Mitochondrial ribosomal protein of the large subunit
Zygosity: Homozygous strain

Cofit Genes
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Correlation | pval | ORF | Gene | Zygosity | Description |
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0.476 |
1.16E-188 |
YMR287C |
DSS1 |
hom |
3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs |
0.464 |
2.49E-178 |
YLR260W |
LCB5 |
hom |
Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules |
0.460 |
1.34E-175 |
YNL252C |
MRPL17 |
hom |
Mitochondrial ribosomal protein of the large subunit |
0.457 |
3.48E-173 |
YPL078C |
ATP4 |
hom |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; contributes to the oligomerization of the complex; phosphorylated |
0.452 |
8.98E-169 |
YNL081C |
SWS2 |
hom |
Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency |
0.450 |
3.18E-167 |
YMR228W |
MTF1 |
hom |
Mitochondrial RNA polymerase specificity factor; has structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation |
0.449 |
2.40E-166 |
YCR024C |
SLM5 |
hom |
Mitochondrial asparaginyl-tRNA synthetase |
0.446 |
5.01E-164 |
YMR193W |
MRPL24 |
hom |
Mitochondrial ribosomal protein of the large subunit; two mitochondrial ribosomal proteins, YmL14 and YmL24, have been assigned to the same gene |
0.437 |
2.06E-156 |
YDR462W |
MRPL28 |
hom |
Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress |
0.437 |
2.65E-156 |
YGR220C |
MRPL9 |
hom |
Mitochondrial ribosomal protein of the large subunit |
0.435 |
7.92E-155 |
YER087W |
AIM10 |
hom |
Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant is viable and displays elevated frequency of mitochondrial genome loss |
0.435 |
1.11E-154 |
YDR509W_d |
YDR509W_d |
hom |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
0.434 |
3.40E-154 |
YPL040C |
ISM1 |
hom |
Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth |
0.424 |
9.33E-147 |
YPR166C |
MRP2 |
hom |
Mitochondrial ribosomal protein of the small subunit |
0.421 |
4.42E-144 |
YLL033W |
IRC19 |
hom |
Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci |