YGL026C / TRP5

Tryptophan synthase, catalyzes the last step of tryptophan biosynthesis; regulated by the general control system of amino acid biosynthesis

Zygosity: Homozygous strain
fixedexpanded
Profile for YGL026C / TRP5

Click on Significant Values for Screen Details ID:SGTC_10|Compound:0279-0212|FD-Score:8.74|P-value:2.57E-12 ID:SGTC_14|Compound:0354-0009|FD-Score:5.13|P-value:3.05E-5 ID:SGTC_19|Compound:0279-0214|FD-Score:6.45|P-value:2.06E-7 ID:SGTC_41|Compound:0478-0632|FD-Score:4.49|P-value:2.35E-4 ID:SGTC_50|Compound:0929-0078|FD-Score:9.76|P-value:5.98E-15 ID:SGTC_51|Compound:1013-0126|FD-Score:10.40|P-value:7.84E-17 ID:SGTC_58|Compound:0957-0393|FD-Score:-4.02|P-value:4.47E-4 ID:SGTC_79|Compound:0052-0007|FD-Score:11.10|P-value:7.73E-19 ID:SGTC_87|Compound:0100-0052|FD-Score:5.68|P-value:4.33E-6 ID:SGTC_109|Compound:0132-0036|FD-Score:4.14|P-value:6.52E-4 ID:SGTC_110|Compound:0850-0284|FD-Score:4.03|P-value:8.78E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:21.40|P-value:2.80E-65 ID:SGTC_134|Compound:0269-0018|FD-Score:9.27|P-value:1.21E-13 ID:SGTC_149|Compound:3970-0822|FD-Score:5.86|P-value:2.21E-6 ID:SGTC_152|Compound:4469-0003|FD-Score:4.84|P-value:7.89E-5 ID:SGTC_161|Compound:4065-0411|FD-Score:12.30|P-value:1.02E-22 ID:SGTC_167|Compound:3672-0051|FD-Score:4.07|P-value:7.83E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:7.92|P-value:2.12E-10 ID:SGTC_201|Compound:4262-0159|FD-Score:4.21|P-value:5.37E-4 ID:SGTC_207|Compound:4185-0010|FD-Score:10.20|P-value:2.74E-16 ID:SGTC_221|Compound:trifluoperazine|FD-Score:-4.50|P-value:1.06E-4 ID:SGTC_253|Compound:dyclonine|FD-Score:8.63|P-value:4.86E-12 ID:SGTC_278|Compound:4092-0821|FD-Score:5.61|P-value:5.63E-6 ID:SGTC_298|Compound:1391-0729|FD-Score:4.96|P-value:5.32E-5 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.12|P-value:3.34E-4 ID:SGTC_320|Compound:4092-0846|FD-Score:6.59|P-value:1.12E-7 ID:SGTC_332|Compound:4112-0506|FD-Score:5.57|P-value:6.37E-6 ID:SGTC_337|Compound:1315-0038|FD-Score:6.84|P-value:3.82E-8 ID:SGTC_346|Compound:4513-0042|FD-Score:4.06|P-value:8.08E-4 ID:SGTC_371|Compound:0195-0006|FD-Score:5.08|P-value:3.63E-5 ID:SGTC_386|Compound:1509-0011|FD-Score:7.82|P-value:3.55E-10 ID:SGTC_398|Compound:bronopol|FD-Score:-3.80|P-value:8.29E-4 ID:SGTC_409|Compound:arachidonic acid|FD-Score:5.04|P-value:4.09E-5 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:5.24|P-value:2.11E-5 ID:SGTC_434|Compound:1-hexadecyl-2-methylglycero-3 PC|FD-Score:5.09|P-value:3.46E-5 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:7.57|P-value:1.26E-9 ID:SGTC_505|Compound:gw-5074|FD-Score:15.90|P-value:4.00E-37 ID:SGTC_514|Compound:4466-0038|FD-Score:-5.06|P-value:1.62E-5 ID:SGTC_515|Compound:4092-1064|FD-Score:12.10|P-value:3.73E-22 ID:SGTC_518|Compound:1021-0119|FD-Score:6.96|P-value:2.20E-8 ID:SGTC_523|Compound:1934-0222|FD-Score:8.82|P-value:1.64E-12 ID:SGTC_526|Compound:4469-0568|FD-Score:6.91|P-value:2.79E-8 ID:SGTC_542|Compound:3381-0244|FD-Score:7.09|P-value:1.21E-8 ID:SGTC_543|Compound:3844-1095|FD-Score:6.43|P-value:2.22E-7 ID:SGTC_568|Compound:1193-0097|FD-Score:4.82|P-value:8.43E-5 ID:SGTC_581|Compound:0958-0271|FD-Score:7.37|P-value:3.32E-9 ID:SGTC_596|Compound:1155-0152|FD-Score:4.75|P-value:1.07E-4 ID:SGTC_601|Compound:0986-0029|FD-Score:5.06|P-value:3.87E-5 ID:SGTC_609|Compound:0986-0026|FD-Score:4.84|P-value:7.96E-5 ID:SGTC_614|Compound:0462-0418|FD-Score:4.08|P-value:7.78E-4 ID:SGTC_621|Compound:3584-0052|FD-Score:5.19|P-value:2.47E-5 ID:SGTC_637|Compound:1181-0519|FD-Score:11.10|P-value:7.22E-19 ID:SGTC_639|Compound:0833-0042|FD-Score:6.28|P-value:4.07E-7 ID:SGTC_651|Compound:3253-0966|FD-Score:4.64|P-value:1.52E-4 ID:SGTC_658|Compound:3253-0951|FD-Score:5.11|P-value:3.22E-5 ID:SGTC_666|Compound:0272-0154|FD-Score:4.23|P-value:5.13E-4 ID:SGTC_668|Compound:1682-0499|FD-Score:5.65|P-value:4.87E-6 ID:SGTC_748|Compound:0136-0228|FD-Score:4.91|P-value:6.38E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:6.59|P-value:1.12E-7 ID:SGTC_764|Compound:1951-2361|FD-Score:6.95|P-value:2.34E-8 ID:SGTC_767|Compound:0929-0023|FD-Score:12.60|P-value:1.02E-23 ID:SGTC_768|Compound:0384-0033|FD-Score:16.10|P-value:7.49E-38 ID:SGTC_800|Compound:3448-7362|FD-Score:3.99|P-value:9.84E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:9.64|P-value:1.24E-14 ID:SGTC_821|Compound:1114-0266|FD-Score:5.00|P-value:4.77E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:10.70|P-value:1.33E-17 ID:SGTC_834|Compound:0312-0008|FD-Score:5.02|P-value:4.46E-5 ID:SGTC_845|Compound:0330-0138|FD-Score:5.15|P-value:2.91E-5 ID:SGTC_860|Compound:0443-0016|FD-Score:6.16|P-value:6.61E-7 ID:SGTC_878|Compound:0828-0289|FD-Score:4.00|P-value:9.61E-4 ID:SGTC_890|Compound:0929-0006|FD-Score:5.46|P-value:9.71E-6 ID:SGTC_892|Compound:0929-0076|FD-Score:4.48|P-value:2.43E-4 ID:SGTC_943|Compound:3253-1379|FD-Score:4.74|P-value:1.10E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:-3.90|P-value:6.28E-4 ID:SGTC_1011|Compound:4112-3381|FD-Score:5.48|P-value:9.03E-6 ID:SGTC_1019|Compound:4262-0212|FD-Score:5.83|P-value:2.49E-6 ID:SGTC_1047|Compound:2043-3044|FD-Score:6.69|P-value:7.32E-8 ID:SGTC_1058|Compound:3448-5425|FD-Score:5.01|P-value:4.62E-5 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.40|P-value:3.14E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:4.57|P-value:1.87E-4 ID:SGTC_1076|Compound:itraconazole|FD-Score:7.26|P-value:5.40E-9 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.66|P-value:1.43E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:9.76|P-value:5.76E-15 ID:SGTC_1130|Compound:3454-2858|FD-Score:4.14|P-value:6.58E-4 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:5.13|P-value:3.05E-5 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.78|P-value:9.73E-5 ID:SGTC_1212|Compound:0520-0165|FD-Score:4.44|P-value:2.71E-4 ID:SGTC_1213|Compound:1315-0166|FD-Score:6.02|P-value:1.16E-6 ID:SGTC_1219|Compound:1469-0211|FD-Score:14.10|P-value:3.36E-29 ID:SGTC_1225|Compound:1216-0074|FD-Score:8.36|P-value:2.09E-11 ID:SGTC_1241|Compound:0364-0022|FD-Score:4.91|P-value:6.32E-5 ID:SGTC_1252|Compound:0493-0875|FD-Score:4.62|P-value:1.61E-4 ID:SGTC_1279|Compound:0874-0590|FD-Score:5.12|P-value:3.20E-5 ID:SGTC_1284|Compound:0929-0043|FD-Score:6.11|P-value:8.05E-7 ID:SGTC_1304|Compound:1165-0502|FD-Score:12.00|P-value:1.18E-21 ID:SGTC_1313|Compound:1220-0047|FD-Score:4.30|P-value:4.14E-4 ID:SGTC_1335|Compound:1486-0900|FD-Score:6.45|P-value:2.03E-7 ID:SGTC_1338|Compound:1486-1223|FD-Score:4.19|P-value:5.67E-4 ID:SGTC_1350|Compound:1495-0454|FD-Score:7.93|P-value:2.02E-10 ID:SGTC_1352|Compound:1496-0991|FD-Score:4.03|P-value:8.93E-4 ID:SGTC_1360|Compound:1598-0022|FD-Score:5.28|P-value:1.84E-5 ID:SGTC_1366|Compound:1683-0113|FD-Score:5.06|P-value:3.88E-5 ID:SGTC_1418|Compound:3966-3099|FD-Score:5.14|P-value:2.97E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:4.55|P-value:1.99E-4 ID:SGTC_1427|Compound:4048-4900|FD-Score:4.24|P-value:4.92E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:8.16|P-value:6.01E-11 ID:SGTC_1482|Compound:3346-2049|FD-Score:5.20|P-value:2.44E-5 ID:SGTC_1566|Compound:6,7-dimethoxy-4-ethylcoumarin|FD-Score:4.78|P-value:9.82E-5 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:8.87|P-value:1.26E-12 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:5.37|P-value:1.34E-5 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:5.27|P-value:1.91E-5 ID:SGTC_1603|Compound:st002045|FD-Score:7.63|P-value:9.23E-10 ID:SGTC_1617|Compound:st002906|FD-Score:9.66|P-value:1.08E-14 ID:SGTC_1636|Compound:st007707|FD-Score:12.30|P-value:1.19E-22 ID:SGTC_1649|Compound:st011737|FD-Score:7.87|P-value:2.80E-10 ID:SGTC_1672|Compound:st016598|FD-Score:5.16|P-value:2.80E-5 ID:SGTC_1673|Compound:st016611|FD-Score:11.40|P-value:1.14E-19 ID:SGTC_1697|Compound:st025554|FD-Score:7.63|P-value:9.08E-10 ID:SGTC_1699|Compound:st031318|FD-Score:6.52|P-value:1.54E-7 ID:SGTC_1710|Compound:st031758|FD-Score:4.81|P-value:8.68E-5 ID:SGTC_1715|Compound:st032160|FD-Score:12.60|P-value:6.46E-24 ID:SGTC_1726|Compound:st035556|FD-Score:8.09|P-value:8.80E-11 ID:SGTC_1750|Compound:st081859|FD-Score:7.28|P-value:5.07E-9 ID:SGTC_1757|Compound:st041620|FD-Score:5.32|P-value:1.59E-5 ID:SGTC_1797|Compound:st048695|FD-Score:10.70|P-value:1.11E-17 ID:SGTC_1818|Compound:st052136|FD-Score:-4.40|P-value:1.44E-4 ID:SGTC_1824|Compound:st053723|FD-Score:8.68|P-value:3.73E-12 ID:SGTC_1835|Compound:st008666|FD-Score:5.17|P-value:2.64E-5 ID:SGTC_1847|Compound:st056231|FD-Score:5.05|P-value:4.00E-5 ID:SGTC_1881|Compound:5652484|FD-Score:15.80|P-value:1.90E-36 ID:SGTC_1882|Compound:5615643|FD-Score:16.60|P-value:4.63E-40 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:22.60|P-value:8.22E-73 ID:SGTC_1902|Compound:st060212|FD-Score:4.95|P-value:5.59E-5 ID:SGTC_1906|Compound:st060206|FD-Score:5.50|P-value:8.48E-6 ID:SGTC_1909|Compound:st060837|FD-Score:4.24|P-value:4.89E-4 ID:SGTC_1921|Compound:5740136|FD-Score:5.63|P-value:5.13E-6 ID:SGTC_1933|Compound:st074711|FD-Score:5.72|P-value:3.67E-6 ID:SGTC_1937|Compound:st074714|FD-Score:8.82|P-value:1.66E-12 ID:SGTC_1999|Compound:st074831|FD-Score:5.78|P-value:3.00E-6 ID:SGTC_2013|Compound:4024628|FD-Score:8.22|P-value:4.56E-11 ID:SGTC_2019|Compound:4016004|FD-Score:-5.95|P-value:5.50E-7 ID:SGTC_2021|Compound:4019055|FD-Score:-3.87|P-value:6.83E-4 ID:SGTC_2024|Compound:5144227|FD-Score:11.00|P-value:1.06E-18 ID:SGTC_2036|Compound:5160441|FD-Score:12.00|P-value:1.26E-21 ID:SGTC_2038|Compound:4100038|FD-Score:14.20|P-value:5.69E-30 ID:SGTC_2050|Compound:5263056|FD-Score:5.80|P-value:2.71E-6 ID:SGTC_2056|Compound:5235370|FD-Score:15.80|P-value:2.08E-36 ID:SGTC_2086|Compound:5274770|FD-Score:5.01|P-value:4.53E-5 ID:SGTC_2093|Compound:5331342|FD-Score:8.57|P-value:6.65E-12 ID:SGTC_2118|Compound:5526350|FD-Score:5.78|P-value:2.92E-6 ID:SGTC_2137|Compound:5261020|FD-Score:6.75|P-value:5.54E-8 ID:SGTC_2197|Compound:6588183|FD-Score:6.50|P-value:1.67E-7 ID:SGTC_2198|Compound:6589944|FD-Score:5.98|P-value:1.37E-6 ID:SGTC_2231|Compound:micatex|FD-Score:5.06|P-value:3.83E-5 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:19.40|P-value:7.13E-54 ID:SGTC_2254|Compound:7938975|FD-Score:6.89|P-value:2.99E-8 ID:SGTC_2286|Compound:7945697|FD-Score:4.70|P-value:1.23E-4 ID:SGTC_2301|Compound:7769476|FD-Score:5.57|P-value:6.38E-6 ID:SGTC_2376|Compound:9072922|FD-Score:4.56|P-value:1.90E-4 ID:SGTC_2384|Compound:9036245|FD-Score:10.80|P-value:6.56E-18 ID:SGTC_2409|Compound:alverine citrate|FD-Score:5.09|P-value:3.50E-5 ID:SGTC_2428|Compound:5615643|FD-Score:10.80|P-value:5.20E-18 ID:SGTC_2433|Compound:5607874|FD-Score:6.10|P-value:8.43E-7 ID:SGTC_2437|Compound:5741531|FD-Score:6.49|P-value:1.68E-7 ID:SGTC_2445|Compound:5742597|FD-Score:7.49|P-value:1.80E-9 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:6.88|P-value:3.08E-8 ID:SGTC_2468|Compound:5987765|FD-Score:5.27|P-value:1.89E-5 ID:SGTC_2472|Compound:5377652|FD-Score:14.90|P-value:1.34E-32 ID:SGTC_2478|Compound:5763493|FD-Score:10.70|P-value:1.12E-17 ID:SGTC_2486|Compound:5283202|FD-Score:6.09|P-value:8.76E-7 ID:SGTC_2488|Compound:5268135|FD-Score:8.09|P-value:9.08E-11 ID:SGTC_2524|Compound:avocatin b|FD-Score:4.56|P-value:1.89E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:15.70|P-value:4.88E-36 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:6.80|P-value:4.43E-8 ID:SGTC_2607|Compound:solasodine|FD-Score:14.80|P-value:4.17E-32 ID:SGTC_2616|Compound:abietic acid|FD-Score:4.90|P-value:6.62E-5 ID:SGTC_2618|Compound:avocadyne|FD-Score:9.15|P-value:2.46E-13 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:5.46|P-value:9.84E-6 ID:SGTC_2650|Compound:prasterone|FD-Score:7.78|P-value:4.39E-10 ID:SGTC_2678|Compound:equilin|FD-Score:5.97|P-value:1.44E-6 ID:SGTC_2688|Compound:kanamycin b|FD-Score:5.86|P-value:2.20E-6 ID:SGTC_2689|Compound:tacrolimus|FD-Score:5.36|P-value:1.36E-5 ID:SGTC_2725|Compound:haloperidol|FD-Score:9.42|P-value:4.86E-14 ID:SGTC_2733|Compound:amorolfine|FD-Score:5.88|P-value:2.02E-6 ID:SGTC_2735|Compound:sertaconazole|FD-Score:7.45|P-value:2.21E-9 ID:SGTC_2741|Compound:miltefosine|FD-Score:4.87|P-value:7.33E-5 ID:SGTC_2752|Compound:diclazuril|FD-Score:4.97|P-value:5.19E-5 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:10.50|P-value:5.21E-17 ID:SGTC_2776|Compound:terbinafine|FD-Score:15.90|P-value:9.41E-37 ID:SGTC_2777|Compound:climbazole|FD-Score:4.55|P-value:2.00E-4 ID:SGTC_2778|Compound:tioconazole|FD-Score:12.20|P-value:2.00E-22 ID:SGTC_2807|Compound:7945238|FD-Score:-4.10|P-value:3.52E-4 ID:SGTC_2810|Compound:7959871|FD-Score:-3.79|P-value:8.41E-4 ID:SGTC_2812|Compound:7970281|FD-Score:-3.85|P-value:7.19E-4 ID:SGTC_2925|Compound:9010536|FD-Score:5.53|P-value:7.63E-6 ID:SGTC_2948|Compound:9070189|FD-Score:8.68|P-value:3.59E-12 ID:SGTC_2974|Compound:9094440|FD-Score:6.13|P-value:7.51E-7 ID:SGTC_3018|Compound:9082602|FD-Score:7.21|P-value:7.00E-9 ID:SGTC_3250|Compound:9135583|FD-Score:4.49|P-value:2.40E-4 ID:SGTC_3307|Compound:9126885|FD-Score:4.16|P-value:6.17E-4 ID:SGTC_3308|Compound:9128332|FD-Score:27.90|P-value:3.03E-110 ID:SGTC_3317|Compound:9138495|FD-Score:7.53|P-value:1.49E-9 ID:SGTC_3318|Compound:9139014|FD-Score:6.65|P-value:8.70E-8 ID:SGTC_10|Compound:0279-0212|FD-Score:8.74|P-value:2.57E-12 ID:SGTC_14|Compound:0354-0009|FD-Score:5.13|P-value:3.05E-5 ID:SGTC_19|Compound:0279-0214|FD-Score:6.45|P-value:2.06E-7 ID:SGTC_41|Compound:0478-0632|FD-Score:4.49|P-value:2.35E-4 ID:SGTC_50|Compound:0929-0078|FD-Score:9.76|P-value:5.98E-15 ID:SGTC_51|Compound:1013-0126|FD-Score:10.40|P-value:7.84E-17 ID:SGTC_58|Compound:0957-0393|FD-Score:-4.02|P-value:4.47E-4 ID:SGTC_79|Compound:0052-0007|FD-Score:11.10|P-value:7.73E-19 ID:SGTC_87|Compound:0100-0052|FD-Score:5.68|P-value:4.33E-6 ID:SGTC_109|Compound:0132-0036|FD-Score:4.14|P-value:6.52E-4 ID:SGTC_110|Compound:0850-0284|FD-Score:4.03|P-value:8.78E-4 ID:SGTC_129|Compound:0088-0017|FD-Score:21.40|P-value:2.80E-65 ID:SGTC_134|Compound:0269-0018|FD-Score:9.27|P-value:1.21E-13 ID:SGTC_149|Compound:3970-0822|FD-Score:5.86|P-value:2.21E-6 ID:SGTC_152|Compound:4469-0003|FD-Score:4.84|P-value:7.89E-5 ID:SGTC_161|Compound:4065-0411|FD-Score:12.30|P-value:1.02E-22 ID:SGTC_167|Compound:3672-0051|FD-Score:4.07|P-value:7.83E-4 ID:SGTC_180|Compound:1486-1293|FD-Score:7.92|P-value:2.12E-10 ID:SGTC_201|Compound:4262-0159|FD-Score:4.21|P-value:5.37E-4 ID:SGTC_207|Compound:4185-0010|FD-Score:10.20|P-value:2.74E-16 ID:SGTC_221|Compound:trifluoperazine|FD-Score:-4.50|P-value:1.06E-4 ID:SGTC_253|Compound:dyclonine|FD-Score:8.63|P-value:4.86E-12 ID:SGTC_278|Compound:4092-0821|FD-Score:5.61|P-value:5.63E-6 ID:SGTC_298|Compound:1391-0729|FD-Score:4.96|P-value:5.32E-5 ID:SGTC_310|Compound:1273-0058|FD-Score:-4.12|P-value:3.34E-4 ID:SGTC_320|Compound:4092-0846|FD-Score:6.59|P-value:1.12E-7 ID:SGTC_332|Compound:4112-0506|FD-Score:5.57|P-value:6.37E-6 ID:SGTC_337|Compound:1315-0038|FD-Score:6.84|P-value:3.82E-8 ID:SGTC_346|Compound:4513-0042|FD-Score:4.06|P-value:8.08E-4 ID:SGTC_371|Compound:0195-0006|FD-Score:5.08|P-value:3.63E-5 ID:SGTC_386|Compound:1509-0011|FD-Score:7.82|P-value:3.55E-10 ID:SGTC_398|Compound:bronopol|FD-Score:-3.80|P-value:8.29E-4 ID:SGTC_409|Compound:arachidonic acid|FD-Score:5.04|P-value:4.09E-5 ID:SGTC_410|Compound:α-linolenic acid|FD-Score:5.24|P-value:2.11E-5 ID:SGTC_434|Compound:1-hexadecyl-2-methylglycero-3 PC|FD-Score:5.09|P-value:3.46E-5 ID:SGTC_474|Compound:dl-dihydrosphingosine|FD-Score:7.57|P-value:1.26E-9 ID:SGTC_505|Compound:gw-5074|FD-Score:15.90|P-value:4.00E-37 ID:SGTC_514|Compound:4466-0038|FD-Score:-5.06|P-value:1.62E-5 ID:SGTC_515|Compound:4092-1064|FD-Score:12.10|P-value:3.73E-22 ID:SGTC_518|Compound:1021-0119|FD-Score:6.96|P-value:2.20E-8 ID:SGTC_523|Compound:1934-0222|FD-Score:8.82|P-value:1.64E-12 ID:SGTC_526|Compound:4469-0568|FD-Score:6.91|P-value:2.79E-8 ID:SGTC_542|Compound:3381-0244|FD-Score:7.09|P-value:1.21E-8 ID:SGTC_543|Compound:3844-1095|FD-Score:6.43|P-value:2.22E-7 ID:SGTC_568|Compound:1193-0097|FD-Score:4.82|P-value:8.43E-5 ID:SGTC_581|Compound:0958-0271|FD-Score:7.37|P-value:3.32E-9 ID:SGTC_596|Compound:1155-0152|FD-Score:4.75|P-value:1.07E-4 ID:SGTC_601|Compound:0986-0029|FD-Score:5.06|P-value:3.87E-5 ID:SGTC_609|Compound:0986-0026|FD-Score:4.84|P-value:7.96E-5 ID:SGTC_614|Compound:0462-0418|FD-Score:4.08|P-value:7.78E-4 ID:SGTC_621|Compound:3584-0052|FD-Score:5.19|P-value:2.47E-5 ID:SGTC_637|Compound:1181-0519|FD-Score:11.10|P-value:7.22E-19 ID:SGTC_639|Compound:0833-0042|FD-Score:6.28|P-value:4.07E-7 ID:SGTC_651|Compound:3253-0966|FD-Score:4.64|P-value:1.52E-4 ID:SGTC_658|Compound:3253-0951|FD-Score:5.11|P-value:3.22E-5 ID:SGTC_666|Compound:0272-0154|FD-Score:4.23|P-value:5.13E-4 ID:SGTC_668|Compound:1682-0499|FD-Score:5.65|P-value:4.87E-6 ID:SGTC_748|Compound:0136-0228|FD-Score:4.91|P-value:6.38E-5 ID:SGTC_755|Compound:1995-0008|FD-Score:6.59|P-value:1.12E-7 ID:SGTC_764|Compound:1951-2361|FD-Score:6.95|P-value:2.34E-8 ID:SGTC_767|Compound:0929-0023|FD-Score:12.60|P-value:1.02E-23 ID:SGTC_768|Compound:0384-0033|FD-Score:16.10|P-value:7.49E-38 ID:SGTC_800|Compound:3448-7362|FD-Score:3.99|P-value:9.84E-4 ID:SGTC_819|Compound:1013-0258|FD-Score:9.64|P-value:1.24E-14 ID:SGTC_821|Compound:1114-0266|FD-Score:5.00|P-value:4.77E-5 ID:SGTC_823|Compound:0417-1665|FD-Score:10.70|P-value:1.33E-17 ID:SGTC_834|Compound:0312-0008|FD-Score:5.02|P-value:4.46E-5 ID:SGTC_845|Compound:0330-0138|FD-Score:5.15|P-value:2.91E-5 ID:SGTC_860|Compound:0443-0016|FD-Score:6.16|P-value:6.61E-7 ID:SGTC_878|Compound:0828-0289|FD-Score:4.00|P-value:9.61E-4 ID:SGTC_890|Compound:0929-0006|FD-Score:5.46|P-value:9.71E-6 ID:SGTC_892|Compound:0929-0076|FD-Score:4.48|P-value:2.43E-4 ID:SGTC_943|Compound:3253-1379|FD-Score:4.74|P-value:1.10E-4 ID:SGTC_951|Compound:1171-0579|FD-Score:-3.90|P-value:6.28E-4 ID:SGTC_1011|Compound:4112-3381|FD-Score:5.48|P-value:9.03E-6 ID:SGTC_1019|Compound:4262-0212|FD-Score:5.83|P-value:2.49E-6 ID:SGTC_1047|Compound:2043-3044|FD-Score:6.69|P-value:7.32E-8 ID:SGTC_1058|Compound:3448-5425|FD-Score:5.01|P-value:4.62E-5 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.40|P-value:3.14E-4 ID:SGTC_1072|Compound:oxiconazole|FD-Score:4.57|P-value:1.87E-4 ID:SGTC_1076|Compound:itraconazole|FD-Score:7.26|P-value:5.40E-9 ID:SGTC_1088|Compound:bifonazole|FD-Score:4.66|P-value:1.43E-4 ID:SGTC_1104|Compound:tacrolimus|FD-Score:9.76|P-value:5.76E-15 ID:SGTC_1130|Compound:3454-2858|FD-Score:4.14|P-value:6.58E-4 ID:SGTC_1135|Compound:dihydrocapsaicin|FD-Score:5.13|P-value:3.05E-5 ID:SGTC_1191|Compound:1487-1166|FD-Score:4.78|P-value:9.73E-5 ID:SGTC_1212|Compound:0520-0165|FD-Score:4.44|P-value:2.71E-4 ID:SGTC_1213|Compound:1315-0166|FD-Score:6.02|P-value:1.16E-6 ID:SGTC_1219|Compound:1469-0211|FD-Score:14.10|P-value:3.36E-29 ID:SGTC_1225|Compound:1216-0074|FD-Score:8.36|P-value:2.09E-11 ID:SGTC_1241|Compound:0364-0022|FD-Score:4.91|P-value:6.32E-5 ID:SGTC_1252|Compound:0493-0875|FD-Score:4.62|P-value:1.61E-4 ID:SGTC_1279|Compound:0874-0590|FD-Score:5.12|P-value:3.20E-5 ID:SGTC_1284|Compound:0929-0043|FD-Score:6.11|P-value:8.05E-7 ID:SGTC_1304|Compound:1165-0502|FD-Score:12.00|P-value:1.18E-21 ID:SGTC_1313|Compound:1220-0047|FD-Score:4.30|P-value:4.14E-4 ID:SGTC_1335|Compound:1486-0900|FD-Score:6.45|P-value:2.03E-7 ID:SGTC_1338|Compound:1486-1223|FD-Score:4.19|P-value:5.67E-4 ID:SGTC_1350|Compound:1495-0454|FD-Score:7.93|P-value:2.02E-10 ID:SGTC_1352|Compound:1496-0991|FD-Score:4.03|P-value:8.93E-4 ID:SGTC_1360|Compound:1598-0022|FD-Score:5.28|P-value:1.84E-5 ID:SGTC_1366|Compound:1683-0113|FD-Score:5.06|P-value:3.88E-5 ID:SGTC_1418|Compound:3966-3099|FD-Score:5.14|P-value:2.97E-5 ID:SGTC_1424|Compound:4048-1941|FD-Score:4.55|P-value:1.99E-4 ID:SGTC_1427|Compound:4048-4900|FD-Score:4.24|P-value:4.92E-4 ID:SGTC_1455|Compound:4262-0120|FD-Score:8.16|P-value:6.01E-11 ID:SGTC_1482|Compound:3346-2049|FD-Score:5.20|P-value:2.44E-5 ID:SGTC_1566|Compound:6,7-dimethoxy-4-ethylcoumarin|FD-Score:4.78|P-value:9.82E-5 ID:SGTC_1572|Compound:epiandrosterone|FD-Score:8.87|P-value:1.26E-12 ID:SGTC_1593|Compound:justicidin b . 9-(1,3-benzodioxol-5-yl)- 6,7-dimethoxynaphtho[2,3-c]furan-1(3h)-one|FD-Score:5.37|P-value:1.34E-5 ID:SGTC_1597|Compound:7-benzyloxygramine|FD-Score:5.27|P-value:1.91E-5 ID:SGTC_1603|Compound:st002045|FD-Score:7.63|P-value:9.23E-10 ID:SGTC_1617|Compound:st002906|FD-Score:9.66|P-value:1.08E-14 ID:SGTC_1636|Compound:st007707|FD-Score:12.30|P-value:1.19E-22 ID:SGTC_1649|Compound:st011737|FD-Score:7.87|P-value:2.80E-10 ID:SGTC_1672|Compound:st016598|FD-Score:5.16|P-value:2.80E-5 ID:SGTC_1673|Compound:st016611|FD-Score:11.40|P-value:1.14E-19 ID:SGTC_1697|Compound:st025554|FD-Score:7.63|P-value:9.08E-10 ID:SGTC_1699|Compound:st031318|FD-Score:6.52|P-value:1.54E-7 ID:SGTC_1710|Compound:st031758|FD-Score:4.81|P-value:8.68E-5 ID:SGTC_1715|Compound:st032160|FD-Score:12.60|P-value:6.46E-24 ID:SGTC_1726|Compound:st035556|FD-Score:8.09|P-value:8.80E-11 ID:SGTC_1750|Compound:st081859|FD-Score:7.28|P-value:5.07E-9 ID:SGTC_1757|Compound:st041620|FD-Score:5.32|P-value:1.59E-5 ID:SGTC_1797|Compound:st048695|FD-Score:10.70|P-value:1.11E-17 ID:SGTC_1818|Compound:st052136|FD-Score:-4.40|P-value:1.44E-4 ID:SGTC_1824|Compound:st053723|FD-Score:8.68|P-value:3.73E-12 ID:SGTC_1835|Compound:st008666|FD-Score:5.17|P-value:2.64E-5 ID:SGTC_1847|Compound:st056231|FD-Score:5.05|P-value:4.00E-5 ID:SGTC_1881|Compound:5652484|FD-Score:15.80|P-value:1.90E-36 ID:SGTC_1882|Compound:5615643|FD-Score:16.60|P-value:4.63E-40 ID:SGTC_1883|Compound:5-benzylidenerhodanine|FD-Score:22.60|P-value:8.22E-73 ID:SGTC_1902|Compound:st060212|FD-Score:4.95|P-value:5.59E-5 ID:SGTC_1906|Compound:st060206|FD-Score:5.50|P-value:8.48E-6 ID:SGTC_1909|Compound:st060837|FD-Score:4.24|P-value:4.89E-4 ID:SGTC_1921|Compound:5740136|FD-Score:5.63|P-value:5.13E-6 ID:SGTC_1933|Compound:st074711|FD-Score:5.72|P-value:3.67E-6 ID:SGTC_1937|Compound:st074714|FD-Score:8.82|P-value:1.66E-12 ID:SGTC_1999|Compound:st074831|FD-Score:5.78|P-value:3.00E-6 ID:SGTC_2013|Compound:4024628|FD-Score:8.22|P-value:4.56E-11 ID:SGTC_2019|Compound:4016004|FD-Score:-5.95|P-value:5.50E-7 ID:SGTC_2021|Compound:4019055|FD-Score:-3.87|P-value:6.83E-4 ID:SGTC_2024|Compound:5144227|FD-Score:11.00|P-value:1.06E-18 ID:SGTC_2036|Compound:5160441|FD-Score:12.00|P-value:1.26E-21 ID:SGTC_2038|Compound:4100038|FD-Score:14.20|P-value:5.69E-30 ID:SGTC_2050|Compound:5263056|FD-Score:5.80|P-value:2.71E-6 ID:SGTC_2056|Compound:5235370|FD-Score:15.80|P-value:2.08E-36 ID:SGTC_2086|Compound:5274770|FD-Score:5.01|P-value:4.53E-5 ID:SGTC_2093|Compound:5331342|FD-Score:8.57|P-value:6.65E-12 ID:SGTC_2118|Compound:5526350|FD-Score:5.78|P-value:2.92E-6 ID:SGTC_2137|Compound:5261020|FD-Score:6.75|P-value:5.54E-8 ID:SGTC_2197|Compound:6588183|FD-Score:6.50|P-value:1.67E-7 ID:SGTC_2198|Compound:6589944|FD-Score:5.98|P-value:1.37E-6 ID:SGTC_2231|Compound:micatex|FD-Score:5.06|P-value:3.83E-5 ID:SGTC_2232|Compound:chlorophetanol|FD-Score:19.40|P-value:7.13E-54 ID:SGTC_2254|Compound:7938975|FD-Score:6.89|P-value:2.99E-8 ID:SGTC_2286|Compound:7945697|FD-Score:4.70|P-value:1.23E-4 ID:SGTC_2301|Compound:7769476|FD-Score:5.57|P-value:6.38E-6 ID:SGTC_2376|Compound:9072922|FD-Score:4.56|P-value:1.90E-4 ID:SGTC_2384|Compound:9036245|FD-Score:10.80|P-value:6.56E-18 ID:SGTC_2409|Compound:alverine citrate|FD-Score:5.09|P-value:3.50E-5 ID:SGTC_2428|Compound:5615643|FD-Score:10.80|P-value:5.20E-18 ID:SGTC_2433|Compound:5607874|FD-Score:6.10|P-value:8.43E-7 ID:SGTC_2437|Compound:5741531|FD-Score:6.49|P-value:1.68E-7 ID:SGTC_2445|Compound:5742597|FD-Score:7.49|P-value:1.80E-9 ID:SGTC_2454|Compound:5-benzylidenerhodanine|FD-Score:6.88|P-value:3.08E-8 ID:SGTC_2468|Compound:5987765|FD-Score:5.27|P-value:1.89E-5 ID:SGTC_2472|Compound:5377652|FD-Score:14.90|P-value:1.34E-32 ID:SGTC_2478|Compound:5763493|FD-Score:10.70|P-value:1.12E-17 ID:SGTC_2486|Compound:5283202|FD-Score:6.09|P-value:8.76E-7 ID:SGTC_2488|Compound:5268135|FD-Score:8.09|P-value:9.08E-11 ID:SGTC_2524|Compound:avocatin b|FD-Score:4.56|P-value:1.89E-4 ID:SGTC_2540|Compound:epiandrosterone|FD-Score:15.70|P-value:4.88E-36 ID:SGTC_2567|Compound:aureobasidin a|FD-Score:6.80|P-value:4.43E-8 ID:SGTC_2607|Compound:solasodine|FD-Score:14.80|P-value:4.17E-32 ID:SGTC_2616|Compound:abietic acid|FD-Score:4.90|P-value:6.62E-5 ID:SGTC_2618|Compound:avocadyne|FD-Score:9.15|P-value:2.46E-13 ID:SGTC_2642|Compound:cholecalciferol|FD-Score:5.46|P-value:9.84E-6 ID:SGTC_2650|Compound:prasterone|FD-Score:7.78|P-value:4.39E-10 ID:SGTC_2678|Compound:equilin|FD-Score:5.97|P-value:1.44E-6 ID:SGTC_2688|Compound:kanamycin b|FD-Score:5.86|P-value:2.20E-6 ID:SGTC_2689|Compound:tacrolimus|FD-Score:5.36|P-value:1.36E-5 ID:SGTC_2725|Compound:haloperidol|FD-Score:9.42|P-value:4.86E-14 ID:SGTC_2733|Compound:amorolfine|FD-Score:5.88|P-value:2.02E-6 ID:SGTC_2735|Compound:sertaconazole|FD-Score:7.45|P-value:2.21E-9 ID:SGTC_2741|Compound:miltefosine|FD-Score:4.87|P-value:7.33E-5 ID:SGTC_2752|Compound:diclazuril|FD-Score:4.97|P-value:5.19E-5 ID:SGTC_2758|Compound:dehydroepiandrosterone|FD-Score:10.50|P-value:5.21E-17 ID:SGTC_2776|Compound:terbinafine|FD-Score:15.90|P-value:9.41E-37 ID:SGTC_2777|Compound:climbazole|FD-Score:4.55|P-value:2.00E-4 ID:SGTC_2778|Compound:tioconazole|FD-Score:12.20|P-value:2.00E-22 ID:SGTC_2807|Compound:7945238|FD-Score:-4.10|P-value:3.52E-4 ID:SGTC_2810|Compound:7959871|FD-Score:-3.79|P-value:8.41E-4 ID:SGTC_2812|Compound:7970281|FD-Score:-3.85|P-value:7.19E-4 ID:SGTC_2925|Compound:9010536|FD-Score:5.53|P-value:7.63E-6 ID:SGTC_2948|Compound:9070189|FD-Score:8.68|P-value:3.59E-12 ID:SGTC_2974|Compound:9094440|FD-Score:6.13|P-value:7.51E-7 ID:SGTC_3018|Compound:9082602|FD-Score:7.21|P-value:7.00E-9 ID:SGTC_3250|Compound:9135583|FD-Score:4.49|P-value:2.40E-4 ID:SGTC_3307|Compound:9126885|FD-Score:4.16|P-value:6.17E-4 ID:SGTC_3308|Compound:9128332|FD-Score:27.90|P-value:3.03E-110 ID:SGTC_3317|Compound:9138495|FD-Score:7.53|P-value:1.49E-9 ID:SGTC_3318|Compound:9139014|FD-Score:6.65|P-value:8.70E-8

Top fitness defect scores for YGL026C deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
1 SGTC_3308 9128332 27.90 17.6 µM 3.03E-110 plasma membrane duress 3 5.43E-172
2 SGTC_1883 5-benzylidenerhodanine 22.60 20.0 µM 8.22E-73 TRP & mitochondrial translation 3 1.94E-113
3 SGTC_129 0088-0017 21.40 176.6 µM 2.80E-65 2 1.19E-101
4 SGTC_2232 chlorophetanol 19.40 41.5 µM 7.13E-54 TRP & mitochondrial translation 4 8.52E-84
5 SGTC_1882 5615643 16.60 20.0 µM 4.63E-40 TRP & mitochondrial translation 4 3.65E-62
6 SGTC_768 0384-0033 16.10 77.3 µM 7.49E-38 fatty acid desaturase (OLE1) 7 1.05E-58
7 SGTC_505 gw-5074 15.90 63.9 µM 4.00E-37 8 1.45E-57
8 SGTC_2776 terbinafine 15.90 19.9 µM 9.41E-37 cell wall signaling 5 5.55E-57
9 SGTC_1881 5652484 15.80 16.0 µM 1.90E-36 TRP & mitochondrial translation 2 1.66E-56
10 SGTC_2056 5235370 15.80 200.0 µM 2.08E-36 2 1.92E-56
11 SGTC_2540 epiandrosterone 15.70 100.0 µM 4.88E-36 5 7.32E-56
12 SGTC_2472 5377652 14.90 49.4 µM 1.34E-32 TRP & mitochondrial translation 3 1.80E-50
13 SGTC_2607 solasodine 14.80 47.4 µM 4.17E-32 9 1.06E-49
14 SGTC_2038 4100038 14.20 31.0 µM 5.69E-30 plasma membrane duress 10 2.35E-46
15 SGTC_1219 1469-0211 14.10 33.1 µM 3.36E-29 2 3.81E-45
16 SGTC_1715 st032160 12.60 10.2 µM 6.46E-24 2 7.31E-37
17 SGTC_767 0929-0023 12.60 86.0 µM 1.02E-23 TRP & mitochondrial translation 1 1.51E-36
18 SGTC_161 4065-0411 12.30 162.2 µM 1.02E-22 3 5.58E-35
19 SGTC_1636 st007707 12.30 68.9 µM 1.19E-22 7 7.01E-35
20 SGTC_2778 tioconazole 12.20 65.1 nM 2.00E-22 ergosterol depletion effects on membrane 8 1.59E-34

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.696 0 YDR007W TRP1 hom Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
0.672 0 YDR008C_d YDR008C_d hom Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
0.638 0 YKR026C GCN3 hom Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
0.634 0 YDR283C GCN2 hom Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control
0.633 0 YDR354W TRP4 hom Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
0.621 0 YDR127W ARO1 hom Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
0.610 0 YEL009C GCN4 hom Basic leucine zipper (bZIP) transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
0.606 0 YKL211C TRP3 hom Indole-3-glycerol-phosphate synthase; forms bifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
0.539 2.13E-251 YER090W TRP2 hom Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p
0.476 3.85E-189 YFR009W GCN20 hom Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA
0.466 7.39E-180 YGL117W_p YGL117W_p hom Putative protein of unknown function
0.442 4.09E-160 YDR035W ARO3 hom 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan
0.397 9.11E-127 YGL148W ARO2 hom Bifunctional chorismate synthase and flavin reductase; catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids; protein abundance increases in response to DNA replication stress
0.209 1.91E-34 YMR071C TVP18 hom Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments
0.203 1.25E-32 YDL226C GCS1 hom ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p