YNL275W / BOR1

Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1

Zygosity: Homozygous strain
fixedexpanded
Profile for YNL275W / BOR1

Click on Significant Values for Screen Details ID:SGTC_67|Compound:0335-0847|FD-Score:-5.72|P-value:6.83E-9 ID:SGTC_177|Compound:1327-0068|FD-Score:3.70|P-value:1.02E-4 ID:SGTC_363|Compound:0455-0021|FD-Score:3.76|P-value:7.90E-5 ID:SGTC_371|Compound:0195-0006|FD-Score:4.06|P-value:2.29E-5 ID:SGTC_411|Compound:enrofloxacin|FD-Score:4.36|P-value:6.09E-6 ID:SGTC_667|Compound:1498-1044|FD-Score:3.10|P-value:9.13E-4 ID:SGTC_701|Compound:4424-0219|FD-Score:-3.34|P-value:4.72E-4 ID:SGTC_702|Compound:1488-0190|FD-Score:-3.68|P-value:1.35E-4 ID:SGTC_796|Compound:1234-0020|FD-Score:3.30|P-value:4.54E-4 ID:SGTC_870|Compound:0573-2213|FD-Score:4.41|P-value:4.86E-6 ID:SGTC_1028|Compound:k015-0029|FD-Score:3.48|P-value:2.39E-4 ID:SGTC_1035|Compound:k081-0041|FD-Score:4.09|P-value:2.06E-5 ID:SGTC_1039|Compound:k821-0043|FD-Score:-3.79|P-value:8.75E-5 ID:SGTC_1056|Compound:3448-1962|FD-Score:3.18|P-value:6.93E-4 ID:SGTC_1073|Compound:triclabendazole|FD-Score:3.11|P-value:8.96E-4 ID:SGTC_1677|Compound:st019204|FD-Score:3.36|P-value:3.76E-4 ID:SGTC_1765|Compound:st044815|FD-Score:3.53|P-value:1.98E-4 ID:SGTC_1807|Compound:st050092|FD-Score:3.36|P-value:3.71E-4 ID:SGTC_1846|Compound:st056244|FD-Score:3.49|P-value:2.26E-4 ID:SGTC_1924|Compound:st058459|FD-Score:-3.25|P-value:6.45E-4 ID:SGTC_2006|Compound:4011487|FD-Score:3.56|P-value:1.73E-4 ID:SGTC_2060|Compound:5238662|FD-Score:4.34|P-value:6.86E-6 ID:SGTC_2095|Compound:5432005|FD-Score:3.41|P-value:3.04E-4 ID:SGTC_2126|Compound:5251174|FD-Score:-4.19|P-value:1.61E-5 ID:SGTC_2202|Compound:7226349|FD-Score:3.55|P-value:1.81E-4 ID:SGTC_2358|Compound:9037157|FD-Score:-3.41|P-value:3.72E-4 ID:SGTC_2379|Compound:9035213|FD-Score:-3.21|P-value:7.39E-4 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:3.75|P-value:8.24E-5 ID:SGTC_2498|Compound:4'-Methoxychalcone|FD-Score:3.30|P-value:4.52E-4 ID:SGTC_2756|Compound:carbadox|FD-Score:3.37|P-value:3.50E-4 ID:SGTC_2809|Compound:7964133|FD-Score:3.63|P-value:1.33E-4 ID:SGTC_2908|Compound:7930301|FD-Score:5.74|P-value:4.41E-9 ID:SGTC_2910|Compound:7948405|FD-Score:4.96|P-value:3.39E-7 ID:SGTC_2917|Compound:7979103|FD-Score:6.01|P-value:8.88E-10 ID:SGTC_2927|Compound:9011802|FD-Score:3.33|P-value:4.06E-4 ID:SGTC_3012|Compound:9080433|FD-Score:-3.71|P-value:1.20E-4 ID:SGTC_3179|Compound:9107801|FD-Score:3.16|P-value:7.50E-4 ID:SGTC_3277|Compound:9138724|FD-Score:3.11|P-value:8.95E-4 ID:SGTC_67|Compound:0335-0847|FD-Score:-5.72|P-value:6.83E-9 ID:SGTC_177|Compound:1327-0068|FD-Score:3.70|P-value:1.02E-4 ID:SGTC_363|Compound:0455-0021|FD-Score:3.76|P-value:7.90E-5 ID:SGTC_371|Compound:0195-0006|FD-Score:4.06|P-value:2.29E-5 ID:SGTC_411|Compound:enrofloxacin|FD-Score:4.36|P-value:6.09E-6 ID:SGTC_667|Compound:1498-1044|FD-Score:3.10|P-value:9.13E-4 ID:SGTC_701|Compound:4424-0219|FD-Score:-3.34|P-value:4.72E-4 ID:SGTC_702|Compound:1488-0190|FD-Score:-3.68|P-value:1.35E-4 ID:SGTC_796|Compound:1234-0020|FD-Score:3.30|P-value:4.54E-4 ID:SGTC_870|Compound:0573-2213|FD-Score:4.41|P-value:4.86E-6 ID:SGTC_1028|Compound:k015-0029|FD-Score:3.48|P-value:2.39E-4 ID:SGTC_1035|Compound:k081-0041|FD-Score:4.09|P-value:2.06E-5 ID:SGTC_1039|Compound:k821-0043|FD-Score:-3.79|P-value:8.75E-5 ID:SGTC_1056|Compound:3448-1962|FD-Score:3.18|P-value:6.93E-4 ID:SGTC_1073|Compound:triclabendazole|FD-Score:3.11|P-value:8.96E-4 ID:SGTC_1677|Compound:st019204|FD-Score:3.36|P-value:3.76E-4 ID:SGTC_1765|Compound:st044815|FD-Score:3.53|P-value:1.98E-4 ID:SGTC_1807|Compound:st050092|FD-Score:3.36|P-value:3.71E-4 ID:SGTC_1846|Compound:st056244|FD-Score:3.49|P-value:2.26E-4 ID:SGTC_1924|Compound:st058459|FD-Score:-3.25|P-value:6.45E-4 ID:SGTC_2006|Compound:4011487|FD-Score:3.56|P-value:1.73E-4 ID:SGTC_2060|Compound:5238662|FD-Score:4.34|P-value:6.86E-6 ID:SGTC_2095|Compound:5432005|FD-Score:3.41|P-value:3.04E-4 ID:SGTC_2126|Compound:5251174|FD-Score:-4.19|P-value:1.61E-5 ID:SGTC_2202|Compound:7226349|FD-Score:3.55|P-value:1.81E-4 ID:SGTC_2358|Compound:9037157|FD-Score:-3.41|P-value:3.72E-4 ID:SGTC_2379|Compound:9035213|FD-Score:-3.21|P-value:7.39E-4 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:3.75|P-value:8.24E-5 ID:SGTC_2498|Compound:4'-Methoxychalcone|FD-Score:3.30|P-value:4.52E-4 ID:SGTC_2756|Compound:carbadox|FD-Score:3.37|P-value:3.50E-4 ID:SGTC_2809|Compound:7964133|FD-Score:3.63|P-value:1.33E-4 ID:SGTC_2908|Compound:7930301|FD-Score:5.74|P-value:4.41E-9 ID:SGTC_2910|Compound:7948405|FD-Score:4.96|P-value:3.39E-7 ID:SGTC_2917|Compound:7979103|FD-Score:6.01|P-value:8.88E-10 ID:SGTC_2927|Compound:9011802|FD-Score:3.33|P-value:4.06E-4 ID:SGTC_3012|Compound:9080433|FD-Score:-3.71|P-value:1.20E-4 ID:SGTC_3179|Compound:9107801|FD-Score:3.16|P-value:7.50E-4 ID:SGTC_3277|Compound:9138724|FD-Score:3.11|P-value:8.95E-4

Top fitness defect scores for YNL275W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2917 7979103 6.01 53.8 µM 8.88E-10 3 9.26E-10
2 SGTC_2908 7930301 5.74 100.0 µM 4.41E-9 4 4.61E-9
3 SGTC_2910 7948405 4.96 26.0 µM 3.39E-7 plasma membrane duress 14 3.57E-7
4 SGTC_870 0573-2213 4.41 57.6 µM 4.86E-6 ERG2 11 5.12E-6
5 SGTC_411 enrofloxacin 4.36 100.0 µM 6.09E-6 DNA damage response 5 6.42E-6
6 SGTC_2060 5238662 4.34 140.0 µM 6.86E-6 21 7.23E-6
7 SGTC_1035 k081-0041 4.09 55.2 µM 2.06E-5 Golgi 20 2.17E-5
8 SGTC_371 0195-0006 4.06 7.4 µM 2.29E-5 18 2.42E-5
9 SGTC_363 0455-0021 3.76 3.1 µM 7.90E-5 azole & statin 71 8.33E-5
10 SGTC_2496 diffractaic acid 3.75 79.8 µM 8.24E-5 22 8.69E-5
11 SGTC_177 1327-0068 3.70 8.4 µM 1.02E-4 48 1.07E-4
12 SGTC_2809 7964133 3.63 13.0 µM 1.33E-4 60S ribosome export 48 1.40E-4
13 SGTC_2006 4011487 3.56 200.0 µM 1.73E-4 endomembrane recycling 100 1.83E-4
14 SGTC_2202 7226349 3.55 200.0 µM 1.81E-4 16 1.91E-4
15 SGTC_1765 st044815 3.53 90.4 µM 1.98E-4 37 2.08E-4
16 SGTC_1846 st056244 3.49 14.8 µM 2.26E-4 51 2.39E-4
17 SGTC_1028 k015-0029 3.48 4.8 µM 2.39E-4 40 2.52E-4
18 SGTC_2095 5432005 3.41 200.0 µM 3.04E-4 29 3.21E-4
19 SGTC_2756 carbadox 3.37 75.1 µM 3.50E-4 80 3.69E-4
20 SGTC_1807 st050092 3.36 58.9 µM 3.71E-4 60S ribosome export 27 3.91E-4

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.087 4.96E-7 YER067C-A_d YER067C-A_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YER067W
0.082 2.06E-6 YHR152W SPO12 hom Nucleolar protein of unknown function, positive regulator of mitotic exit; involved in regulating release of Cdc14p from the nucleolus in early anaphase, may play similar role in meiosis
0.081 2.39E-6 YNL266W_d YNL266W_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF IST1/YNL265C
0.080 3.34E-6 YIL112W HOS4 hom Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
0.079 5.13E-6 YDR084C TVP23 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
0.078 5.45E-6 YHR193C EGD2 hom Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes
0.074 1.69E-5 YNR048W YNR048W hom Protein that interacts with phospholipid translocase (flippase) Dnf3p; YNR048W has a paralog, CDC50, that arose from the whole genome duplication
0.072 2.78E-5 YJR139C HOM6 hom Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions
0.072 3.10E-5 YOR277C_d YOR277C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene CAF20
0.072 3.22E-5 YPL260W YPL260W hom Putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene; protein abundance increases in response to DNA replication stress
0.069 6.76E-5 YCL011C GBP2 hom Poly(A+) RNA-binding protein; involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Npl3p; also binds single-stranded telomeric repeat sequence in vitro; GBP2 has a paralog, HRB1, that arose from the whole genome duplication
0.068 8.06E-5 YDR258C HSP78 hom Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; able to prevent the aggregation of misfolded proteins as well as resolubilize protein aggregates
0.068 8.46E-5 YDL062W_d YDL062W_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps uncharacterized ORF YDL063C; YDL062W is not essential
0.067 1.02E-4 YGR170W PSD2 hom Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine
0.067 1.03E-4 YLL061W MMP1 hom High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p