| Correlation | pval | ORF | Gene | Zygosity | Description |
|---|
| 0.120 |
2.62E-12 |
YKL052C |
ASK1 |
het |
Essential subunit of the Dam1 complex (aka DASH complex); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases; protein abundance increases in response to DNA replication stress |
| 0.114 |
3.91E-11 |
YKL051W |
SFK1 |
hom |
Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane |
| 0.106 |
6.59E-10 |
YBR257W |
POP4 |
het |
Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; binds to the RPR1 RNA subunit in RNase P |
| 0.105 |
1.13E-9 |
YNL090W |
RHO2 |
hom |
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly |
| 0.099 |
9.99E-9 |
YDR357C_p |
CNL1_p |
hom |
Protein of unknown function; likely member of BLOC complex involved in endosomal cargo sorting; null mutant is sensitive to drug inducing secretion of vacuolar cargo; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm |
| 0.094 |
5.27E-8 |
YNL268W |
LYP1 |
hom |
Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids |
| 0.093 |
7.75E-8 |
YMR093W |
UTP15 |
het |
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA |
| 0.091 |
1.49E-7 |
YDR398W |
UTP5 |
het |
Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit |
| 0.086 |
5.97E-7 |
YER142C |
MAG1 |
hom |
3-methyl-adenine DNA glycosylase; involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired; protein abundance increases in response to DNA replication stress |
| 0.082 |
2.00E-6 |
YOR312C |
RPL20B |
hom |
Ribosomal 60S subunit protein L20B; homologous to mammalian ribosomal protein L18A, no bacterial homolog; RPL20B has a paralog, RPL20A, that arose from the whole genome duplication |
| 0.081 |
2.35E-6 |
YGR148C |
RPL24B |
hom |
Ribosomal 60S subunit protein L24B; not essential for translation but may be required for normal translation rate; homologous to mammalian ribosomal protein L24, no bacterial homolog; RPL24B has a paralog, RPL24A, that arose from the whole genome duplication |
| 0.081 |
2.85E-6 |
YPL028W |
ERG10 |
het |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis |
| 0.079 |
4.35E-6 |
YOR143C |
THI80 |
het |
Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate) |
| 0.079 |
4.79E-6 |
YLR266C |
PDR8 |
hom |
Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon; PDR8 has a paralog, YRR1, that arose from the whole genome duplication |
| 0.078 |
6.16E-6 |
YLR018C |
POM34 |
hom |
Subunit of the transmembrane ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport, NPC biogenesis and spindle pole body duplication |
