YOR293W / RPS10A

Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S10, no bacterial homolog; RPS10A has a paralog, RPS10B, that arose from the whole genome duplication

Zygosity: Homozygous strain
fixedexpanded
Profile for YOR293W / RPS10A

Click on Significant Values for Screen Details ID:SGTC_58|Compound:0957-0393|FD-Score:-3.58|P-value:4.43E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:3.40|P-value:2.97E-4 ID:SGTC_146|Compound:3448-8650|FD-Score:6.40|P-value:1.20E-10 ID:SGTC_206|Compound:4546-0025|FD-Score:3.92|P-value:4.11E-5 ID:SGTC_221|Compound:trifluoperazine|FD-Score:10.10|P-value:2.32E-23 ID:SGTC_232|Compound:clozapine|FD-Score:6.86|P-value:5.80E-12 ID:SGTC_299|Compound:1273-0059|FD-Score:-3.72|P-value:2.77E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:11.20|P-value:2.00E-28 ID:SGTC_304|Compound:1310-0298|FD-Score:-4.54|P-value:1.07E-5 ID:SGTC_309|Compound:k408-0051|FD-Score:5.54|P-value:1.86E-8 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.67|P-value:4.59E-8 ID:SGTC_313|Compound:3474-0040|FD-Score:4.94|P-value:4.20E-7 ID:SGTC_343|Compound:4130-2827|FD-Score:4.70|P-value:1.34E-6 ID:SGTC_345|Compound:1362-0200|FD-Score:-3.60|P-value:4.24E-4 ID:SGTC_422|Compound:cantharidin|FD-Score:5.61|P-value:1.24E-8 ID:SGTC_431|Compound:k089-0097|FD-Score:-3.69|P-value:3.04E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:3.39|P-value:3.07E-4 ID:SGTC_447|Compound:ml7|FD-Score:3.46|P-value:2.43E-4 ID:SGTC_449|Compound:xestospongin c|FD-Score:5.35|P-value:5.16E-8 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.30|P-value:3.03E-7 ID:SGTC_513|Compound:4245-1575|FD-Score:-3.41|P-value:8.07E-4 ID:SGTC_535|Compound:2293-4129|FD-Score:3.60|P-value:1.44E-4 ID:SGTC_692|Compound:k241-0027|FD-Score:3.30|P-value:4.26E-4 ID:SGTC_711|Compound:k292-0785|FD-Score:5.65|P-value:1.04E-8 ID:SGTC_754|Compound:3474-0146|FD-Score:4.73|P-value:1.17E-6 ID:SGTC_773|Compound:4358-1457|FD-Score:-3.62|P-value:3.95E-4 ID:SGTC_782|Compound:0083-0095|FD-Score:3.86|P-value:5.36E-5 ID:SGTC_800|Compound:3448-7362|FD-Score:8.19|P-value:3.66E-16 ID:SGTC_809|Compound:3998-0021|FD-Score:-4.11|P-value:6.29E-5 ID:SGTC_830|Compound:4076-0286|FD-Score:3.84|P-value:5.71E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:3.63|P-value:1.31E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:-3.67|P-value:3.23E-4 ID:SGTC_888|Compound:0916-0002|FD-Score:7.81|P-value:6.74E-15 ID:SGTC_900|Compound:1112-0045|FD-Score:6.38|P-value:1.37E-10 ID:SGTC_940|Compound:3232-1287|FD-Score:7.98|P-value:1.92E-15 ID:SGTC_970|Compound:1315-0089|FD-Score:-4.83|P-value:2.92E-6 ID:SGTC_983|Compound:1491-0821|FD-Score:-3.93|P-value:1.27E-4 ID:SGTC_985|Compound:1493-0307|FD-Score:-3.76|P-value:2.39E-4 ID:SGTC_1113|Compound:artemisinin|FD-Score:-3.38|P-value:8.93E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.92|P-value:2.17E-9 ID:SGTC_1203|Compound:3992-3522|FD-Score:-4.23|P-value:3.94E-5 ID:SGTC_1351|Compound:1496-0003|FD-Score:3.61|P-value:1.41E-4 ID:SGTC_1395|Compound:3486-0190|FD-Score:-3.36|P-value:9.26E-4 ID:SGTC_1403|Compound:3909-7815|FD-Score:3.05|P-value:9.81E-4 ID:SGTC_1612|Compound:st002233|FD-Score:4.66|P-value:1.63E-6 ID:SGTC_1665|Compound:st014639|FD-Score:3.25|P-value:5.14E-4 ID:SGTC_1712|Compound:st032288|FD-Score:4.54|P-value:2.91E-6 ID:SGTC_1743|Compound:st037606|FD-Score:3.17|P-value:6.54E-4 ID:SGTC_1754|Compound:st042065|FD-Score:3.59|P-value:1.49E-4 ID:SGTC_1760|Compound:st045453|FD-Score:4.10|P-value:2.01E-5 ID:SGTC_1781|Compound:st038725|FD-Score:9.39|P-value:1.35E-20 ID:SGTC_1797|Compound:st048695|FD-Score:5.16|P-value:1.40E-7 ID:SGTC_1991|Compound:st073000|FD-Score:7.20|P-value:5.79E-13 ID:SGTC_2002|Compound:4023503|FD-Score:-3.49|P-value:6.17E-4 ID:SGTC_2012|Compound:4023501|FD-Score:-3.98|P-value:1.03E-4 ID:SGTC_2023|Compound:5144124|FD-Score:3.22|P-value:5.56E-4 ID:SGTC_2028|Compound:5153890|FD-Score:6.10|P-value:7.52E-10 ID:SGTC_2128|Compound:5255449|FD-Score:-4.18|P-value:4.72E-5 ID:SGTC_2132|Compound:5317594|FD-Score:-3.34|P-value:9.88E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:7.30|P-value:2.90E-13 ID:SGTC_2276|Compound:7947513|FD-Score:-3.79|P-value:2.12E-4 ID:SGTC_2285|Compound:7945142|FD-Score:-3.62|P-value:3.84E-4 ID:SGTC_2308|Compound:7584454|FD-Score:-3.65|P-value:3.45E-4 ID:SGTC_2456|Compound:5770359|FD-Score:-4.21|P-value:4.21E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:-4.20|P-value:4.46E-5 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:7.96|P-value:2.13E-15 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.64|P-value:2.47E-14 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:12.90|P-value:7.60E-37 ID:SGTC_2699|Compound:st077704|FD-Score:3.93|P-value:3.93E-5 ID:SGTC_2749|Compound:bexarotene|FD-Score:3.57|P-value:1.63E-4 ID:SGTC_2752|Compound:diclazuril|FD-Score:-6.27|P-value:1.56E-9 ID:SGTC_2756|Compound:carbadox|FD-Score:-3.57|P-value:4.64E-4 ID:SGTC_2773|Compound:thioridazine|FD-Score:6.96|P-value:3.11E-12 ID:SGTC_2774|Compound:tamoxifen|FD-Score:5.36|P-value:5.00E-8 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:8.74|P-value:4.00E-18 ID:SGTC_2779|Compound:methotrexate|FD-Score:6.10|P-value:7.40E-10 ID:SGTC_2790|Compound:5423970|FD-Score:3.45|P-value:2.46E-4 ID:SGTC_2869|Compound:9037858|FD-Score:3.13|P-value:7.59E-4 ID:SGTC_2896|Compound:9052656|FD-Score:-5.62|P-value:5.77E-8 ID:SGTC_2974|Compound:9094440|FD-Score:3.48|P-value:2.23E-4 ID:SGTC_3012|Compound:9080433|FD-Score:-3.56|P-value:4.87E-4 ID:SGTC_3037|Compound:9091026|FD-Score:3.44|P-value:2.58E-4 ID:SGTC_3152|Compound:9099253|FD-Score:8.13|P-value:5.65E-16 ID:SGTC_3218|Compound:9131285|FD-Score:4.17|P-value:1.44E-5 ID:SGTC_3219|Compound:9131112|FD-Score:-3.82|P-value:1.87E-4 ID:SGTC_3303|Compound:9125618|FD-Score:-7.17|P-value:5.31E-12 ID:SGTC_3309|Compound:9129340|FD-Score:3.34|P-value:3.73E-4 ID:SGTC_3320|Compound:9137005|FD-Score:3.26|P-value:4.86E-4 ID:SGTC_3329|Compound:9141233|FD-Score:-3.42|P-value:7.81E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:-3.58|P-value:4.43E-4 ID:SGTC_118|Compound:0083-0097|FD-Score:3.40|P-value:2.97E-4 ID:SGTC_146|Compound:3448-8650|FD-Score:6.40|P-value:1.20E-10 ID:SGTC_206|Compound:4546-0025|FD-Score:3.92|P-value:4.11E-5 ID:SGTC_221|Compound:trifluoperazine|FD-Score:10.10|P-value:2.32E-23 ID:SGTC_232|Compound:clozapine|FD-Score:6.86|P-value:5.80E-12 ID:SGTC_299|Compound:1273-0059|FD-Score:-3.72|P-value:2.77E-4 ID:SGTC_301|Compound:4119-0100|FD-Score:11.20|P-value:2.00E-28 ID:SGTC_304|Compound:1310-0298|FD-Score:-4.54|P-value:1.07E-5 ID:SGTC_309|Compound:k408-0051|FD-Score:5.54|P-value:1.86E-8 ID:SGTC_310|Compound:1273-0058|FD-Score:-5.67|P-value:4.59E-8 ID:SGTC_313|Compound:3474-0040|FD-Score:4.94|P-value:4.20E-7 ID:SGTC_343|Compound:4130-2827|FD-Score:4.70|P-value:1.34E-6 ID:SGTC_345|Compound:1362-0200|FD-Score:-3.60|P-value:4.24E-4 ID:SGTC_422|Compound:cantharidin|FD-Score:5.61|P-value:1.24E-8 ID:SGTC_431|Compound:k089-0097|FD-Score:-3.69|P-value:3.04E-4 ID:SGTC_445|Compound:e6 berbamine|FD-Score:3.39|P-value:3.07E-4 ID:SGTC_447|Compound:ml7|FD-Score:3.46|P-value:2.43E-4 ID:SGTC_449|Compound:xestospongin c|FD-Score:5.35|P-value:5.16E-8 ID:SGTC_453|Compound:enantio-paf c16|FD-Score:-5.30|P-value:3.03E-7 ID:SGTC_513|Compound:4245-1575|FD-Score:-3.41|P-value:8.07E-4 ID:SGTC_535|Compound:2293-4129|FD-Score:3.60|P-value:1.44E-4 ID:SGTC_692|Compound:k241-0027|FD-Score:3.30|P-value:4.26E-4 ID:SGTC_711|Compound:k292-0785|FD-Score:5.65|P-value:1.04E-8 ID:SGTC_754|Compound:3474-0146|FD-Score:4.73|P-value:1.17E-6 ID:SGTC_773|Compound:4358-1457|FD-Score:-3.62|P-value:3.95E-4 ID:SGTC_782|Compound:0083-0095|FD-Score:3.86|P-value:5.36E-5 ID:SGTC_800|Compound:3448-7362|FD-Score:8.19|P-value:3.66E-16 ID:SGTC_809|Compound:3998-0021|FD-Score:-4.11|P-value:6.29E-5 ID:SGTC_830|Compound:4076-0286|FD-Score:3.84|P-value:5.71E-5 ID:SGTC_832|Compound:4083-0019|FD-Score:3.63|P-value:1.31E-4 ID:SGTC_878|Compound:0828-0289|FD-Score:-3.67|P-value:3.23E-4 ID:SGTC_888|Compound:0916-0002|FD-Score:7.81|P-value:6.74E-15 ID:SGTC_900|Compound:1112-0045|FD-Score:6.38|P-value:1.37E-10 ID:SGTC_940|Compound:3232-1287|FD-Score:7.98|P-value:1.92E-15 ID:SGTC_970|Compound:1315-0089|FD-Score:-4.83|P-value:2.92E-6 ID:SGTC_983|Compound:1491-0821|FD-Score:-3.93|P-value:1.27E-4 ID:SGTC_985|Compound:1493-0307|FD-Score:-3.76|P-value:2.39E-4 ID:SGTC_1113|Compound:artemisinin|FD-Score:-3.38|P-value:8.93E-4 ID:SGTC_1130|Compound:3454-2858|FD-Score:5.92|P-value:2.17E-9 ID:SGTC_1203|Compound:3992-3522|FD-Score:-4.23|P-value:3.94E-5 ID:SGTC_1351|Compound:1496-0003|FD-Score:3.61|P-value:1.41E-4 ID:SGTC_1395|Compound:3486-0190|FD-Score:-3.36|P-value:9.26E-4 ID:SGTC_1403|Compound:3909-7815|FD-Score:3.05|P-value:9.81E-4 ID:SGTC_1612|Compound:st002233|FD-Score:4.66|P-value:1.63E-6 ID:SGTC_1665|Compound:st014639|FD-Score:3.25|P-value:5.14E-4 ID:SGTC_1712|Compound:st032288|FD-Score:4.54|P-value:2.91E-6 ID:SGTC_1743|Compound:st037606|FD-Score:3.17|P-value:6.54E-4 ID:SGTC_1754|Compound:st042065|FD-Score:3.59|P-value:1.49E-4 ID:SGTC_1760|Compound:st045453|FD-Score:4.10|P-value:2.01E-5 ID:SGTC_1781|Compound:st038725|FD-Score:9.39|P-value:1.35E-20 ID:SGTC_1797|Compound:st048695|FD-Score:5.16|P-value:1.40E-7 ID:SGTC_1991|Compound:st073000|FD-Score:7.20|P-value:5.79E-13 ID:SGTC_2002|Compound:4023503|FD-Score:-3.49|P-value:6.17E-4 ID:SGTC_2012|Compound:4023501|FD-Score:-3.98|P-value:1.03E-4 ID:SGTC_2023|Compound:5144124|FD-Score:3.22|P-value:5.56E-4 ID:SGTC_2028|Compound:5153890|FD-Score:6.10|P-value:7.52E-10 ID:SGTC_2128|Compound:5255449|FD-Score:-4.18|P-value:4.72E-5 ID:SGTC_2132|Compound:5317594|FD-Score:-3.34|P-value:9.88E-4 ID:SGTC_2250|Compound:alverine citrate|FD-Score:7.30|P-value:2.90E-13 ID:SGTC_2276|Compound:7947513|FD-Score:-3.79|P-value:2.12E-4 ID:SGTC_2285|Compound:7945142|FD-Score:-3.62|P-value:3.84E-4 ID:SGTC_2308|Compound:7584454|FD-Score:-3.65|P-value:3.45E-4 ID:SGTC_2456|Compound:5770359|FD-Score:-4.21|P-value:4.21E-5 ID:SGTC_2582|Compound:agaric acid|FD-Score:-4.20|P-value:4.46E-5 ID:SGTC_2658|Compound:polymyxin b sulfate|FD-Score:7.96|P-value:2.13E-15 ID:SGTC_2688|Compound:kanamycin b|FD-Score:7.64|P-value:2.47E-14 ID:SGTC_2697|Compound:mebhydrolin|FD-Score:12.90|P-value:7.60E-37 ID:SGTC_2699|Compound:st077704|FD-Score:3.93|P-value:3.93E-5 ID:SGTC_2749|Compound:bexarotene|FD-Score:3.57|P-value:1.63E-4 ID:SGTC_2752|Compound:diclazuril|FD-Score:-6.27|P-value:1.56E-9 ID:SGTC_2756|Compound:carbadox|FD-Score:-3.57|P-value:4.64E-4 ID:SGTC_2773|Compound:thioridazine|FD-Score:6.96|P-value:3.11E-12 ID:SGTC_2774|Compound:tamoxifen|FD-Score:5.36|P-value:5.00E-8 ID:SGTC_2775|Compound:cyproheptadine|FD-Score:8.74|P-value:4.00E-18 ID:SGTC_2779|Compound:methotrexate|FD-Score:6.10|P-value:7.40E-10 ID:SGTC_2790|Compound:5423970|FD-Score:3.45|P-value:2.46E-4 ID:SGTC_2869|Compound:9037858|FD-Score:3.13|P-value:7.59E-4 ID:SGTC_2896|Compound:9052656|FD-Score:-5.62|P-value:5.77E-8 ID:SGTC_2974|Compound:9094440|FD-Score:3.48|P-value:2.23E-4 ID:SGTC_3012|Compound:9080433|FD-Score:-3.56|P-value:4.87E-4 ID:SGTC_3037|Compound:9091026|FD-Score:3.44|P-value:2.58E-4 ID:SGTC_3152|Compound:9099253|FD-Score:8.13|P-value:5.65E-16 ID:SGTC_3218|Compound:9131285|FD-Score:4.17|P-value:1.44E-5 ID:SGTC_3219|Compound:9131112|FD-Score:-3.82|P-value:1.87E-4 ID:SGTC_3303|Compound:9125618|FD-Score:-7.17|P-value:5.31E-12 ID:SGTC_3309|Compound:9129340|FD-Score:3.34|P-value:3.73E-4 ID:SGTC_3320|Compound:9137005|FD-Score:3.26|P-value:4.86E-4 ID:SGTC_3329|Compound:9141233|FD-Score:-3.42|P-value:7.81E-4

Top fitness defect scores for YOR293W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_2697 mebhydrolin 12.90 72.4 µM 7.60E-37 NEO1 10 2.22E-38
2 SGTC_301 4119-0100 11.20 24.5 µM 2.00E-28 NEO1 14 1.70E-29
3 SGTC_221 trifluoperazine 10.10 10.3 µM 2.32E-23 NEO1-PIK1 57 3.65E-24
4 SGTC_1781 st038725 9.39 66.3 µM 1.35E-20 NEO1 20 2.96E-21
5 SGTC_2775 cyproheptadine 8.74 69.6 µM 4.00E-18 1 1.17E-18
6 SGTC_800 3448-7362 8.19 155.0 µM 3.66E-16 translation 14 1.33E-16
7 SGTC_3152 9099253 8.13 49.5 µM 5.65E-16 NEO1-PIK1 34 2.10E-16
8 SGTC_940 3232-1287 7.98 54.8 µM 1.92E-15 NEO1 4 7.59E-16
9 SGTC_2658 polymyxin b sulfate 7.96 77.0 µM 2.13E-15 NEO1 10 8.45E-16
10 SGTC_888 0916-0002 7.81 7.0 µM 6.74E-15 NEO1 15 2.82E-15
11 SGTC_2688 kanamycin b 7.64 96.7 µM 2.47E-14 calcium & mitochondrial duress 82 1.10E-14
12 SGTC_2250 alverine citrate 7.30 130.0 µM 2.90E-13 31 1.45E-13
13 SGTC_1991 st073000 7.20 8.9 µM 5.79E-13 NEO1 21 2.99E-13
14 SGTC_2773 thioridazine 6.96 9.1 µM 3.11E-12 1 1.73E-12
15 SGTC_232 clozapine 6.86 119.0 µM 5.80E-12 NEO1 25 3.33E-12
16 SGTC_146 3448-8650 6.40 53.1 µM 1.20E-10 NEO1-PIK1 47 7.91E-11
17 SGTC_900 1112-0045 6.38 141.0 µM 1.37E-10 NEO1 9 9.04E-11
18 SGTC_2779 methotrexate 6.10 400.0 µM 7.40E-10 11 5.25E-10
19 SGTC_2028 5153890 6.10 36.4 µM 7.52E-10 cell wall signaling 11 5.34E-10
20 SGTC_1130 3454-2858 5.92 15.9 µM 2.17E-9 NEO1 43 1.61E-9

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.532 1.39E-244 YIL048W NEO1 het Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus
0.508 4.12E-219 YJL053W PEP8 hom Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress
0.470 1.15E-183 YHR012W VPS29 hom Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval
0.463 1.15E-177 YDR372C VPS74 hom Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33
0.457 6.47E-172 YOR039W CKB2 hom Beta' regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerase
0.455 5.05E-171 YJL154C VPS35 hom Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p
0.432 1.20E-152 YDR455C_d YDR455C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YDR456W
0.401 2.57E-129 YGL019W CKB1 hom Beta regulatory subunit of casein kinase 2 (CK2), a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases
0.400 5.28E-129 YDR456W NHX1 hom Na+/H+ and K+/H+ exchanger, required for intracellular sequestration of Na+ and K+; located in the vacuole and late endosome compartments; required for osmotolerance to acute hypertonic shock and for vacuolar fusion
0.380 3.22E-115 YAL009W SPO7 hom Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation
0.372 1.24E-110 YCR064C_d YCR064C_d hom Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified gene BUD31
0.361 1.66E-103 YHR004C NEM1 hom Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard
0.335 1.92E-88 YJL124C LSM1 hom Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; forms cytoplasmic foci upon DNA replication stress
0.326 5.11E-84 YML094C-A_d YML094C-A_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene GIM5/YML094W; deletion confers sensitivity to GSAO
0.322 2.15E-81 YDL090C RAM1 hom Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit