HIPHOP chemogenomics database
YKR058W / GLG1 
Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG1 has a paralog, GLG2, that arose from the whole genome duplication
Zygosity: Homozygous strain
fixedexpanded
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Top fitness defect scores for YKR058W deletion by condition
Download Fitness data (tab-delimited text) (excel) |
Cofit Genes
Download Cofitness data (tab-delimited text) (excel)| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|---|---|---|---|---|
| 0.162 | 4.93E-21 | YBL086C_p | YBL086C_p | hom | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery |
| 0.149 | 3.65E-18 | YKL202W_d | YKL202W_d | hom | Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
| 0.128 | 1.01E-13 | YJR019C | TES1 | hom | Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids |
| 0.123 | 7.44E-13 | YDR122W | KIN1 | hom | Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p |
| 0.119 | 4.22E-12 | YDR094W_d | YDR094W_d | hom | Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2 |
| 0.115 | 2.61E-11 | YJL122W | ALB1 | hom | Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p |
| 0.115 | 2.95E-11 | YKL131W_d | YKL131W_d | hom | Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data |
| 0.112 | 9.09E-11 | YCR105W | ADH7 | hom | NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance |
| 0.111 | 9.70E-11 | YER064C | VHR2 | hom | Non-essential nuclear protein; null mutation has global effects on transcription; VHR2 has a paralog, VHR1, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress |
| 0.111 | 1.16E-10 | YER068C-A_d | YER068C-A_d | hom | Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
| 0.109 | 2.24E-10 | YMR305C | SCW10 | hom | Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p |
| 0.108 | 3.28E-10 | YGR149W_p | YGR149W_p | hom | Putative protein of unknown function; predicted to be an integal membrane protein |
| 0.108 | 3.42E-10 | YKR039W | GAP1 | hom | General amino acid permease; Gap1p senses the presence of amino acid substrates to regulate localization to the plasma membrane when needed; essential for invasive growth |
| 0.108 | 4.00E-10 | YFL041W | FET5 | hom | Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport |
| 0.107 | 6.44E-10 | YER071C_p | TDA2_p | hom | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; null mutant is sensitive to expression of the top1-T722A allele |