YOR207C / RET1

Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs

Zygosity: Heterozygous strain
fixedexpanded
Profile for YOR207C / RET1

Click on Significant Values for Screen Details ID:SGTC_87|Compound:0100-0052|FD-Score:9.93|P-value:1.43E-23 ID:SGTC_127|Compound:0180-0333|FD-Score:-5.45|P-value:6.61E-8 ID:SGTC_133|Compound:0724-0033|FD-Score:4.14|P-value:1.25E-5 ID:SGTC_136|Compound:0097-0015|FD-Score:5.08|P-value:1.36E-7 ID:SGTC_138|Compound:0850-0259|FD-Score:4.26|P-value:7.43E-6 ID:SGTC_141|Compound:0443-0274|FD-Score:-11.70|P-value:7.56E-31 ID:SGTC_159|Compound:3970-0959|FD-Score:3.65|P-value:9.60E-5 ID:SGTC_168|Compound:3970-0862|FD-Score:3.50|P-value:1.75E-4 ID:SGTC_177|Compound:1327-0068|FD-Score:24.40|P-value:2.47E-130 ID:SGTC_179|Compound:1273-0063|FD-Score:3.15|P-value:6.17E-4 ID:SGTC_184|Compound:1494-0393|FD-Score:4.93|P-value:2.90E-7 ID:SGTC_210|Compound:3551-0445|FD-Score:33.00|P-value:2.70E-235 ID:SGTC_392|Compound:N-ethylmaleimide|FD-Score:5.02|P-value:1.87E-7 ID:SGTC_428|Compound:3448-4153|FD-Score:4.09|P-value:1.58E-5 ID:SGTC_461|Compound:N-acetylfarnesylcysteine|FD-Score:-3.93|P-value:8.03E-5 ID:SGTC_503|Compound:tyrphostin 8|FD-Score:15.00|P-value:1.20E-50 ID:SGTC_540|Compound:1187-0821|FD-Score:3.54|P-value:1.51E-4 ID:SGTC_548|Compound:1436-0017|FD-Score:3.73|P-value:7.09E-5 ID:SGTC_589|Compound:1227-0070|FD-Score:8.41|P-value:1.67E-17 ID:SGTC_594|Compound:1487-1584|FD-Score:3.90|P-value:3.51E-5 ID:SGTC_611|Compound:3453-1652|FD-Score:15.00|P-value:3.69E-51 ID:SGTC_625|Compound:k213-0058|FD-Score:3.29|P-value:3.80E-4 ID:SGTC_673|Compound:1082-0474|FD-Score:3.79|P-value:5.46E-5 ID:SGTC_682|Compound:0kpi-0099|FD-Score:3.32|P-value:3.36E-4 ID:SGTC_735|Compound:3076-0345|FD-Score:3.64|P-value:9.95E-5 ID:SGTC_785|Compound:1270-0111|FD-Score:3.04|P-value:8.81E-4 ID:SGTC_800|Compound:3448-7362|FD-Score:3.70|P-value:8.05E-5 ID:SGTC_820|Compound:1582-0060|FD-Score:9.11|P-value:3.27E-20 ID:SGTC_828|Compound:2074-0507|FD-Score:3.09|P-value:7.44E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:19.60|P-value:8.77E-85 ID:SGTC_831|Compound:k061-1017|FD-Score:4.91|P-value:3.21E-7 ID:SGTC_832|Compound:4083-0019|FD-Score:5.07|P-value:1.42E-7 ID:SGTC_839|Compound:0122-0028|FD-Score:5.41|P-value:2.28E-8 ID:SGTC_860|Compound:0443-0016|FD-Score:4.52|P-value:2.21E-6 ID:SGTC_897|Compound:1000-0139|FD-Score:11.70|P-value:4.19E-32 ID:SGTC_911|Compound:3456-4043|FD-Score:3.49|P-value:1.82E-4 ID:SGTC_961|Compound:1252-1571|FD-Score:3.11|P-value:7.12E-4 ID:SGTC_1024|Compound:4507-0395|FD-Score:4.92|P-value:3.04E-7 ID:SGTC_1042|Compound:0350-0096|FD-Score:3.08|P-value:7.73E-4 ID:SGTC_1050|Compound:3232-1156|FD-Score:3.37|P-value:2.79E-4 ID:SGTC_1073|Compound:triclabendazole|FD-Score:3.54|P-value:1.49E-4 ID:SGTC_1107|Compound:amlodipine|FD-Score:-4.57|P-value:5.22E-6 ID:SGTC_1168|Compound:k815-0004|FD-Score:5.32|P-value:3.69E-8 ID:SGTC_1179|Compound:1021-1431|FD-Score:8.08|P-value:2.54E-16 ID:SGTC_1190|Compound:1486-1332|FD-Score:-3.31|P-value:7.94E-4 ID:SGTC_1192|Compound:1488-0095|FD-Score:-3.59|P-value:2.88E-4 ID:SGTC_1200|Compound:1643-0193|FD-Score:3.18|P-value:5.56E-4 ID:SGTC_1256|Compound:0570-0116|FD-Score:3.47|P-value:1.92E-4 ID:SGTC_1304|Compound:1165-0502|FD-Score:-3.42|P-value:5.29E-4 ID:SGTC_1309|Compound:pyrazolanthrone|FD-Score:5.02|P-value:1.85E-7 ID:SGTC_1432|Compound:4049-0298|FD-Score:3.76|P-value:6.24E-5 ID:SGTC_1483|Compound:3453-0561|FD-Score:3.77|P-value:6.11E-5 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:12.80|P-value:1.09E-37 ID:SGTC_1527|Compound:coumarin|FD-Score:-3.31|P-value:7.95E-4 ID:SGTC_1534|Compound:6-azauridine|FD-Score:4.03|P-value:2.00E-5 ID:SGTC_1574|Compound:spiramycin|FD-Score:-4.12|P-value:3.76E-5 ID:SGTC_1634|Compound:st006576|FD-Score:10.60|P-value:1.38E-26 ID:SGTC_1642|Compound:st009582|FD-Score:5.53|P-value:1.16E-8 ID:SGTC_1643|Compound:st009866|FD-Score:28.10|P-value:9.71E-172 ID:SGTC_1661|Compound:st013063|FD-Score:9.03|P-value:7.01E-20 ID:SGTC_1677|Compound:st019204|FD-Score:6.92|P-value:1.67E-12 ID:SGTC_1681|Compound:tripelennamine|FD-Score:-3.69|P-value:2.02E-4 ID:SGTC_1762|Compound:st045503|FD-Score:6.60|P-value:1.52E-11 ID:SGTC_1834|Compound:st055981|FD-Score:4.32|P-value:5.77E-6 ID:SGTC_1863|Compound:st057641|FD-Score:3.55|P-value:1.42E-4 ID:SGTC_1909|Compound:st060837|FD-Score:-3.59|P-value:2.93E-4 ID:SGTC_1915|Compound:st067105|FD-Score:34.20|P-value:3.14E-253 ID:SGTC_1930|Compound:st074634|FD-Score:13.60|P-value:2.62E-42 ID:SGTC_2004|Compound:4023728|FD-Score:8.78|P-value:6.44E-19 ID:SGTC_2016|Compound:5121758|FD-Score:3.82|P-value:4.86E-5 ID:SGTC_2018|Compound:5133068|FD-Score:4.94|P-value:2.84E-7 ID:SGTC_2019|Compound:4016004|FD-Score:6.33|P-value:9.18E-11 ID:SGTC_2026|Compound:5148700|FD-Score:3.43|P-value:2.21E-4 ID:SGTC_2035|Compound:5154463|FD-Score:5.98|P-value:8.07E-10 ID:SGTC_2067|Compound:5224629|FD-Score:5.91|P-value:1.24E-9 ID:SGTC_2073|Compound:5212005|FD-Score:3.41|P-value:2.40E-4 ID:SGTC_2090|Compound:5301565|FD-Score:3.41|P-value:2.41E-4 ID:SGTC_2093|Compound:5331342|FD-Score:3.89|P-value:3.73E-5 ID:SGTC_2110|Compound:5483698|FD-Score:7.81|P-value:2.15E-15 ID:SGTC_2112|Compound:5488546|FD-Score:3.15|P-value:6.12E-4 ID:SGTC_2113|Compound:5491891|FD-Score:6.08|P-value:4.42E-10 ID:SGTC_2151|Compound:5563267|FD-Score:12.90|P-value:2.87E-38 ID:SGTC_2172|Compound:5754775|FD-Score:4.29|P-value:6.47E-6 ID:SGTC_2225|Compound:6654152|FD-Score:5.05|P-value:1.56E-7 ID:SGTC_2226|Compound:7298446|FD-Score:3.40|P-value:2.55E-4 ID:SGTC_2233|Compound:sulbentine|FD-Score:26.70|P-value:4.42E-156 ID:SGTC_2246|Compound:7293507|FD-Score:8.68|P-value:1.52E-18 ID:SGTC_2299|Compound:7976368|FD-Score:3.99|P-value:2.37E-5 ID:SGTC_2306|Compound:7482397|FD-Score:13.80|P-value:3.55E-43 ID:SGTC_2311|Compound:7694451|FD-Score:3.91|P-value:3.34E-5 ID:SGTC_2323|Compound:6148992|FD-Score:15.60|P-value:1.48E-54 ID:SGTC_2328|Compound:6201408|FD-Score:4.53|P-value:2.11E-6 ID:SGTC_2339|Compound:9000433|FD-Score:3.04|P-value:9.09E-4 ID:SGTC_2378|Compound:9074213|FD-Score:3.33|P-value:3.23E-4 ID:SGTC_2396|Compound:5342950|FD-Score:3.08|P-value:7.72E-4 ID:SGTC_2408|Compound:sulbentine|FD-Score:7.66|P-value:6.99E-15 ID:SGTC_2411|Compound:st077133|FD-Score:16.60|P-value:1.21E-61 ID:SGTC_2430|Compound:5571206|FD-Score:10.60|P-value:1.40E-26 ID:SGTC_2451|Compound:5856223|FD-Score:7.71|P-value:4.71E-15 ID:SGTC_2466|Compound:5983409|FD-Score:3.05|P-value:8.76E-4 ID:SGTC_2470|Compound:5664817|FD-Score:3.37|P-value:2.80E-4 ID:SGTC_2493|Compound:resveratrol|FD-Score:3.90|P-value:3.59E-5 ID:SGTC_2494|Compound:18-aminoabieta-8,11,13-triene sulfate|FD-Score:4.93|P-value:3.03E-7 ID:SGTC_2495|Compound:cafestol|FD-Score:3.97|P-value:2.64E-5 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:3.44|P-value:2.18E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:16.30|P-value:6.03E-60 ID:SGTC_2522|Compound:biochanin a|FD-Score:12.00|P-value:2.24E-33 ID:SGTC_2526|Compound:patulin|FD-Score:3.64|P-value:1.01E-4 ID:SGTC_2533|Compound:agelasine|FD-Score:3.31|P-value:3.55E-4 ID:SGTC_2544|Compound:sphondin|FD-Score:22.00|P-value:7.29E-107 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:3.21|P-value:4.98E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:-3.62|P-value:2.61E-4 ID:SGTC_2579|Compound:2',5'-dihydroxy-4-methoxychalcone|FD-Score:5.12|P-value:1.12E-7 ID:SGTC_2601|Compound:securinine|FD-Score:4.59|P-value:1.60E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:18.50|P-value:1.03E-75 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:3.22|P-value:4.76E-4 ID:SGTC_2721|Compound:ifenprodil|FD-Score:-3.47|P-value:4.55E-4 ID:SGTC_2738|Compound:aclarubicin|FD-Score:10.90|P-value:6.55E-28 ID:SGTC_2739|Compound:tacrine|FD-Score:-3.33|P-value:7.37E-4 ID:SGTC_2829|Compound:7992743|FD-Score:4.92|P-value:3.18E-7 ID:SGTC_2836|Compound:9010338|FD-Score:-4.38|P-value:1.23E-5 ID:SGTC_2837|Compound:9008476|FD-Score:3.89|P-value:3.63E-5 ID:SGTC_2921|Compound:7974240|FD-Score:15.50|P-value:2.12E-54 ID:SGTC_2947|Compound:9072639|FD-Score:6.85|P-value:2.64E-12 ID:SGTC_2949|Compound:9072542|FD-Score:4.44|P-value:3.33E-6 ID:SGTC_2952|Compound:9073731|FD-Score:7.66|P-value:7.26E-15 ID:SGTC_2989|Compound:9073649|FD-Score:3.75|P-value:6.59E-5 ID:SGTC_2993|Compound:9054257|FD-Score:-4.39|P-value:1.19E-5 ID:SGTC_3001|Compound:9076041|FD-Score:4.15|P-value:1.23E-5 ID:SGTC_3075|Compound:9116269|FD-Score:-3.43|P-value:5.09E-4 ID:SGTC_3139|Compound:9095020|FD-Score:3.63|P-value:1.04E-4 ID:SGTC_3141|Compound:9094609|FD-Score:-4.84|P-value:1.45E-6 ID:SGTC_3144|Compound:9087057|FD-Score:3.30|P-value:3.59E-4 ID:SGTC_3212|Compound:9128307|FD-Score:3.52|P-value:1.58E-4 ID:SGTC_3215|Compound:9129942|FD-Score:3.32|P-value:3.41E-4 ID:SGTC_3217|Compound:9129673|FD-Score:-3.26|P-value:9.42E-4 ID:SGTC_3223|Compound:9129970|FD-Score:4.64|P-value:1.24E-6 ID:SGTC_3236|Compound:9132701|FD-Score:4.35|P-value:5.02E-6 ID:SGTC_3247|Compound:9135149|FD-Score:5.26|P-value:5.26E-8 ID:SGTC_3264|Compound:9137442|FD-Score:6.53|P-value:2.32E-11 ID:SGTC_3271|Compound:9137798|FD-Score:6.78|P-value:4.37E-12 ID:SGTC_3282|Compound:9108498|FD-Score:9.83|P-value:3.74E-23 ID:SGTC_3317|Compound:9138495|FD-Score:12.10|P-value:3.89E-34 ID:SGTC_3355|Compound:9151058|FD-Score:3.45|P-value:2.06E-4 ID:SGTC_87|Compound:0100-0052|FD-Score:9.93|P-value:1.43E-23 ID:SGTC_127|Compound:0180-0333|FD-Score:-5.45|P-value:6.61E-8 ID:SGTC_133|Compound:0724-0033|FD-Score:4.14|P-value:1.25E-5 ID:SGTC_136|Compound:0097-0015|FD-Score:5.08|P-value:1.36E-7 ID:SGTC_138|Compound:0850-0259|FD-Score:4.26|P-value:7.43E-6 ID:SGTC_141|Compound:0443-0274|FD-Score:-11.70|P-value:7.56E-31 ID:SGTC_159|Compound:3970-0959|FD-Score:3.65|P-value:9.60E-5 ID:SGTC_168|Compound:3970-0862|FD-Score:3.50|P-value:1.75E-4 ID:SGTC_177|Compound:1327-0068|FD-Score:24.40|P-value:2.47E-130 ID:SGTC_179|Compound:1273-0063|FD-Score:3.15|P-value:6.17E-4 ID:SGTC_184|Compound:1494-0393|FD-Score:4.93|P-value:2.90E-7 ID:SGTC_210|Compound:3551-0445|FD-Score:33.00|P-value:2.70E-235 ID:SGTC_392|Compound:N-ethylmaleimide|FD-Score:5.02|P-value:1.87E-7 ID:SGTC_428|Compound:3448-4153|FD-Score:4.09|P-value:1.58E-5 ID:SGTC_461|Compound:N-acetylfarnesylcysteine|FD-Score:-3.93|P-value:8.03E-5 ID:SGTC_503|Compound:tyrphostin 8|FD-Score:15.00|P-value:1.20E-50 ID:SGTC_540|Compound:1187-0821|FD-Score:3.54|P-value:1.51E-4 ID:SGTC_548|Compound:1436-0017|FD-Score:3.73|P-value:7.09E-5 ID:SGTC_589|Compound:1227-0070|FD-Score:8.41|P-value:1.67E-17 ID:SGTC_594|Compound:1487-1584|FD-Score:3.90|P-value:3.51E-5 ID:SGTC_611|Compound:3453-1652|FD-Score:15.00|P-value:3.69E-51 ID:SGTC_625|Compound:k213-0058|FD-Score:3.29|P-value:3.80E-4 ID:SGTC_673|Compound:1082-0474|FD-Score:3.79|P-value:5.46E-5 ID:SGTC_682|Compound:0kpi-0099|FD-Score:3.32|P-value:3.36E-4 ID:SGTC_735|Compound:3076-0345|FD-Score:3.64|P-value:9.95E-5 ID:SGTC_785|Compound:1270-0111|FD-Score:3.04|P-value:8.81E-4 ID:SGTC_800|Compound:3448-7362|FD-Score:3.70|P-value:8.05E-5 ID:SGTC_820|Compound:1582-0060|FD-Score:9.11|P-value:3.27E-20 ID:SGTC_828|Compound:2074-0507|FD-Score:3.09|P-value:7.44E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:19.60|P-value:8.77E-85 ID:SGTC_831|Compound:k061-1017|FD-Score:4.91|P-value:3.21E-7 ID:SGTC_832|Compound:4083-0019|FD-Score:5.07|P-value:1.42E-7 ID:SGTC_839|Compound:0122-0028|FD-Score:5.41|P-value:2.28E-8 ID:SGTC_860|Compound:0443-0016|FD-Score:4.52|P-value:2.21E-6 ID:SGTC_897|Compound:1000-0139|FD-Score:11.70|P-value:4.19E-32 ID:SGTC_911|Compound:3456-4043|FD-Score:3.49|P-value:1.82E-4 ID:SGTC_961|Compound:1252-1571|FD-Score:3.11|P-value:7.12E-4 ID:SGTC_1024|Compound:4507-0395|FD-Score:4.92|P-value:3.04E-7 ID:SGTC_1042|Compound:0350-0096|FD-Score:3.08|P-value:7.73E-4 ID:SGTC_1050|Compound:3232-1156|FD-Score:3.37|P-value:2.79E-4 ID:SGTC_1073|Compound:triclabendazole|FD-Score:3.54|P-value:1.49E-4 ID:SGTC_1107|Compound:amlodipine|FD-Score:-4.57|P-value:5.22E-6 ID:SGTC_1168|Compound:k815-0004|FD-Score:5.32|P-value:3.69E-8 ID:SGTC_1179|Compound:1021-1431|FD-Score:8.08|P-value:2.54E-16 ID:SGTC_1190|Compound:1486-1332|FD-Score:-3.31|P-value:7.94E-4 ID:SGTC_1192|Compound:1488-0095|FD-Score:-3.59|P-value:2.88E-4 ID:SGTC_1200|Compound:1643-0193|FD-Score:3.18|P-value:5.56E-4 ID:SGTC_1256|Compound:0570-0116|FD-Score:3.47|P-value:1.92E-4 ID:SGTC_1304|Compound:1165-0502|FD-Score:-3.42|P-value:5.29E-4 ID:SGTC_1309|Compound:pyrazolanthrone|FD-Score:5.02|P-value:1.85E-7 ID:SGTC_1432|Compound:4049-0298|FD-Score:3.76|P-value:6.24E-5 ID:SGTC_1483|Compound:3453-0561|FD-Score:3.77|P-value:6.11E-5 ID:SGTC_1525|Compound:8-methoxypsoralen|FD-Score:12.80|P-value:1.09E-37 ID:SGTC_1527|Compound:coumarin|FD-Score:-3.31|P-value:7.95E-4 ID:SGTC_1534|Compound:6-azauridine|FD-Score:4.03|P-value:2.00E-5 ID:SGTC_1574|Compound:spiramycin|FD-Score:-4.12|P-value:3.76E-5 ID:SGTC_1634|Compound:st006576|FD-Score:10.60|P-value:1.38E-26 ID:SGTC_1642|Compound:st009582|FD-Score:5.53|P-value:1.16E-8 ID:SGTC_1643|Compound:st009866|FD-Score:28.10|P-value:9.71E-172 ID:SGTC_1661|Compound:st013063|FD-Score:9.03|P-value:7.01E-20 ID:SGTC_1677|Compound:st019204|FD-Score:6.92|P-value:1.67E-12 ID:SGTC_1681|Compound:tripelennamine|FD-Score:-3.69|P-value:2.02E-4 ID:SGTC_1762|Compound:st045503|FD-Score:6.60|P-value:1.52E-11 ID:SGTC_1834|Compound:st055981|FD-Score:4.32|P-value:5.77E-6 ID:SGTC_1863|Compound:st057641|FD-Score:3.55|P-value:1.42E-4 ID:SGTC_1909|Compound:st060837|FD-Score:-3.59|P-value:2.93E-4 ID:SGTC_1915|Compound:st067105|FD-Score:34.20|P-value:3.14E-253 ID:SGTC_1930|Compound:st074634|FD-Score:13.60|P-value:2.62E-42 ID:SGTC_2004|Compound:4023728|FD-Score:8.78|P-value:6.44E-19 ID:SGTC_2016|Compound:5121758|FD-Score:3.82|P-value:4.86E-5 ID:SGTC_2018|Compound:5133068|FD-Score:4.94|P-value:2.84E-7 ID:SGTC_2019|Compound:4016004|FD-Score:6.33|P-value:9.18E-11 ID:SGTC_2026|Compound:5148700|FD-Score:3.43|P-value:2.21E-4 ID:SGTC_2035|Compound:5154463|FD-Score:5.98|P-value:8.07E-10 ID:SGTC_2067|Compound:5224629|FD-Score:5.91|P-value:1.24E-9 ID:SGTC_2073|Compound:5212005|FD-Score:3.41|P-value:2.40E-4 ID:SGTC_2090|Compound:5301565|FD-Score:3.41|P-value:2.41E-4 ID:SGTC_2093|Compound:5331342|FD-Score:3.89|P-value:3.73E-5 ID:SGTC_2110|Compound:5483698|FD-Score:7.81|P-value:2.15E-15 ID:SGTC_2112|Compound:5488546|FD-Score:3.15|P-value:6.12E-4 ID:SGTC_2113|Compound:5491891|FD-Score:6.08|P-value:4.42E-10 ID:SGTC_2151|Compound:5563267|FD-Score:12.90|P-value:2.87E-38 ID:SGTC_2172|Compound:5754775|FD-Score:4.29|P-value:6.47E-6 ID:SGTC_2225|Compound:6654152|FD-Score:5.05|P-value:1.56E-7 ID:SGTC_2226|Compound:7298446|FD-Score:3.40|P-value:2.55E-4 ID:SGTC_2233|Compound:sulbentine|FD-Score:26.70|P-value:4.42E-156 ID:SGTC_2246|Compound:7293507|FD-Score:8.68|P-value:1.52E-18 ID:SGTC_2299|Compound:7976368|FD-Score:3.99|P-value:2.37E-5 ID:SGTC_2306|Compound:7482397|FD-Score:13.80|P-value:3.55E-43 ID:SGTC_2311|Compound:7694451|FD-Score:3.91|P-value:3.34E-5 ID:SGTC_2323|Compound:6148992|FD-Score:15.60|P-value:1.48E-54 ID:SGTC_2328|Compound:6201408|FD-Score:4.53|P-value:2.11E-6 ID:SGTC_2339|Compound:9000433|FD-Score:3.04|P-value:9.09E-4 ID:SGTC_2378|Compound:9074213|FD-Score:3.33|P-value:3.23E-4 ID:SGTC_2396|Compound:5342950|FD-Score:3.08|P-value:7.72E-4 ID:SGTC_2408|Compound:sulbentine|FD-Score:7.66|P-value:6.99E-15 ID:SGTC_2411|Compound:st077133|FD-Score:16.60|P-value:1.21E-61 ID:SGTC_2430|Compound:5571206|FD-Score:10.60|P-value:1.40E-26 ID:SGTC_2451|Compound:5856223|FD-Score:7.71|P-value:4.71E-15 ID:SGTC_2466|Compound:5983409|FD-Score:3.05|P-value:8.76E-4 ID:SGTC_2470|Compound:5664817|FD-Score:3.37|P-value:2.80E-4 ID:SGTC_2493|Compound:resveratrol|FD-Score:3.90|P-value:3.59E-5 ID:SGTC_2494|Compound:18-aminoabieta-8,11,13-triene sulfate|FD-Score:4.93|P-value:3.03E-7 ID:SGTC_2495|Compound:cafestol|FD-Score:3.97|P-value:2.64E-5 ID:SGTC_2496|Compound:diffractaic acid|FD-Score:3.44|P-value:2.18E-4 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:16.30|P-value:6.03E-60 ID:SGTC_2522|Compound:biochanin a|FD-Score:12.00|P-value:2.24E-33 ID:SGTC_2526|Compound:patulin|FD-Score:3.64|P-value:1.01E-4 ID:SGTC_2533|Compound:agelasine|FD-Score:3.31|P-value:3.55E-4 ID:SGTC_2544|Compound:sphondin|FD-Score:22.00|P-value:7.29E-107 ID:SGTC_2565|Compound:isoliquiritigenin|FD-Score:3.21|P-value:4.98E-4 ID:SGTC_2566|Compound:crystal violet carbinol|FD-Score:-3.62|P-value:2.61E-4 ID:SGTC_2579|Compound:2',5'-dihydroxy-4-methoxychalcone|FD-Score:5.12|P-value:1.12E-7 ID:SGTC_2601|Compound:securinine|FD-Score:4.59|P-value:1.60E-6 ID:SGTC_2612|Compound:dictamnine|FD-Score:18.50|P-value:1.03E-75 ID:SGTC_2634|Compound:4'-methoxyflavone|FD-Score:3.22|P-value:4.76E-4 ID:SGTC_2721|Compound:ifenprodil|FD-Score:-3.47|P-value:4.55E-4 ID:SGTC_2738|Compound:aclarubicin|FD-Score:10.90|P-value:6.55E-28 ID:SGTC_2739|Compound:tacrine|FD-Score:-3.33|P-value:7.37E-4 ID:SGTC_2829|Compound:7992743|FD-Score:4.92|P-value:3.18E-7 ID:SGTC_2836|Compound:9010338|FD-Score:-4.38|P-value:1.23E-5 ID:SGTC_2837|Compound:9008476|FD-Score:3.89|P-value:3.63E-5 ID:SGTC_2921|Compound:7974240|FD-Score:15.50|P-value:2.12E-54 ID:SGTC_2947|Compound:9072639|FD-Score:6.85|P-value:2.64E-12 ID:SGTC_2949|Compound:9072542|FD-Score:4.44|P-value:3.33E-6 ID:SGTC_2952|Compound:9073731|FD-Score:7.66|P-value:7.26E-15 ID:SGTC_2989|Compound:9073649|FD-Score:3.75|P-value:6.59E-5 ID:SGTC_2993|Compound:9054257|FD-Score:-4.39|P-value:1.19E-5 ID:SGTC_3001|Compound:9076041|FD-Score:4.15|P-value:1.23E-5 ID:SGTC_3075|Compound:9116269|FD-Score:-3.43|P-value:5.09E-4 ID:SGTC_3139|Compound:9095020|FD-Score:3.63|P-value:1.04E-4 ID:SGTC_3141|Compound:9094609|FD-Score:-4.84|P-value:1.45E-6 ID:SGTC_3144|Compound:9087057|FD-Score:3.30|P-value:3.59E-4 ID:SGTC_3212|Compound:9128307|FD-Score:3.52|P-value:1.58E-4 ID:SGTC_3215|Compound:9129942|FD-Score:3.32|P-value:3.41E-4 ID:SGTC_3217|Compound:9129673|FD-Score:-3.26|P-value:9.42E-4 ID:SGTC_3223|Compound:9129970|FD-Score:4.64|P-value:1.24E-6 ID:SGTC_3236|Compound:9132701|FD-Score:4.35|P-value:5.02E-6 ID:SGTC_3247|Compound:9135149|FD-Score:5.26|P-value:5.26E-8 ID:SGTC_3264|Compound:9137442|FD-Score:6.53|P-value:2.32E-11 ID:SGTC_3271|Compound:9137798|FD-Score:6.78|P-value:4.37E-12 ID:SGTC_3282|Compound:9108498|FD-Score:9.83|P-value:3.74E-23 ID:SGTC_3317|Compound:9138495|FD-Score:12.10|P-value:3.89E-34 ID:SGTC_3355|Compound:9151058|FD-Score:3.45|P-value:2.06E-4

Top fitness defect scores for YOR207C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_1915 st067105 34.20 30.6 µM 3.14E-253 RNA pol III & RNase P/MRP 1 1.04E-256 10.40
2 SGTC_210 3551-0445 33.00 56.8 µM 2.70E-235 1 1.82E-238 18.70
3 SGTC_1643 st009866 28.10 20.2 µM 9.71E-172 1 7.72E-174 12.60
4 SGTC_2233 sulbentine 26.70 40.4 µM 4.42E-156 1 6.36E-158 6.19
5 SGTC_177 1327-0068 24.40 8.4 µM 2.47E-130 1 9.22E-132 8.14
6 SGTC_2544 sphondin 22.00 68.5 µM 7.29E-107 RNA pol III & RNase P/MRP 2 6.35E-108 7.21
7 SGTC_829 1635-0120 19.60 117.0 µM 8.77E-85 DNA damage response 2 1.65E-85 4.34
8 SGTC_2612 dictamnine 18.50 15.5 µM 1.03E-75 RNA pol III & RNase P/MRP 3 2.61E-76 2.98
9 SGTC_2411 st077133 16.60 39.9 µM 1.21E-61 RNA pol III & RNase P/MRP 5 4.85E-62 3.11
10 SGTC_2510 benzyl isothiocyanate 16.30 8.3 µM 6.03E-60 1 2.54E-60 4.51
11 SGTC_2323 6148992 15.60 148.3 µM 1.48E-54 2 7.38E-55 8.35
12 SGTC_2921 7974240 15.50 10.7 µM 2.12E-54 2 1.06E-54 7.20
13 SGTC_611 3453-1652 15.00 23.7 µM 3.69E-51 1 2.04E-51 4.50
14 SGTC_503 tyrphostin 8 15.00 294.0 µM 1.20E-50 TSC3-RPN4 1 6.73E-51 6.38
15 SGTC_2306 7482397 13.80 179.5 µM 3.55E-43 RPP1 & pyrimidine depletion 1 2.47E-43 2.32
16 SGTC_1930 st074634 13.60 34.3 µM 2.62E-42 RNA pol III & RNase P/MRP 2 1.87E-42 0.19
17 SGTC_2151 5563267 12.90 85.4 µM 2.87E-38 2 2.28E-38 3.20
18 SGTC_1525 8-methoxypsoralen 12.80 92.5 µM 1.09E-37 DNA damage response 2 8.79E-38 4.85
19 SGTC_3317 9138495 12.10 8.8 µM 3.89E-34 1 3.45E-34 2.34
20 SGTC_2522 biochanin a 12.00 4.9 µM 2.24E-33 RNA pol III & RNase P/MRP 2 2.03E-33 4.19

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.432 1.20E-152 YOR116C RPO31 het RNA polymerase III largest subunit C160, part of core enzyme; similar to bacterial beta-prime subunit and to RPA190 and RPO21
0.424 2.34E-146 YLR243W GPN3 het Putative GTPase with a role in biogenesis of RNA pol II and polIII; may be involved in assembly of RNA polymerases II and III and in their transport into the nucleus; contains a Gly-Pro-Asn motif in the G domain; similar to Npa3p and Gpn2p
0.356 1.13E-100 YDR527W RBA50 het Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1
0.355 2.78E-100 YDL150W RPC53 het RNA polymerase III subunit C53
0.343 2.68E-93 YDL152W_d YDL152W_d het Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SAS10/YDL153C, a component of the small ribosomal subunit processosome
0.330 1.03E-85 YAL024C LTE1 hom Protein similar to GDP/GTP exchange factors but without detectable GEF activity; required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures
0.306 1.77E-73 YMR185W RTP1 het Protein required for the nuclear import and biogenesis of RNA pol II; conflicting evidence on whether null mutant is viable with elongated buds, or inviable; interacts with Rpb2, Rpb3, Nup116p, Nup100p and components of the R2TP complex (Rvb1p, Rvb2p, Pih1p); similar to human TMCO7 gene
0.287 1.97E-64 YNL298W CLA4 hom Cdc42p-activated signal transducing kinase of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p
0.283 6.00E-63 YOR349W CIN1 hom Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
0.276 1.40E-59 YML124C TUB3 hom Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication
0.271 1.95E-57 YPL241C CIN2 hom GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2
0.259 1.53E-52 YNL221C POP1 het Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P
0.244 1.57E-46 YDR225W HTA1 hom Histone H2A, core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
0.242 7.95E-46 YGR083C GCD2 het Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
0.241 2.14E-45 YOR260W GCD1 het Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression