E-13 ID:SGTC_1520|Compound:flindersine|FD-Score:11.50|P-value:2.83E-7 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:17.40|P-value:1.23E-14 ID:SGTC_1546|Compound:5-methoxyflavanone|FD-Score:14.60|P-value:9.28E-11 ID:SGTC_1548|Compound:st061468|FD-Score:7.61|P-value:5.49E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:17.20|P-value:2.09E-14 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:8.08|P-value:2.56E-4 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:9.61|P-value:1.60E-5 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:8.88|P-value:6.33E-5 ID:SGTC_1600|Compound:coumarin 106|FD-Score:8.03|P-value:2.76E-4 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:7.42|P-value:7.38E-4 ID:SGTC_1603|Compound:st002045|FD-Score:34.00|P-value:2.07E-51 ID:SGTC_1608|Compound:st001473|FD-Score:13.00|P-value:6.13E-9 ID:SGTC_1617|Compound:st002906|FD-Score:36.10|P-value:6.70E-58 ID:SGTC_1623|Compound:st003709|FD-Score:7.30|P-value:8.80E-4 ID:SGTC_1636|Compound:st007707|FD-Score:13.60|P-value:1.53E-9 ID:SGTC_1649|Compound:st011737|FD-Score:11.50|P-value:2.85E-7 ID:SGTC_1654|Compound:st012436|FD-Score:7.70|P-value:4.77E-4 ID:SGTC_1655|Compound:st012546|FD-Score:7.44|P-value:7.10E-4 ID:SGTC_1671|Compound:st016596|FD-Score:9.97|P-value:7.80E-6 ID:SGTC_1672|Compound:st016598|FD-Score:11.80|P-value:1.38E-7 ID:SGTC_1673|Compound:st016611|FD-Score:20.20|P-value:3.53E-19 ID:SGTC_1697|Compound:st025554|FD-Score:8.37|P-value:1.55E-4 ID:SGTC_1699|Compound:st031318|FD-Score:11.90|P-value:1.03E-7 ID:SGTC_1710|Compound:st031758|FD-Score:8.84|P-value:6.83E-5 ID:SGTC_1715|Compound:st032160|FD-Score:7.69|P-value:4.82E-4 ID:SGTC_1720|Compound:st037298|FD-Score:7.88|P-value:3.53E-4 ID:SGTC_1750|Compound:st081859|FD-Score:7.44|P-value:7.13E-4 ID:SGTC_1778|Compound:st046819|FD-Score:8.14|P-value:2.30E-4 ID:SGTC_1797|Compound:st048695|FD-Score:12.40|P-value:2.97E-8 ID:SGTC_1824|Compound:st053723|FD-Score:18.80|P-value:6.17E-17 ID:SGTC_1833|Compound:st055984|FD-Score:7.69|P-value:4.85E-4 ID:SGTC_1835|Compound:st008666|FD-Score:11.90|P-value:1.04E-7 ID:SGTC_1837|Compound:st055472|FD-Score:7.23|P-value:9.86E-4 ID:SGTC_1838|Compound:st055369|FD-Score:9.56|P-value:1.76E-5 ID:SGTC_1847|Compound:st056231|FD-Score:8.40|P-value:1.47E-4 ID:SGTC_1865|Compound:st057639|FD-Score:8.28|P-value:1.84E-4 ID:SGTC_1868|Compound:st057644|FD-Score:9.57|P-value:1.72E-5 ID:SGTC_1881|Compound:5652484|FD-Score:14.90|P-value:3.60E-11 ID:SGTC_1882|Compound:5615643|FD-Score:14.10|P-value:3.44E-10 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:20.80|P-value:3.08E-20 ID:SGTC_1909|Compound:st060837|FD-Score:23.20|P-value:5.93E-25 ID:SGTC_1921|Compound:5740136|FD-Score:7.52|P-value:6.31E-4 ID:SGTC_1933|Compound:st074711|FD-Score:8.55|P-value:1.15E-4 ID:SGTC_1937|Compound:st074714|FD-Score:9.62|P-value:1.57E-5 ID:SGTC_1952|Compound:st077036|FD-Score:8.42|P-value:1.42E-4 ID:SGTC_1972|Compound:st070201|FD-Score:12.50|P-value:2.23E-8 ID:SGTC_1975|Compound:st070967|FD-Score:22.00|P-value:1.30E-22 ID:SGTC_1999|Compound:st074831|FD-Score:11.40|P-value:3.38E-7 ID:SGTC_2024|Compound:5144227|FD-Score:12.00|P-value:9.38E-8 ID:SGTC_2036|Compound:5160441|FD-Score:11.60|P-value:2.11E-7 ID:SGTC_2038|Compound:4100038|FD-Score:21.80|P-value:3.55E-22 ID:SGTC_2056|Compound:5235370|FD-Score:11.20|P-value:5.09E-7 ID:SGTC_2064|Compound:5220758|FD-Score:7.33|P-value:8.50E-4 ID:SGTC_2093|Compound:5331342|FD-Score:13.60|P-value:1.42E-9 ID:SGTC_2094|Compound:5332512|FD-Score:9.98|P-value:7.61E-6 ID:SGTC_2122|Compound:5258151|FD-Score:9.67|P-value:1.42E-5 ID:SGTC_2137|Compound:5261020|FD-Score:12.10|P-value:7.15E-8 ID:SGTC_2148|Compound:5546263|FD-Score:8.57|P-value:1.09E-4 ID:SGTC_2168|Compound:5727979|FD-Score:9.23|P-value:3.32E-5 ID:SGTC_2175|Compound:5807670|FD-Score:10.20|P-value:4.74E-6 ID:SGTC_2197|Compound:6588183|FD-Score:20.90|P-value:1.89E-20 ID:SGTC_2198|Compound:6589944|FD-Score:11.70|P-value:1.67E-7 ID:SGTC_2203|Compound:7227154|FD-Score:10.60|P-value:2.09E-6 ID:SGTC_2224|Compound:6650123|FD-Score:8.81|P-value:7.13E-5 ID:SGTC_2231|Compound:micatex|FD-Score:12.20|P-value:5.70E-8 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:25.20|P-value:4.42E-29 ID:SGTC_2233|Compound:sulbentine|FD-Score:9.43|P-value:2.28E-5 ID:SGTC_2249|Compound:haloperidol|FD-Score:11.40|P-value:3.65E-7 ID:SGTC_2254|Compound:7938975|FD-Score:35.20|P-value:3.85E-55 ID:SGTC_2255|Compound:7941087|FD-Score:11.00|P-value:9.56E-7 ID:SGTC_2267|Compound:7931562|FD-Score:11.50|P-value:2.58E-7 ID:SGTC_2268|Compound:7933382|FD-Score:7.74|P-value:4.47E-4 ID:SGTC_2273|Compound:7815444|FD-Score:8.10|P-value:2.45E-4 ID:SGTC_2296|Compound:7971656|FD-Score:20.50|P-value:1.07E-19 ID:SGTC_2299|Compound:7976368|FD-Score:10.40|P-value:3.20E-6 ID:SGTC_2301|Compound:7769476|FD-Score:14.40|P-value:1.46E-10 ID:SGTC_2304|Compound:7443016|FD-Score:10.30|P-value:3.74E-6 ID:SGTC_2312|Compound:7706453|FD-Score:12.30|P-value:3.95E-8 ID:SGTC_2376|Compound:9072922|FD-Score:10.20|P-value:4.90E-6 ID:SGTC_2377|Compound:9073351|FD-Score:8.01|P-value:2.85E-4 ID:SGTC_2384|Compound:9036245|FD-Score:12.90|P-value:9.36E-9 ID:SGTC_2408|Compound:sulbentine|FD-Score:11.20|P-value:5.13E-7 ID:SGTC_2409|Compound:alverine citrate|FD-Score:49.20|P-value:4.73E-106 ID:SGTC_2411|Compound:st077133|FD-Score:9.06|P-value:4.57E-5 ID:SGTC_2413|Compound:inermin|FD-Score:9.42|P-value:2.29E-5 ID:SGTC_2416|Compound:tofa|FD-Score:12.80|P-value:1.30E-8 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:9.49|P-value:2.01E-5 ID:SGTC_2472|Compound:5377652|FD-Score:12.30|P-value:4.40E-8 ID:SGTC_2478|Compound:5763493|FD-Score:16.20|P-value:5.62E-13 ID:SGTC_2486|Compound:5283202|FD-Score:16.10|P-value:8.85E-13 ID:SGTC_2488|Compound:5268135|FD-Score:17.60|P-value:5.56E-15 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:9.08|P-value:4.38E-5 ID:SGTC_2508|Compound:celastrol|FD-Score:7.36|P-value:8.05E-4 ID:SGTC_2523|Compound:spermine|FD-Score:8.92|P-value:5.86E-5 ID:SGTC_2524|Compound:avocatin b|FD-Score:9.48|P-value:2.04E-5 ID:SGTC_2527|Compound:2',3'-dihydroxy-4-methoxy-4'-ethoxybenzophenone|FD-Score:8.00|P-value:2.92E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:17.80|P-value:3.09E-15 ID:SGTC_2554|Compound:13-methyl-4,4-bisnor-8,11,13-podocarpatrien-3-one|FD-Score:7.65|P-value:5.13E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:37.30|P-value:9.13E-62 ID:SGTC_2616|Compound:abietic acid|FD-Score:15.10|P-value:2.13E-11 ID:SGTC_2618|Compound:avocadyne|FD-Score:30.20|P-value:3.91E-41 ID:SGTC_2620|Compound:irigenin|FD-Score:11.90|P-value:1.00E-7 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:13.20|P-value:4.20E-9 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:10.10|P-value:5.97E-6 ID:SGTC_2650|Compound:prasterone|FD-Score:8.23|P-value:2.00E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.59|P-value:1.06E-4 ID:SGTC_2669|Compound:eugenol|FD-Score:9.64|P-value:1.52E-5 ID:SGTC_2683|Compound:piperine|FD-Score:10.30|P-value:3.71E-6 ID:SGTC_2684|Compound:capsaicin|FD-Score:10.50|P-value:2.70E-6 ID:SGTC_2699|Compound:st077704|FD-Score:14.80|P-value:4.46E-11 ID:SGTC_2725|Compound:haloperidol|FD-Score:14.50|P-value:1.26E-10 ID:SGTC_2741|Compound:miltefosine|FD-Score:7.48|P-value:6.70E-4 ID:SGTC_2752|Compound:diclazuril|FD-Score:30.20|P-value:5.97E-41 ID:SGTC_2757|Compound:clomiphene|FD-Score:10.40|P-value:3.09E-6 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:27.10|P-value:2.87E-33 ID:SGTC_2776|Compound:terbinafine|FD-Score:19.40|P-value:6.52E-18 ID:SGTC_2777|Compound:climbazole|FD-Score:12.80|P-value:1.17E-8 ID:SGTC_2778|Compound:tioconazole|FD-Score:20.70|P-value:3.54E-20 ID:SGTC_2816|Compound:7982706|FD-Score:9.05|P-value:4.64E-5 ID:SGTC_2852|Compound:9023854|FD-Score:10.60|P-value:1.99E-6 ID:SGTC_2862|Compound:9027634|FD-Score:-7.51|P-value:2.37E-4 ID:SGTC_2880|Compound:9042983|FD-Score:10.40|P-value:2.99E-6 ID:SGTC_2910|Compound:7948405|FD-Score:8.01|P-value:2.88E-4 ID:SGTC_2921|Compound:7974240|FD-Score:7.80|P-value:4.05E-4 ID:SGTC_2939|Compound:9044578|FD-Score:18.20|P-value:5.36E-16 ID:SGTC_2948|Compound:9070189|FD-Score:11.20|P-value:5.78E-7 ID:SGTC_3018|Compound:9082602|FD-Score:28.70|P-value:2.59E-37 ID:SGTC_3060|Compound:1327-0027|FD-Score:8.40|P-value:1.48E-4 ID:SGTC_3283|Compound:9109332|FD-Score:-9.15|P-value:1.18E-5 ID:SGTC_3308|Compound:9128332|FD-Score:30.40|P-value:1.24E-41 ID:SGTC_3317|Compound:9138495|FD-Score:7.74|P-value:4.46E-4 ID:SGTC_3318|Compound:9139014|FD-Score:10.40|P-value:3.26E-6 ID:SGTC_10|Compound:0279-0212|FD-Score:7.83|P-value:3.85E-4 ID:SGTC_19|Compound:0279-0214|FD-Score:8.59|P-value:1.07E-4 ID:SGTC_50|Compound:0929-0078|FD-Score:10.80|P-value:1.35E-6 ID:SGTC_51|Compound:1013-0126|FD-Score:12.00|P-value:8.57E-8 ID:SGTC_71|Compound:0417-1750|FD-Score:10.30|P-value:3.84E-6 ID:SGTC_74|Compound:000s-0487|FD-Score:7.72|P-value:4.63E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:15.80|P-value:1.95E-12 ID:SGTC_161|Compound:4065-0411|FD-Score:10.30|P-value:3.71E-6 ID:SGTC_176|Compound:1486-1328|FD-Score:16.60|P-value:1.39E-13 ID:SGTC_180|Compound:1486-1293|FD-Score:18.90|P-value:5.18E-17 ID:SGTC_204|Compound:1543-0184|FD-Score:9.60|P-value:1.64E-5 ID:SGTC_207|Compound:4185-0010|FD-Score:11.70|P-value:1.78E-7 ID:SGTC_243|Compound:5hr heat shock (37°C) + splitomicin|FD-Score:7.86|P-value:3.69E-4 ID:SGTC_365|Compound:0121-0052|FD-Score:7.34|P-value:8.34E-4 ID:SGTC_386|Compound:1509-0011|FD-Score:8.02|P-value:2.82E-4 ID:SGTC_409|Compound:arachidonic acid|FD-Score:7.80|P-value:4.04E-4 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:10.40|P-value:3.09E-6 ID:SGTC_505|Compound:gw-5074|FD-Score:18.40|P-value:3.39E-16 ID:SGTC_523|Compound:1934-0222|FD-Score:11.00|P-value:9.50E-7 ID:SGTC_525|Compound:k781-2675|FD-Score:-7.21|P-value:3.94E-4 ID:SGTC_526|Compound:4469-0568|FD-Score:9.79|P-value:1.11E-5 ID:SGTC_530|Compound:4358-1714|FD-Score:7.26|P-value:9.41E-4 ID:SGTC_542|Compound:3381-0244|FD-Score:12.50|P-value:2.40E-8 ID:SGTC_556|Compound:4058-0063|FD-Score:8.66|P-value:9.35E-5 ID:SGTC_558|Compound:k064-0027|FD-Score:-7.80|P-value:1.47E-4 ID:SGTC_581|Compound:0958-0271|FD-Score:8.83|P-value:6.90E-5 ID:SGTC_636|Compound:0kpi-0074|FD-Score:7.23|P-value:9.89E-4 ID:SGTC_637|Compound:1181-0519|FD-Score:9.48|P-value:2.06E-5 ID:SGTC_638|Compound:3970-0837|FD-Score:9.77|P-value:1.18E-5 ID:SGTC_676|Compound:falcarinol|FD-Score:9.34|P-value:2.71E-5 ID:SGTC_723|Compound:4182-0001|FD-Score:9.09|P-value:4.33E-5 ID:SGTC_737|Compound:1950-0117|FD-Score:8.10|P-value:2.45E-4 ID:SGTC_748|Compound:0136-0228|FD-Score:9.04|P-value:4.70E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:9.87|P-value:9.61E-6 ID:SGTC_768|Compound:0384-0033|FD-Score:8.24|P-value:1.97E-4 ID:SGTC_813|Compound:k007-0158|FD-Score:8.06|P-value:2.63E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:19.10|P-value:2.07E-17 ID:SGTC_823|Compound:0417-1665|FD-Score:18.30|P-value:4.06E-16 ID:SGTC_826|Compound:1683-5028|FD-Score:10.60|P-value:2.16E-6 ID:SGTC_844|Compound:0330-0132|FD-Score:8.03|P-value:2.80E-4 ID:SGTC_860|Compound:0443-0016|FD-Score:9.87|P-value:9.54E-6 ID:SGTC_903|Compound:1134-0042|FD-Score:11.60|P-value:2.46E-7 ID:SGTC_926|Compound:2268-1401|FD-Score:11.20|P-value:6.06E-7 ID:SGTC_933|Compound:2914-0560|FD-Score:8.53|P-value:1.17E-4 ID:SGTC_981|Compound:1488-1094|FD-Score:8.69|P-value:8.85E-5 ID:SGTC_1011|Compound:4112-3381|FD-Score:10.60|P-value:1.97E-6 ID:SGTC_1041|Compound:0206-0046|FD-Score:11.10|P-value:7.14E-7 ID:SGTC_1047|Compound:2043-3044|FD-Score:12.20|P-value:5.20E-8 ID:SGTC_1056|Compound:3448-1962|FD-Score:8.22|P-value:2.03E-4 ID:SGTC_1058|Compound:3448-5425|FD-Score:13.80|P-value:8.76E-10 ID:SGTC_1076|Compound:itraconazole|FD-Score:8.44|P-value:1.38E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:18.10|P-value:8.26E-16 ID:SGTC_1114|Compound:scopoletin|FD-Score:9.01|P-value:5.02E-5 ID:SGTC_1117|Compound:retinoic acid|FD-Score:8.34|P-value:1.65E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:13.90|P-value:6.39E-10 ID:SGTC_1131|Compound:3454-3128|FD-Score:10.10|P-value:6.23E-6 ID:SGTC_1156|Compound:4092-0367|FD-Score:7.86|P-value:3.67E-4 ID:SGTC_1159|Compound:4092-0538|FD-Score:12.60|P-value:1.81E-8 ID:SGTC_1160|Compound:4092-0570|FD-Score:11.70|P-value:1.73E-7 ID:SGTC_1161|Compound:k007-0610|FD-Score:12.40|P-value:2.95E-8 ID:SGTC_1172|Compound:0370-0043|FD-Score:8.84|P-value:6.84E-5 ID:SGTC_1181|Compound:1222-0449|FD-Score:12.60|P-value:1.86E-8 ID:SGTC_1189|Compound:1431-2119|FD-Score:12.80|P-value:1.05E-8 ID:SGTC_1193|Compound:1488-0126|FD-Score:22.80|P-value:4.12E-24 ID:SGTC_1194|Compound:1488-0194|FD-Score:23.40|P-value:2.29E-25 ID:SGTC_1213|Compound:1315-0166|FD-Score:9.27|P-value:3.09E-5 ID:SGTC_1304|Compound:1165-0502|FD-Score:9.21|P-value:3.46E-5 ID:SGTC_1313|Compound:1220-0047|FD-Score:8.04|P-value:2.75E-4 ID:SGTC_1427|Compound:4048-4900|FD-Score:13.20|P-value:3.66E-9 ID:SGTC_1455|Compound:4262-0120|FD-Score:9.22|P-value:3.41E-5 ID:SGTC_1457|Compound:k015-0032|FD-Score:7.60|P-value:5.53E-4 ID:SGTC_1474|Compound:0330-0125|FD-Score:10.20|P-value:5.15E-6 ID:SGTC_1482|Compound:3346-2049|FD-Score:20.80|P-value:2.66E-20 ID:SGTC_1494|Compound:4358-1428|FD-Score:14.70|P-value:5.92E-11 ID:SGTC_1496|Compound:4469-0713|FD-Score:16.40|P-value:3.64E-13 ID:SGTC_1520|Compound:flindersine|FD-Score:11.50|P-value:2.83E-7 ID:SGTC_1541|Compound:2',3',6-trimethoxyflavone|FD-Score:17.40|P-value:1.23E-14 ID:SGTC_1546|Compound:5-methoxyflavanone|FD-Score:14.60|P-value:9.28E-11 ID:SGTC_1548|Compound:st061468|FD-Score:7.61|P-value:5.49E-4 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:17.20|P-value:2.09E-14 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:8.08|P-value:2.56E-4 ID:SGTC_1595|Compound:6-ethoxy-3(4'-hydroxyphenyl)-4-methylcoumarin|FD-Score:9.61|P-value:1.60E-5 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:8.88|P-value:6.33E-5 ID:SGTC_1600|Compound:coumarin 106|FD-Score:8.03|P-value:2.76E-4 ID:SGTC_1601|Compound:4'-hydroxyflavanone|FD-Score:7.42|P-value:7.38E-4 ID:SGTC_1603|Compound:st002045|FD-Score:34.00|P-value:2.07E-51 ID:SGTC_1608|Compound:st001473|FD-Score:13.00|P-value:6.13E-9 ID:SGTC_1617|Compound:st002906|FD-Score:36.10|P-value:6.70E-58 ID:SGTC_1623|Compound:st003709|FD-Score:7.30|P-value:8.80E-4 ID:SGTC_1636|Compound:st007707|FD-Score:13.60|P-value:1.53E-9 ID:SGTC_1649|Compound:st011737|FD-Score:11.50|P-value:2.85E-7 ID:SGTC_1654|Compound:st012436|FD-Score:7.70|P-value:4.77E-4 ID:SGTC_1655|Compound:st012546|FD-Score:7.44|P-value:7.10E-4 ID:SGTC_1671|Compound:st016596|FD-Score:9.97|P-value:7.80E-6 ID:SGTC_1672|Compound:st016598|FD-Score:11.80|P-value:1.38E-7 ID:SGTC_1673|Compound:st016611|FD-Score:20.20|P-value:3.53E-19 ID:SGTC_1697|Compound:st025554|FD-Score:8.37|P-value:1.55E-4 ID:SGTC_1699|Compound:st031318|FD-Score:11.90|P-value:1.03E-7 ID:SGTC_1710|Compound:st031758|FD-Score:8.84|P-value:6.83E-5 ID:SGTC_1715|Compound:st032160|FD-Score:7.69|P-value:4.82E-4 ID:SGTC_1720|Compound:st037298|FD-Score:7.88|P-value:3.53E-4 ID:SGTC_1750|Compound:st081859|FD-Score:7.44|P-value:7.13E-4 ID:SGTC_1778|Compound:st046819|FD-Score:8.14|P-value:2.30E-4 ID:SGTC_1797|Compound:st048695|FD-Score:12.40|P-value:2.97E-8 ID:SGTC_1824|Compound:st053723|FD-Score:18.80|P-value:6.17E-17 ID:SGTC_1833|Compound:st055984|FD-Score:7.69|P-value:4.85E-4 ID:SGTC_1835|Compound:st008666|FD-Score:11.90|P-value:1.04E-7 ID:SGTC_1837|Compound:st055472|FD-Score:7.23|P-value:9.86E-4 ID:SGTC_1838|Compound:st055369|FD-Score:9.56|P-value:1.76E-5 ID:SGTC_1847|Compound:st056231|FD-Score:8.40|P-value:1.47E-4 ID:SGTC_1865|Compound:st057639|FD-Score:8.28|P-value:1.84E-4 ID:SGTC_1868|Compound:st057644|FD-Score:9.57|P-value:1.72E-5 ID:SGTC_1881|Compound:5652484|FD-Score:14.90|P-value:3.60E-11 ID:SGTC_1882|Compound:5615643|FD-Score:14.10|P-value:3.44E-10 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:20.80|P-value:3.08E-20 ID:SGTC_1909|Compound:st060837|FD-Score:23.20|P-value:5.93E-25 ID:SGTC_1921|Compound:5740136|FD-Score:7.52|P-value:6.31E-4 ID:SGTC_1933|Compound:st074711|FD-Score:8.55|P-value:1.15E-4 ID:SGTC_1937|Compound:st074714|FD-Score:9.62|P-value:1.57E-5 ID:SGTC_1952|Compound:st077036|FD-Score:8.42|P-value:1.42E-4 ID:SGTC_1972|Compound:st070201|FD-Score:12.50|P-value:2.23E-8 ID:SGTC_1975|Compound:st070967|FD-Score:22.00|P-value:1.30E-22 ID:SGTC_1999|Compound:st074831|FD-Score:11.40|P-value:3.38E-7 ID:SGTC_2024|Compound:5144227|FD-Score:12.00|P-value:9.38E-8 ID:SGTC_2036|Compound:5160441|FD-Score:11.60|P-value:2.11E-7 ID:SGTC_2038|Compound:4100038|FD-Score:21.80|P-value:3.55E-22 ID:SGTC_2056|Compound:5235370|FD-Score:11.20|P-value:5.09E-7 ID:SGTC_2064|Compound:5220758|FD-Score:7.33|P-value:8.50E-4 ID:SGTC_2093|Compound:5331342|FD-Score:13.60|P-value:1.42E-9 ID:SGTC_2094|Compound:5332512|FD-Score:9.98|P-value:7.61E-6 ID:SGTC_2122|Compound:5258151|FD-Score:9.67|P-value:1.42E-5 ID:SGTC_2137|Compound:5261020|FD-Score:12.10|P-value:7.15E-8 ID:SGTC_2148|Compound:5546263|FD-Score:8.57|P-value:1.09E-4 ID:SGTC_2168|Compound:5727979|FD-Score:9.23|P-value:3.32E-5 ID:SGTC_2175|Compound:5807670|FD-Score:10.20|P-value:4.74E-6 ID:SGTC_2197|Compound:6588183|FD-Score:20.90|P-value:1.89E-20 ID:SGTC_2198|Compound:6589944|FD-Score:11.70|P-value:1.67E-7 ID:SGTC_2203|Compound:7227154|FD-Score:10.60|P-value:2.09E-6 ID:SGTC_2224|Compound:6650123|FD-Score:8.81|P-value:7.13E-5 ID:SGTC_2231|Compound:micatex|FD-Score:12.20|P-value:5.70E-8 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:25.20|P-value:4.42E-29 ID:SGTC_2233|Compound:sulbentine|FD-Score:9.43|P-value:2.28E-5 ID:SGTC_2249|Compound:haloperidol|FD-Score:11.40|P-value:3.65E-7 ID:SGTC_2254|Compound:7938975|FD-Score:35.20|P-value:3.85E-55 ID:SGTC_2255|Compound:7941087|FD-Score:11.00|P-value:9.56E-7 ID:SGTC_2267|Compound:7931562|FD-Score:11.50|P-value:2.58E-7 ID:SGTC_2268|Compound:7933382|FD-Score:7.74|P-value:4.47E-4 ID:SGTC_2273|Compound:7815444|FD-Score:8.10|P-value:2.45E-4 ID:SGTC_2296|Compound:7971656|FD-Score:20.50|P-value:1.07E-19 ID:SGTC_2299|Compound:7976368|FD-Score:10.40|P-value:3.20E-6 ID:SGTC_2301|Compound:7769476|FD-Score:14.40|P-value:1.46E-10 ID:SGTC_2304|Compound:7443016|FD-Score:10.30|P-value:3.74E-6 ID:SGTC_2312|Compound:7706453|FD-Score:12.30|P-value:3.95E-8 ID:SGTC_2376|Compound:9072922|FD-Score:10.20|P-value:4.90E-6 ID:SGTC_2377|Compound:9073351|FD-Score:8.01|P-value:2.85E-4 ID:SGTC_2384|Compound:9036245|FD-Score:12.90|P-value:9.36E-9 ID:SGTC_2408|Compound:sulbentine|FD-Score:11.20|P-value:5.13E-7 ID:SGTC_2409|Compound:alverine citrate|FD-Score:49.20|P-value:4.73E-106 ID:SGTC_2411|Compound:st077133|FD-Score:9.06|P-value:4.57E-5 ID:SGTC_2413|Compound:inermin|FD-Score:9.42|P-value:2.29E-5 ID:SGTC_2416|Compound:tofa|FD-Score:12.80|P-value:1.30E-8 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:9.49|P-value:2.01E-5 ID:SGTC_2472|Compound:5377652|FD-Score:12.30|P-value:4.40E-8 ID:SGTC_2478|Compound:5763493|FD-Score:16.20|P-value:5.62E-13 ID:SGTC_2486|Compound:5283202|FD-Score:16.10|P-value:8.85E-13 ID:SGTC_2488|Compound:5268135|FD-Score:17.60|P-value:5.56E-15 ID:SGTC_2501|Compound:sodium tetradecyl sulfate|FD-Score:9.08|P-value:4.38E-5 ID:SGTC_2508|Compound:celastrol|FD-Score:7.36|P-value:8.05E-4 ID:SGTC_2523|Compound:spermine|FD-Score:8.92|P-value:5.86E-5 ID:SGTC_2524|Compound:avocatin b|FD-Score:9.48|P-value:2.04E-5 ID:SGTC_2527|Compound:2',3'-dihydroxy-4-methoxy-4'-ethoxybenzophenone|FD-Score:8.00|P-value:2.92E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:17.80|P-value:3.09E-15 ID:SGTC_2554|Compound:13-methyl-4,4-bisnor-8,11,13-podocarpatrien-3-one|FD-Score:7.65|P-value:5.13E-4 ID:SGTC_2607|Compound:solasodine|FD-Score:37.30|P-value:9.13E-62 ID:SGTC_2616|Compound:abietic acid|FD-Score:15.10|P-value:2.13E-11 ID:SGTC_2618|Compound:avocadyne|FD-Score:30.20|P-value:3.91E-41 ID:SGTC_2620|Compound:irigenin|FD-Score:11.90|P-value:1.00E-7 ID:SGTC_2636|Compound:apigenin dimethyl ether|FD-Score:13.20|P-value:4.20E-9 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:10.10|P-value:5.97E-6 ID:SGTC_2650|Compound:prasterone|FD-Score:8.23|P-value:2.00E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.59|P-value:1.06E-4 ID:SGTC_2669|Compound:eugenol|FD-Score:9.64|P-value:1.52E-5 ID:SGTC_2683|Compound:piperine|FD-Score:10.30|P-value:3.71E-6 ID:SGTC_2684|Compound:capsaicin|FD-Score:10.50|P-value:2.70E-6 ID:SGTC_2699|Compound:st077704|FD-Score:14.80|P-value:4.46E-11 ID:SGTC_2725|Compound:haloperidol|FD-Score:14.50|P-value:1.26E-10 ID:SGTC_2741|Compound:miltefosine|FD-Score:7.48|P-value:6.70E-4 ID:SGTC_2752|Compound:diclazuril|FD-Score:30.20|P-value:5.97E-41 ID:SGTC_2757|Compound:clomiphene|FD-Score:10.40|P-value:3.09E-6 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:27.10|P-value:2.87E-33 ID:SGTC_2776|Compound:terbinafine|FD-Score:19.40|P-value:6.52E-18 ID:SGTC_2777|Compound:climbazole|FD-Score:12.80|P-value:1.17E-8 ID:SGTC_2778|Compound:tioconazole|FD-Score:20.70|P-value:3.54E-20 ID:SGTC_2816|Compound:7982706|FD-Score:9.05|P-value:4.64E-5 ID:SGTC_2852|Compound:9023854|FD-Score:10.60|P-value:1.99E-6 ID:SGTC_2862|Compound:9027634|FD-Score:-7.51|P-value:2.37E-4 ID:SGTC_2880|Compound:9042983|FD-Score:10.40|P-value:2.99E-6 ID:SGTC_2910|Compound:7948405|FD-Score:8.01|P-value:2.88E-4 ID:SGTC_2921|Compound:7974240|FD-Score:7.80|P-value:4.05E-4 ID:SGTC_2939|Compound:9044578|FD-Score:18.20|P-value:5.36E-16 ID:SGTC_2948|Compound:9070189|FD-Score:11.20|P-value:5.78E-7 ID:SGTC_3018|Compound:9082602|FD-Score:28.70|P-value:2.59E-37 ID:SGTC_3060|Compound:1327-0027|FD-Score:8.40|P-value:1.48E-4 ID:SGTC_3283|Compound:9109332|FD-Score:-9.15|P-value:1.18E-5 ID:SGTC_3308|Compound:9128332|FD-Score:30.40|P-value:1.24E-41 ID:SGTC_3317|Compound:9138495|FD-Score:7.74|P-value:4.46E-4 ID:SGTC_3318|Compound:9139014|FD-Score:10.40|P-value:3.26E-6

Top fitness defect scores for YKL211C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2409 alverine citrate 49.20 64.0 µM 4.73E-106 1 0
2 SGTC_2607 solasodine 37.30 47.4 µM 9.13E-62 2 4.51E-305
3 SGTC_1617 st002906 36.10 78.0 µM 6.70E-58 1 1.28E-285
4 SGTC_2254 7938975 35.20 95.2 µM 3.85E-55 1 9.89E-272
5 SGTC_1603 st002045 34.00 67.8 µM 2.07E-51 TSC3-RPN4 2 5.95E-253
6 SGTC_3308 9128332 30.40 17.6 µM 1.24E-41 plasma membrane duress 2 9.93E-204
7 SGTC_2618 avocadyne 30.20 43.4 µM 3.91E-41 2 3.21E-201
8 SGTC_2752 diclazuril 30.20 33.1 µM 5.97E-41 1 2.69E-200
9 SGTC_3018 9082602 28.70 49.5 µM 2.59E-37 1 5.54E-182
10 SGTC_2758 dehydroepiandrosterone 27.10 69.3 µM 2.87E-33 1 1.29E-161
11 SGTC_2232 chlorophetanol 25.20 41.5 µM 4.42E-29 TRP & mitochondrial translation 1 1.56E-140
12 SGTC_1194 1488-0194 23.40 225.0 µM 2.29E-25 1 7.81E-122
13 SGTC_1909 st060837 23.20 51.5 µM 5.93E-25 1 9.49E-120
14 SGTC_1193 1488-0126 22.80 41.5 µM 4.12E-24 1 1.63E-115
15 SGTC_1975 st070967 22.00 30.8 µM 1.30E-22 1 5.71E-108
16 SGTC_2038 4100038 21.80 31.0 µM 3.55E-22 plasma membrane duress 5 9.13E-106
17 SGTC_2197 6588183 20.90 93.1 µM 1.89E-20 1 4.38E-97
18 SGTC_1482 3346-2049 20.80 8.5 µM 2.66E-20 1 2.48E-96
19 SGTC_1883 5-benzylidenerhodanine 20.80 20.0 µM 3.08E-20 TRP & mitochondrial translation 5 5.14E-96
20 SGTC_2778 tioconazole 20.70 65.1 nM 3.54E-20 ergosterol depletion effects on membrane 1 1.04E-95

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.768 0 YER090W TRP2 hom Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p
0.734 0 YDR008C_d YDR008C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.717 0 YDR354W TRP4 hom Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
0.704 0 YDR007W TRP1 hom Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
0.606 0 YGL026C TRP5 hom Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis
0.583 1.55E-303 YEL009C GCN4 hom Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
0.576 5.87E-294 YDR127W ARO1 hom Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
0.541 4.26E-253 YDR283C GCN2 hom Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control
0.491 2.54E-202 YKR026C GCN3 hom Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
0.485 1.62E-196 YDR035W ARO3 hom 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan
0.437 7.62E-156 YGL117W_p YGL117W_p hom Putative protein of unknown function
0.402 4.85E-130 YFR009W GCN20 hom Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA
0.388 1.75E-120 YGL148W ARO2 hom Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress
0.232 3.24E-42 YIR023W DAL81 hom Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
0.170 4.39E-23 YMR071C TVP18 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments