YPR107C / YTH1

Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation

Zygosity: Heterozygous strain
fixedexpanded
Profile for YPR107C / YTH1

Click on Significant Values for Screen Details ID:SGTC_9|Compound:0092-0002|FD-Score:4.78|P-value:3.83E-4 ID:SGTC_16|Compound:erodoxin|FD-Score:6.00|P-value:1.23E-5 ID:SGTC_22|Compound:0964-0034|FD-Score:6.47|P-value:2.80E-6 ID:SGTC_29|Compound:0299-0004|FD-Score:5.86|P-value:1.91E-5 ID:SGTC_35|Compound:0133-0054|FD-Score:-5.22|P-value:1.48E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:8.33|P-value:2.61E-9 ID:SGTC_40|Compound:0327-0103|FD-Score:-5.09|P-value:2.11E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:7.74|P-value:2.80E-8 ID:SGTC_64|Compound:000l-0018|FD-Score:16.20|P-value:5.84E-30 ID:SGTC_70|Compound:0141-0289|FD-Score:-4.93|P-value:3.19E-4 ID:SGTC_86|Compound:0417-1630|FD-Score:15.40|P-value:2.68E-27 ID:SGTC_103|Compound:0844-0104|FD-Score:8.40|P-value:1.93E-9 ID:SGTC_107|Compound:0358-0022|FD-Score:14.20|P-value:1.89E-23 ID:SGTC_117|Compound:lucigenin|FD-Score:5.73|P-value:2.86E-5 ID:SGTC_129|Compound:0088-0017|FD-Score:-4.61|P-value:6.99E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:25.80|P-value:6.99E-73 ID:SGTC_138|Compound:0850-0259|FD-Score:18.50|P-value:1.72E-38 ID:SGTC_142|Compound:0335-0849|FD-Score:33.70|P-value:2.36E-123 ID:SGTC_157|Compound:1348-1695|FD-Score:9.19|P-value:5.85E-11 ID:SGTC_158|Compound:k038-0087|FD-Score:16.70|P-value:5.66E-32 ID:SGTC_159|Compound:3970-0959|FD-Score:6.82|P-value:8.54E-7 ID:SGTC_163|Compound:1327-0036|FD-Score:22.20|P-value:7.88E-55 ID:SGTC_165|Compound:k038-0023|FD-Score:7.21|P-value:2.08E-7 ID:SGTC_168|Compound:3970-0862|FD-Score:8.50|P-value:1.26E-9 ID:SGTC_200|Compound:k038-0079|FD-Score:15.60|P-value:4.88E-28 ID:SGTC_207|Compound:4185-0010|FD-Score:-4.87|P-value:3.66E-4 ID:SGTC_208|Compound:k072-0098|FD-Score:9.16|P-value:6.83E-11 ID:SGTC_214|Compound:4373-3496|FD-Score:4.74|P-value:4.28E-4 ID:SGTC_216|Compound:k038-0035|FD-Score:19.80|P-value:6.51E-44 ID:SGTC_236|Compound:1509-0011|FD-Score:7.65|P-value:3.95E-8 ID:SGTC_248|Compound:streptozotocin|FD-Score:6.23|P-value:5.99E-6 ID:SGTC_268|Compound:camptothecin|FD-Score:19.90|P-value:1.52E-44 ID:SGTC_294|Compound:k038-0071|FD-Score:10.70|P-value:3.00E-14 ID:SGTC_332|Compound:4112-0506|FD-Score:12.10|P-value:1.41E-17 ID:SGTC_340|Compound:k038-0059|FD-Score:8.39|P-value:2.02E-9 ID:SGTC_351|Compound:caspofungin|FD-Score:6.22|P-value:6.22E-6 ID:SGTC_352|Compound:k048-0007|FD-Score:5.32|P-value:9.25E-5 ID:SGTC_354|Compound:2783-3500|FD-Score:5.12|P-value:1.59E-4 ID:SGTC_388|Compound:3',4'-dichloroisocoumarin|FD-Score:4.50|P-value:7.63E-4 ID:SGTC_394|Compound:menadione|FD-Score:4.64|P-value:5.43E-4 ID:SGTC_396|Compound:dithiazanine|FD-Score:7.57|P-value:5.45E-8 ID:SGTC_419|Compound:nsc-638432|FD-Score:-6.54|P-value:2.76E-6 ID:SGTC_431|Compound:k089-0097|FD-Score:-5.28|P-value:1.24E-4 ID:SGTC_451|Compound:chloral hydrate|FD-Score:14.70|P-value:4.59E-25 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-4.75|P-value:4.97E-4 ID:SGTC_467|Compound:ro 31-8220|FD-Score:5.04|P-value:1.95E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:14.00|P-value:4.34E-23 ID:SGTC_533|Compound:1222-0222|FD-Score:4.50|P-value:7.67E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:7.13|P-value:2.75E-7 ID:SGTC_576|Compound:1073-0113|FD-Score:10.50|P-value:9.24E-14 ID:SGTC_580|Compound:1123-0028|FD-Score:17.20|P-value:9.84E-34 ID:SGTC_586|Compound:0957-0265|FD-Score:31.90|P-value:1.57E-110 ID:SGTC_630|Compound:4356-0227|FD-Score:4.85|P-value:3.20E-4 ID:SGTC_635|Compound:k038-0028|FD-Score:8.47|P-value:1.40E-9 ID:SGTC_673|Compound:1082-0474|FD-Score:15.80|P-value:1.34E-28 ID:SGTC_674|Compound:0498-0004|FD-Score:7.94|P-value:1.27E-8 ID:SGTC_707|Compound:0865-0008|FD-Score:5.09|P-value:1.72E-4 ID:SGTC_709|Compound:3807-1509|FD-Score:12.70|P-value:3.65E-19 ID:SGTC_721|Compound:1187-1332|FD-Score:4.80|P-value:3.61E-4 ID:SGTC_743|Compound:1275-0778|FD-Score:7.72|P-value:3.09E-8 ID:SGTC_759|Compound:3486-0358|FD-Score:7.16|P-value:2.50E-7 ID:SGTC_778|Compound:3456-2434|FD-Score:5.05|P-value:1.92E-4 ID:SGTC_788|Compound:1182-0090|FD-Score:5.49|P-value:5.67E-5 ID:SGTC_790|Compound:1575-0012|FD-Score:4.98|P-value:2.33E-4 ID:SGTC_794|Compound:k038-0031|FD-Score:15.00|P-value:6.04E-26 ID:SGTC_801|Compound:0866-0028|FD-Score:4.75|P-value:4.14E-4 ID:SGTC_817|Compound:1391-0715|FD-Score:5.92|P-value:1.62E-5 ID:SGTC_824|Compound:1304-0008|FD-Score:5.50|P-value:5.50E-5 ID:SGTC_829|Compound:1635-0120|FD-Score:15.20|P-value:8.33E-27 ID:SGTC_839|Compound:0122-0028|FD-Score:6.09|P-value:9.35E-6 ID:SGTC_851|Compound:0394-0702|FD-Score:5.82|P-value:2.17E-5 ID:SGTC_852|Compound:0418-0143|FD-Score:7.94|P-value:1.28E-8 ID:SGTC_871|Compound:0574-0004|FD-Score:7.84|P-value:1.88E-8 ID:SGTC_885|Compound:0865-0106|FD-Score:6.07|P-value:1.00E-5 ID:SGTC_943|Compound:3253-1379|FD-Score:-4.62|P-value:6.82E-4 ID:SGTC_984|Compound:1492-0255|FD-Score:8.16|P-value:5.19E-9 ID:SGTC_994|Compound:3910-0338|FD-Score:4.87|P-value:3.02E-4 ID:SGTC_1038|Compound:k292-0204|FD-Score:4.88|P-value:2.97E-4 ID:SGTC_1050|Compound:3232-1156|FD-Score:5.63|P-value:3.83E-5 ID:SGTC_1057|Compound:3448-5381|FD-Score:6.24|P-value:5.85E-6 ID:SGTC_1113|Compound:artemisinin|FD-Score:8.06|P-value:7.89E-9 ID:SGTC_1121|Compound:fusaric acid|FD-Score:6.37|P-value:3.83E-6 ID:SGTC_1133|Compound:3473-0247|FD-Score:5.70|P-value:3.10E-5 ID:SGTC_1161|Compound:k007-0610|FD-Score:14.40|P-value:2.40E-24 ID:SGTC_1188|Compound:1403-0014|FD-Score:7.18|P-value:2.37E-7 ID:SGTC_1197|Compound:1601-0112|FD-Score:4.44|P-value:8.88E-4 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.41|P-value:9.59E-4 ID:SGTC_1239|Compound:0337-0584|FD-Score:15.30|P-value:4.09E-27 ID:SGTC_1255|Compound:0566-0045|FD-Score:12.70|P-value:3.12E-19 ID:SGTC_1266|Compound:0828-0227|FD-Score:5.04|P-value:1.94E-4 ID:SGTC_1271|Compound:0832-2808|FD-Score:4.65|P-value:5.27E-4 ID:SGTC_1294|Compound:1000-1494|FD-Score:12.50|P-value:1.05E-18 ID:SGTC_1330|Compound:1469-0054|FD-Score:5.55|P-value:4.83E-5 ID:SGTC_1371|Compound:2421-0008|FD-Score:7.16|P-value:2.49E-7 ID:SGTC_1374|Compound:2889-5571|FD-Score:12.10|P-value:1.35E-17 ID:SGTC_1397|Compound:3532-0190|FD-Score:5.63|P-value:3.76E-5 ID:SGTC_1493|Compound:4348-0038|FD-Score:9.57|P-value:9.74E-12 ID:SGTC_1635|Compound:st007035|FD-Score:4.60|P-value:6.06E-4 ID:SGTC_1639|Compound:Lupinine o-methylbenzoicacid ester hydrochloride|FD-Score:5.76|P-value:2.60E-5 ID:SGTC_1652|Compound:st011932|FD-Score:11.10|P-value:3.38E-15 ID:SGTC_1696|Compound:st025591|FD-Score:6.16|P-value:7.45E-6 ID:SGTC_1750|Compound:st081859|FD-Score:9.64|P-value:7.02E-12 ID:SGTC_1797|Compound:st048695|FD-Score:5.01|P-value:2.12E-4 ID:SGTC_1851|Compound:st056236|FD-Score:4.97|P-value:2.37E-4 ID:SGTC_1900|Compound:st060200|FD-Score:-5.98|P-value:1.66E-5 ID:SGTC_1901|Compound:st060216|FD-Score:-4.83|P-value:4.09E-4 ID:SGTC_1902|Compound:st060212|FD-Score:-5.64|P-value:4.56E-5 ID:SGTC_1904|Compound:st060225|FD-Score:-4.60|P-value:7.18E-4 ID:SGTC_1905|Compound:st060207|FD-Score:-4.49|P-value:9.31E-4 ID:SGTC_1913|Compound:st060213|FD-Score:5.42|P-value:6.94E-5 ID:SGTC_1915|Compound:st067105|FD-Score:11.70|P-value:1.62E-16 ID:SGTC_1934|Compound:st074720|FD-Score:-4.77|P-value:4.75E-4 ID:SGTC_1968|Compound:st069590|FD-Score:18.00|P-value:1.07E-36 ID:SGTC_2038|Compound:4100038|FD-Score:-5.83|P-value:2.63E-5 ID:SGTC_2041|Compound:5107442|FD-Score:10.80|P-value:2.39E-14 ID:SGTC_2109|Compound:5483026|FD-Score:6.77|P-value:1.00E-6 ID:SGTC_2111|Compound:5486399|FD-Score:17.80|P-value:7.91E-36 ID:SGTC_2124|Compound:5246320|FD-Score:8.00|P-value:9.80E-9 ID:SGTC_2139|Compound:5578692|FD-Score:7.95|P-value:1.20E-8 ID:SGTC_2157|Compound:5649910|FD-Score:6.09|P-value:9.47E-6 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:6.59|P-value:1.85E-6 ID:SGTC_2186|Compound:6124449|FD-Score:6.67|P-value:1.40E-6 ID:SGTC_2225|Compound:6654152|FD-Score:6.91|P-value:6.21E-7 ID:SGTC_2229|Compound:7354935|FD-Score:6.93|P-value:5.64E-7 ID:SGTC_2233|Compound:sulbentine|FD-Score:7.35|P-value:1.24E-7 ID:SGTC_2249|Compound:haloperidol|FD-Score:-6.26|P-value:6.98E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-7.84|P-value:2.52E-8 ID:SGTC_2346|Compound:9031566|FD-Score:5.03|P-value:2.00E-4 ID:SGTC_2374|Compound:9071832|FD-Score:4.86|P-value:3.11E-4 ID:SGTC_2376|Compound:9072922|FD-Score:-4.84|P-value:4.01E-4 ID:SGTC_2380|Compound:9035439|FD-Score:7.27|P-value:1.69E-7 ID:SGTC_2396|Compound:5342950|FD-Score:15.10|P-value:2.51E-26 ID:SGTC_2400|Compound:5203494|FD-Score:7.01|P-value:4.36E-7 ID:SGTC_2408|Compound:sulbentine|FD-Score:6.89|P-value:6.48E-7 ID:SGTC_2410|Compound:aloe-emodin-8-o-glycoside|FD-Score:5.29|P-value:1.01E-4 ID:SGTC_2418|Compound:pentamidine|FD-Score:7.61|P-value:4.71E-8 ID:SGTC_2429|Compound:5902844|FD-Score:25.00|P-value:9.52E-69 ID:SGTC_2446|Compound:5162541|FD-Score:4.50|P-value:7.61E-4 ID:SGTC_2471|Compound:5466956|FD-Score:5.76|P-value:2.58E-5 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:5.43|P-value:6.80E-5 ID:SGTC_2534|Compound:helenine|FD-Score:12.40|P-value:1.64E-18 ID:SGTC_2539|Compound:epi(13)torulosol|FD-Score:-6.42|P-value:4.16E-6 ID:SGTC_2544|Compound:sphondin|FD-Score:6.63|P-value:1.64E-6 ID:SGTC_2575|Compound:plumbagin|FD-Score:7.01|P-value:4.24E-7 ID:SGTC_2582|Compound:agaric acid|FD-Score:7.56|P-value:5.67E-8 ID:SGTC_2586|Compound:curcumin|FD-Score:4.71|P-value:4.57E-4 ID:SGTC_2603|Compound:homopterocarpin|FD-Score:-5.95|P-value:1.82E-5 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:4.91|P-value:2.73E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:19.00|P-value:1.10E-40 ID:SGTC_2662|Compound:daunorubicin|FD-Score:7.23|P-value:1.94E-7 ID:SGTC_2679|Compound:rapamycin|FD-Score:-5.15|P-value:1.79E-4 ID:SGTC_2756|Compound:carbadox|FD-Score:6.36|P-value:3.91E-6 ID:SGTC_2759|Compound:disulfiram|FD-Score:5.00|P-value:2.15E-4 ID:SGTC_2867|Compound:9039098|FD-Score:-5.59|P-value:5.21E-5 ID:SGTC_2890|Compound:9046729|FD-Score:8.09|P-value:6.93E-9 ID:SGTC_2896|Compound:9052656|FD-Score:-4.94|P-value:3.09E-4 ID:SGTC_2912|Compound:7964298|FD-Score:9.63|P-value:7.44E-12 ID:SGTC_2928|Compound:9011484|FD-Score:5.58|P-value:4.38E-5 ID:SGTC_2980|Compound:9014342|FD-Score:4.73|P-value:4.39E-4 ID:SGTC_2997|Compound:9067075|FD-Score:6.91|P-value:6.05E-7 ID:SGTC_3026|Compound:9090633|FD-Score:-5.84|P-value:2.53E-5 ID:SGTC_3030|Compound:9087619|FD-Score:4.74|P-value:4.26E-4 ID:SGTC_3031|Compound:9088762|FD-Score:5.43|P-value:6.82E-5 ID:SGTC_3059|Compound:1327-0034|FD-Score:45.80|P-value:1.14E-224 ID:SGTC_3060|Compound:1327-0027|FD-Score:34.00|P-value:6.12E-125 ID:SGTC_3063|Compound:1327-0034|FD-Score:35.20|P-value:3.88E-134 ID:SGTC_3064|Compound:1327-0027|FD-Score:27.30|P-value:1.61E-81 ID:SGTC_3100|Compound:9120536|FD-Score:5.15|P-value:1.47E-4 ID:SGTC_3219|Compound:9131112|FD-Score:4.42|P-value:9.22E-4 ID:SGTC_3243|Compound:9134147|FD-Score:-4.61|P-value:7.03E-4 ID:SGTC_3277|Compound:9138724|FD-Score:5.95|P-value:1.47E-5 ID:SGTC_3278|Compound:9139605|FD-Score:4.97|P-value:2.37E-4 ID:SGTC_3318|Compound:9139014|FD-Score:7.07|P-value:3.49E-7 ID:SGTC_3321|Compound:9137793|FD-Score:4.89|P-value:2.90E-4 ID:SGTC_3327|Compound:9140648|FD-Score:6.88|P-value:6.86E-7 ID:SGTC_9|Compound:0092-0002|FD-Score:4.78|P-value:3.83E-4 ID:SGTC_16|Compound:erodoxin|FD-Score:6.00|P-value:1.23E-5 ID:SGTC_22|Compound:0964-0034|FD-Score:6.47|P-value:2.80E-6 ID:SGTC_29|Compound:0299-0004|FD-Score:5.86|P-value:1.91E-5 ID:SGTC_35|Compound:0133-0054|FD-Score:-5.22|P-value:1.48E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:8.33|P-value:2.61E-9 ID:SGTC_40|Compound:0327-0103|FD-Score:-5.09|P-value:2.11E-4 ID:SGTC_58|Compound:0957-0393|FD-Score:7.74|P-value:2.80E-8 ID:SGTC_64|Compound:000l-0018|FD-Score:16.20|P-value:5.84E-30 ID:SGTC_70|Compound:0141-0289|FD-Score:-4.93|P-value:3.19E-4 ID:SGTC_86|Compound:0417-1630|FD-Score:15.40|P-value:2.68E-27 ID:SGTC_103|Compound:0844-0104|FD-Score:8.40|P-value:1.93E-9 ID:SGTC_107|Compound:0358-0022|FD-Score:14.20|P-value:1.89E-23 ID:SGTC_117|Compound:lucigenin|FD-Score:5.73|P-value:2.86E-5 ID:SGTC_129|Compound:0088-0017|FD-Score:-4.61|P-value:6.99E-4 ID:SGTC_137|Compound:0438-0332|FD-Score:25.80|P-value:6.99E-73 ID:SGTC_138|Compound:0850-0259|FD-Score:18.50|P-value:1.72E-38 ID:SGTC_142|Compound:0335-0849|FD-Score:33.70|P-value:2.36E-123 ID:SGTC_157|Compound:1348-1695|FD-Score:9.19|P-value:5.85E-11 ID:SGTC_158|Compound:k038-0087|FD-Score:16.70|P-value:5.66E-32 ID:SGTC_159|Compound:3970-0959|FD-Score:6.82|P-value:8.54E-7 ID:SGTC_163|Compound:1327-0036|FD-Score:22.20|P-value:7.88E-55 ID:SGTC_165|Compound:k038-0023|FD-Score:7.21|P-value:2.08E-7 ID:SGTC_168|Compound:3970-0862|FD-Score:8.50|P-value:1.26E-9 ID:SGTC_200|Compound:k038-0079|FD-Score:15.60|P-value:4.88E-28 ID:SGTC_207|Compound:4185-0010|FD-Score:-4.87|P-value:3.66E-4 ID:SGTC_208|Compound:k072-0098|FD-Score:9.16|P-value:6.83E-11 ID:SGTC_214|Compound:4373-3496|FD-Score:4.74|P-value:4.28E-4 ID:SGTC_216|Compound:k038-0035|FD-Score:19.80|P-value:6.51E-44 ID:SGTC_236|Compound:1509-0011|FD-Score:7.65|P-value:3.95E-8 ID:SGTC_248|Compound:streptozotocin|FD-Score:6.23|P-value:5.99E-6 ID:SGTC_268|Compound:camptothecin|FD-Score:19.90|P-value:1.52E-44 ID:SGTC_294|Compound:k038-0071|FD-Score:10.70|P-value:3.00E-14 ID:SGTC_332|Compound:4112-0506|FD-Score:12.10|P-value:1.41E-17 ID:SGTC_340|Compound:k038-0059|FD-Score:8.39|P-value:2.02E-9 ID:SGTC_351|Compound:caspofungin|FD-Score:6.22|P-value:6.22E-6 ID:SGTC_352|Compound:k048-0007|FD-Score:5.32|P-value:9.25E-5 ID:SGTC_354|Compound:2783-3500|FD-Score:5.12|P-value:1.59E-4 ID:SGTC_388|Compound:3',4'-dichloroisocoumarin|FD-Score:4.50|P-value:7.63E-4 ID:SGTC_394|Compound:menadione|FD-Score:4.64|P-value:5.43E-4 ID:SGTC_396|Compound:dithiazanine|FD-Score:7.57|P-value:5.45E-8 ID:SGTC_419|Compound:nsc-638432|FD-Score:-6.54|P-value:2.76E-6 ID:SGTC_431|Compound:k089-0097|FD-Score:-5.28|P-value:1.24E-4 ID:SGTC_451|Compound:chloral hydrate|FD-Score:14.70|P-value:4.59E-25 ID:SGTC_457|Compound:grayanotoxin iii|FD-Score:-4.75|P-value:4.97E-4 ID:SGTC_467|Compound:ro 31-8220|FD-Score:5.04|P-value:1.95E-4 ID:SGTC_525|Compound:k781-2675|FD-Score:14.00|P-value:4.34E-23 ID:SGTC_533|Compound:1222-0222|FD-Score:4.50|P-value:7.67E-4 ID:SGTC_546|Compound:peri-Naphthalide|FD-Score:7.13|P-value:2.75E-7 ID:SGTC_576|Compound:1073-0113|FD-Score:10.50|P-value:9.24E-14 ID:SGTC_580|Compound:1123-0028|FD-Score:17.20|P-value:9.84E-34 ID:SGTC_586|Compound:0957-0265|FD-Score:31.90|P-value:1.57E-110 ID:SGTC_630|Compound:4356-0227|FD-Score:4.85|P-value:3.20E-4 ID:SGTC_635|Compound:k038-0028|FD-Score:8.47|P-value:1.40E-9 ID:SGTC_673|Compound:1082-0474|FD-Score:15.80|P-value:1.34E-28 ID:SGTC_674|Compound:0498-0004|FD-Score:7.94|P-value:1.27E-8 ID:SGTC_707|Compound:0865-0008|FD-Score:5.09|P-value:1.72E-4 ID:SGTC_709|Compound:3807-1509|FD-Score:12.70|P-value:3.65E-19 ID:SGTC_721|Compound:1187-1332|FD-Score:4.80|P-value:3.61E-4 ID:SGTC_743|Compound:1275-0778|FD-Score:7.72|P-value:3.09E-8 ID:SGTC_759|Compound:3486-0358|FD-Score:7.16|P-value:2.50E-7 ID:SGTC_778|Compound:3456-2434|FD-Score:5.05|P-value:1.92E-4 ID:SGTC_788|Compound:1182-0090|FD-Score:5.49|P-value:5.67E-5 ID:SGTC_790|Compound:1575-0012|FD-Score:4.98|P-value:2.33E-4 ID:SGTC_794|Compound:k038-0031|FD-Score:15.00|P-value:6.04E-26 ID:SGTC_801|Compound:0866-0028|FD-Score:4.75|P-value:4.14E-4 ID:SGTC_817|Compound:1391-0715|FD-Score:5.92|P-value:1.62E-5 ID:SGTC_824|Compound:1304-0008|FD-Score:5.50|P-value:5.50E-5 ID:SGTC_829|Compound:1635-0120|FD-Score:15.20|P-value:8.33E-27 ID:SGTC_839|Compound:0122-0028|FD-Score:6.09|P-value:9.35E-6 ID:SGTC_851|Compound:0394-0702|FD-Score:5.82|P-value:2.17E-5 ID:SGTC_852|Compound:0418-0143|FD-Score:7.94|P-value:1.28E-8 ID:SGTC_871|Compound:0574-0004|FD-Score:7.84|P-value:1.88E-8 ID:SGTC_885|Compound:0865-0106|FD-Score:6.07|P-value:1.00E-5 ID:SGTC_943|Compound:3253-1379|FD-Score:-4.62|P-value:6.82E-4 ID:SGTC_984|Compound:1492-0255|FD-Score:8.16|P-value:5.19E-9 ID:SGTC_994|Compound:3910-0338|FD-Score:4.87|P-value:3.02E-4 ID:SGTC_1038|Compound:k292-0204|FD-Score:4.88|P-value:2.97E-4 ID:SGTC_1050|Compound:3232-1156|FD-Score:5.63|P-value:3.83E-5 ID:SGTC_1057|Compound:3448-5381|FD-Score:6.24|P-value:5.85E-6 ID:SGTC_1113|Compound:artemisinin|FD-Score:8.06|P-value:7.89E-9 ID:SGTC_1121|Compound:fusaric acid|FD-Score:6.37|P-value:3.83E-6 ID:SGTC_1133|Compound:3473-0247|FD-Score:5.70|P-value:3.10E-5 ID:SGTC_1161|Compound:k007-0610|FD-Score:14.40|P-value:2.40E-24 ID:SGTC_1188|Compound:1403-0014|FD-Score:7.18|P-value:2.37E-7 ID:SGTC_1197|Compound:1601-0112|FD-Score:4.44|P-value:8.88E-4 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.41|P-value:9.59E-4 ID:SGTC_1239|Compound:0337-0584|FD-Score:15.30|P-value:4.09E-27 ID:SGTC_1255|Compound:0566-0045|FD-Score:12.70|P-value:3.12E-19 ID:SGTC_1266|Compound:0828-0227|FD-Score:5.04|P-value:1.94E-4 ID:SGTC_1271|Compound:0832-2808|FD-Score:4.65|P-value:5.27E-4 ID:SGTC_1294|Compound:1000-1494|FD-Score:12.50|P-value:1.05E-18 ID:SGTC_1330|Compound:1469-0054|FD-Score:5.55|P-value:4.83E-5 ID:SGTC_1371|Compound:2421-0008|FD-Score:7.16|P-value:2.49E-7 ID:SGTC_1374|Compound:2889-5571|FD-Score:12.10|P-value:1.35E-17 ID:SGTC_1397|Compound:3532-0190|FD-Score:5.63|P-value:3.76E-5 ID:SGTC_1493|Compound:4348-0038|FD-Score:9.57|P-value:9.74E-12 ID:SGTC_1635|Compound:st007035|FD-Score:4.60|P-value:6.06E-4 ID:SGTC_1639|Compound:Lupinine o-methylbenzoicacid ester hydrochloride|FD-Score:5.76|P-value:2.60E-5 ID:SGTC_1652|Compound:st011932|FD-Score:11.10|P-value:3.38E-15 ID:SGTC_1696|Compound:st025591|FD-Score:6.16|P-value:7.45E-6 ID:SGTC_1750|Compound:st081859|FD-Score:9.64|P-value:7.02E-12 ID:SGTC_1797|Compound:st048695|FD-Score:5.01|P-value:2.12E-4 ID:SGTC_1851|Compound:st056236|FD-Score:4.97|P-value:2.37E-4 ID:SGTC_1900|Compound:st060200|FD-Score:-5.98|P-value:1.66E-5 ID:SGTC_1901|Compound:st060216|FD-Score:-4.83|P-value:4.09E-4 ID:SGTC_1902|Compound:st060212|FD-Score:-5.64|P-value:4.56E-5 ID:SGTC_1904|Compound:st060225|FD-Score:-4.60|P-value:7.18E-4 ID:SGTC_1905|Compound:st060207|FD-Score:-4.49|P-value:9.31E-4 ID:SGTC_1913|Compound:st060213|FD-Score:5.42|P-value:6.94E-5 ID:SGTC_1915|Compound:st067105|FD-Score:11.70|P-value:1.62E-16 ID:SGTC_1934|Compound:st074720|FD-Score:-4.77|P-value:4.75E-4 ID:SGTC_1968|Compound:st069590|FD-Score:18.00|P-value:1.07E-36 ID:SGTC_2038|Compound:4100038|FD-Score:-5.83|P-value:2.63E-5 ID:SGTC_2041|Compound:5107442|FD-Score:10.80|P-value:2.39E-14 ID:SGTC_2109|Compound:5483026|FD-Score:6.77|P-value:1.00E-6 ID:SGTC_2111|Compound:5486399|FD-Score:17.80|P-value:7.91E-36 ID:SGTC_2124|Compound:5246320|FD-Score:8.00|P-value:9.80E-9 ID:SGTC_2139|Compound:5578692|FD-Score:7.95|P-value:1.20E-8 ID:SGTC_2157|Compound:5649910|FD-Score:6.09|P-value:9.47E-6 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:6.59|P-value:1.85E-6 ID:SGTC_2186|Compound:6124449|FD-Score:6.67|P-value:1.40E-6 ID:SGTC_2225|Compound:6654152|FD-Score:6.91|P-value:6.21E-7 ID:SGTC_2229|Compound:7354935|FD-Score:6.93|P-value:5.64E-7 ID:SGTC_2233|Compound:sulbentine|FD-Score:7.35|P-value:1.24E-7 ID:SGTC_2249|Compound:haloperidol|FD-Score:-6.26|P-value:6.98E-6 ID:SGTC_2250|Compound:alverine citrate|FD-Score:-7.84|P-value:2.52E-8 ID:SGTC_2346|Compound:9031566|FD-Score:5.03|P-value:2.00E-4 ID:SGTC_2374|Compound:9071832|FD-Score:4.86|P-value:3.11E-4 ID:SGTC_2376|Compound:9072922|FD-Score:-4.84|P-value:4.01E-4 ID:SGTC_2380|Compound:9035439|FD-Score:7.27|P-value:1.69E-7 ID:SGTC_2396|Compound:5342950|FD-Score:15.10|P-value:2.51E-26 ID:SGTC_2400|Compound:5203494|FD-Score:7.01|P-value:4.36E-7 ID:SGTC_2408|Compound:sulbentine|FD-Score:6.89|P-value:6.48E-7 ID:SGTC_2410|Compound:aloe-emodin-8-o-glycoside|FD-Score:5.29|P-value:1.01E-4 ID:SGTC_2418|Compound:pentamidine|FD-Score:7.61|P-value:4.71E-8 ID:SGTC_2429|Compound:5902844|FD-Score:25.00|P-value:9.52E-69 ID:SGTC_2446|Compound:5162541|FD-Score:4.50|P-value:7.61E-4 ID:SGTC_2471|Compound:5466956|FD-Score:5.76|P-value:2.58E-5 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:5.43|P-value:6.80E-5 ID:SGTC_2534|Compound:helenine|FD-Score:12.40|P-value:1.64E-18 ID:SGTC_2539|Compound:epi(13)torulosol|FD-Score:-6.42|P-value:4.16E-6 ID:SGTC_2544|Compound:sphondin|FD-Score:6.63|P-value:1.64E-6 ID:SGTC_2575|Compound:plumbagin|FD-Score:7.01|P-value:4.24E-7 ID:SGTC_2582|Compound:agaric acid|FD-Score:7.56|P-value:5.67E-8 ID:SGTC_2586|Compound:curcumin|FD-Score:4.71|P-value:4.57E-4 ID:SGTC_2603|Compound:homopterocarpin|FD-Score:-5.95|P-value:1.82E-5 ID:SGTC_2609|Compound:2,3,4-trihydroxy-4'-ethoxybenzophenone|FD-Score:4.91|P-value:2.73E-4 ID:SGTC_2651|Compound:1327-0036|FD-Score:19.00|P-value:1.10E-40 ID:SGTC_2662|Compound:daunorubicin|FD-Score:7.23|P-value:1.94E-7 ID:SGTC_2679|Compound:rapamycin|FD-Score:-5.15|P-value:1.79E-4 ID:SGTC_2756|Compound:carbadox|FD-Score:6.36|P-value:3.91E-6 ID:SGTC_2759|Compound:disulfiram|FD-Score:5.00|P-value:2.15E-4 ID:SGTC_2867|Compound:9039098|FD-Score:-5.59|P-value:5.21E-5 ID:SGTC_2890|Compound:9046729|FD-Score:8.09|P-value:6.93E-9 ID:SGTC_2896|Compound:9052656|FD-Score:-4.94|P-value:3.09E-4 ID:SGTC_2912|Compound:7964298|FD-Score:9.63|P-value:7.44E-12 ID:SGTC_2928|Compound:9011484|FD-Score:5.58|P-value:4.38E-5 ID:SGTC_2980|Compound:9014342|FD-Score:4.73|P-value:4.39E-4 ID:SGTC_2997|Compound:9067075|FD-Score:6.91|P-value:6.05E-7 ID:SGTC_3026|Compound:9090633|FD-Score:-5.84|P-value:2.53E-5 ID:SGTC_3030|Compound:9087619|FD-Score:4.74|P-value:4.26E-4 ID:SGTC_3031|Compound:9088762|FD-Score:5.43|P-value:6.82E-5 ID:SGTC_3059|Compound:1327-0034|FD-Score:45.80|P-value:1.14E-224 ID:SGTC_3060|Compound:1327-0027|FD-Score:34.00|P-value:6.12E-125 ID:SGTC_3063|Compound:1327-0034|FD-Score:35.20|P-value:3.88E-134 ID:SGTC_3064|Compound:1327-0027|FD-Score:27.30|P-value:1.61E-81 ID:SGTC_3100|Compound:9120536|FD-Score:5.15|P-value:1.47E-4 ID:SGTC_3219|Compound:9131112|FD-Score:4.42|P-value:9.22E-4 ID:SGTC_3243|Compound:9134147|FD-Score:-4.61|P-value:7.03E-4 ID:SGTC_3277|Compound:9138724|FD-Score:5.95|P-value:1.47E-5 ID:SGTC_3278|Compound:9139605|FD-Score:4.97|P-value:2.37E-4 ID:SGTC_3318|Compound:9139014|FD-Score:7.07|P-value:3.49E-7 ID:SGTC_3321|Compound:9137793|FD-Score:4.89|P-value:2.90E-4 ID:SGTC_3327|Compound:9140648|FD-Score:6.88|P-value:6.86E-7

Top fitness defect scores for YPR107C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_3059 1327-0034 45.80 3.0 µM 1.14E-224 1 0 19.70
2 SGTC_3063 1327-0034 35.20 4.0 µM 3.88E-134 1 4.79E-272 15.10
3 SGTC_3060 1327-0027 34.00 12.5 µM 6.12E-125 1 3.22E-253 14.10
4 SGTC_142 0335-0849 33.70 62.7 µM 2.36E-123 ubiquinone biosynthesis & proteasome 1 5.69E-250 14.80
5 SGTC_586 0957-0265 31.90 8.2 µM 1.57E-110 cell wall 1 9.91E-224 8.48
6 SGTC_3064 1327-0027 27.30 10.0 µM 1.61E-81 1 2.26E-164 14.90
7 SGTC_137 0438-0332 25.80 85.4 µM 6.99E-73 ubiquinone biosynthesis & proteasome 1 1.04E-146 5.99
8 SGTC_2429 5902844 25.00 64.4 µM 9.52E-69 1 2.95E-138 13.30
9 SGTC_163 1327-0036 22.20 7.5 µM 7.88E-55 3 8.26E-110 2.84
10 SGTC_268 camptothecin 19.90 39.6 µM 1.52E-44 DNA damage response 1 8.37E-89 4.64
11 SGTC_216 k038-0035 19.80 28.4 µM 6.51E-44 ubiquinone biosynthesis & proteasome 1 1.64E-87 7.83
12 SGTC_2651 1327-0036 19.00 5.0 µM 1.10E-40 4 6.43E-81 4.47
13 SGTC_138 0850-0259 18.50 40.9 µM 1.72E-38 cell wall 1 1.92E-76 1.97
14 SGTC_1968 st069590 18.00 43.6 µM 1.07E-36 1 8.78E-73 4.18
15 SGTC_2111 5486399 17.80 200.0 µM 7.91E-36 1 5.20E-71 4.12
16 SGTC_580 1123-0028 17.20 41.0 µM 9.84E-34 DNA damage response 1 9.73E-67 8.47
17 SGTC_158 k038-0087 16.70 26.4 µM 5.66E-32 ubiquinone biosynthesis & proteasome 2 3.77E-63 4.87
18 SGTC_64 000l-0018 16.20 272.1 µM 5.84E-30 ubiquinone biosynthesis & proteasome 7 4.80E-59 2.27
19 SGTC_673 1082-0474 15.80 110.0 µM 1.34E-28 RSC complex & mRNA processing 2 2.84E-56 1.58
20 SGTC_200 k038-0079 15.60 37.5 µM 4.88E-28 ubiquinone biosynthesis & proteasome 1 3.96E-55 5.45

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.766 0 YGL093W SPC105 het Subunit of a kinetochore-microtubule binding complex with Kre28p that bridges centromeric heterochromatin and kinetochore MAPs and motors; required for sister chromatid bi-orientation and kinetochore binding of SAC components
0.481 8.10E-194 YDL183C YDL183C hom Mitochondrial inner-membrane protein thought to be involved in the formation of an active mitochondrial K+/H+ exchanger (KHE) system; non-essential gene
0.481 2.90E-193 YFR007W YFH7 hom Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases
0.460 4.21E-175 YER041W YEN1 hom Holliday junction resolvase; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1 and has similarity to S. cerevisiae endonuclease Rth1p
0.449 4.68E-166 YPR146C_d YPR146C_d hom Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
0.443 6.96E-161 YJL155C FBP26 hom Fructose-2,6-bisphosphatase, required for glucose metabolism; protein abundance increases in response to DNA replication stress
0.427 3.69E-148 YJL193W_p YJL193W_p hom Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect
0.423 1.79E-145 YDR537C_d YDR537C_d hom Dubious open reading frame unlikely to encode a protein, almost completely overlaps verified ORF PAD1/YDR538W
0.383 1.99E-117 YJR129C_p YJR129C_p hom Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
0.372 1.04E-110 YCL014W BUD3 hom Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
0.359 1.09E-102 YML034W SRC1 hom Inner nuclear membrane protein; functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has aneuploidy tolerance
0.347 1.02E-95 YNR016C ACC1 het Acetyl-CoA carboxylase, biotin containing enzyme; catalyzes the carboxylation of cytosolic acetyl-CoA to form malonyl-CoA and regulates histone acetylation by regulating the availablity of acetyl-CoA; required for de novo biosynthesis of long-chain fatty acids;
0.341 1.11E-91 YER019C-A SBH2 hom Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
0.340 1.73E-91 YLR033W RSC58 het Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance
0.326 5.23E-84 YER165W PAB1 het Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G