YKL028W / TFA1

TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening

Zygosity: Heterozygous strain
fixedexpanded
Profile for YKL028W / TFA1

Click on Significant Values for Screen Details ID:SGTC_36|Compound:0335-0881|FD-Score:7.60|P-value:1.18E-14 ID:SGTC_37|Compound:0566-0070|FD-Score:-4.20|P-value:1.53E-5 ID:SGTC_42|Compound:0133-0086|FD-Score:3.92|P-value:3.95E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:4.30|P-value:7.56E-6 ID:SGTC_103|Compound:0844-0104|FD-Score:-4.01|P-value:3.38E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:5.69|P-value:5.40E-9 ID:SGTC_157|Compound:1348-1695|FD-Score:4.28|P-value:8.26E-6 ID:SGTC_163|Compound:1327-0036|FD-Score:7.54|P-value:1.80E-14 ID:SGTC_168|Compound:3970-0862|FD-Score:11.00|P-value:2.03E-28 ID:SGTC_177|Compound:1327-0068|FD-Score:-3.52|P-value:2.36E-4 ID:SGTC_184|Compound:1494-0393|FD-Score:3.48|P-value:2.21E-4 ID:SGTC_197|Compound:4544-0043|FD-Score:5.04|P-value:2.02E-7 ID:SGTC_227|Compound:fluconazole|FD-Score:8.12|P-value:1.72E-16 ID:SGTC_257|Compound:daunorubicin|FD-Score:-3.90|P-value:5.32E-5 ID:SGTC_268|Compound:camptothecin|FD-Score:3.47|P-value:2.33E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:-4.18|P-value:1.65E-5 ID:SGTC_312|Compound:4092-0653|FD-Score:3.47|P-value:2.37E-4 ID:SGTC_320|Compound:4092-0846|FD-Score:4.57|P-value:2.07E-6 ID:SGTC_422|Compound:cantharidin|FD-Score:3.16|P-value:7.02E-4 ID:SGTC_518|Compound:1021-0119|FD-Score:4.66|P-value:1.36E-6 ID:SGTC_558|Compound:k064-0027|FD-Score:3.08|P-value:9.39E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:4.59|P-value:1.90E-6 ID:SGTC_601|Compound:0986-0029|FD-Score:3.42|P-value:2.79E-4 ID:SGTC_634|Compound:1611-4317|FD-Score:4.86|P-value:5.01E-7 ID:SGTC_637|Compound:1181-0519|FD-Score:4.49|P-value:3.15E-6 ID:SGTC_660|Compound:4031-1742|FD-Score:3.73|P-value:8.55E-5 ID:SGTC_740|Compound:k014-0057|FD-Score:3.37|P-value:3.43E-4 ID:SGTC_745|Compound:0469-0705|FD-Score:3.25|P-value:5.23E-4 ID:SGTC_792|Compound:4534-1957|FD-Score:-3.22|P-value:7.09E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:4.26|P-value:8.75E-6 ID:SGTC_1009|Compound:4106-0057|FD-Score:3.15|P-value:7.25E-4 ID:SGTC_1019|Compound:4262-0212|FD-Score:3.21|P-value:6.07E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:3.10|P-value:8.80E-4 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.27|P-value:8.40E-6 ID:SGTC_1113|Compound:artemisinin|FD-Score:4.76|P-value:8.12E-7 ID:SGTC_1133|Compound:3473-0247|FD-Score:5.00|P-value:2.41E-7 ID:SGTC_1154|Compound:4088-0362|FD-Score:-3.26|P-value:6.04E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:-5.19|P-value:1.20E-7 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.02|P-value:2.50E-5 ID:SGTC_1282|Compound:0886-0010|FD-Score:4.78|P-value:7.52E-7 ID:SGTC_1283|Compound:0922-0125|FD-Score:4.00|P-value:2.76E-5 ID:SGTC_1317|Compound:1273-0028|FD-Score:3.49|P-value:2.14E-4 ID:SGTC_1333|Compound:1482-0047|FD-Score:-3.19|P-value:7.69E-4 ID:SGTC_1346|Compound:1488-2224|FD-Score:6.42|P-value:5.60E-11 ID:SGTC_1374|Compound:2889-5571|FD-Score:4.23|P-value:1.04E-5 ID:SGTC_1390|Compound:3413-2614|FD-Score:4.20|P-value:1.18E-5 ID:SGTC_1479|Compound:0549-0158|FD-Score:3.82|P-value:5.83E-5 ID:SGTC_1500|Compound:4488-1866|FD-Score:3.36|P-value:3.47E-4 ID:SGTC_1509|Compound:1326-1131|FD-Score:3.52|P-value:1.93E-4 ID:SGTC_1512|Compound:0259-0544|FD-Score:-4.49|P-value:4.01E-6 ID:SGTC_1513|Compound:0337-0559|FD-Score:-3.64|P-value:1.51E-4 ID:SGTC_1556|Compound:plumbagin|FD-Score:3.27|P-value:4.90E-4 ID:SGTC_1635|Compound:st007035|FD-Score:4.20|P-value:1.16E-5 ID:SGTC_1707|Compound:st032323|FD-Score:6.93|P-value:1.74E-12 ID:SGTC_1745|Compound:st081495|FD-Score:-3.37|P-value:4.13E-4 ID:SGTC_1750|Compound:st081859|FD-Score:-5.92|P-value:1.93E-9 ID:SGTC_1834|Compound:st055981|FD-Score:3.26|P-value:5.03E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:8.16|P-value:1.31E-16 ID:SGTC_1884|Compound:5633444|FD-Score:6.43|P-value:5.04E-11 ID:SGTC_1955|Compound:wogonin|FD-Score:3.35|P-value:3.66E-4 ID:SGTC_2084|Compound:5306078|FD-Score:3.36|P-value:3.51E-4 ID:SGTC_2089|Compound:5281248|FD-Score:-3.76|P-value:9.61E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:4.12|P-value:1.64E-5 ID:SGTC_2186|Compound:6124449|FD-Score:4.13|P-value:1.58E-5 ID:SGTC_2226|Compound:7298446|FD-Score:3.09|P-value:8.89E-4 ID:SGTC_2229|Compound:7354935|FD-Score:3.26|P-value:5.02E-4 ID:SGTC_2248|Compound:tofa|FD-Score:5.40|P-value:2.75E-8 ID:SGTC_2267|Compound:7931562|FD-Score:-4.51|P-value:3.71E-6 ID:SGTC_2277|Compound:7947813|FD-Score:7.48|P-value:2.88E-14 ID:SGTC_2348|Compound:9022543|FD-Score:3.61|P-value:1.37E-4 ID:SGTC_2408|Compound:sulbentine|FD-Score:-5.98|P-value:1.29E-9 ID:SGTC_2413|Compound:inermin|FD-Score:-3.63|P-value:1.58E-4 ID:SGTC_2437|Compound:5741531|FD-Score:3.27|P-value:4.89E-4 ID:SGTC_2485|Compound:5633444|FD-Score:4.88|P-value:4.57E-7 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:-3.68|P-value:1.27E-4 ID:SGTC_2544|Compound:sphondin|FD-Score:4.25|P-value:9.49E-6 ID:SGTC_2563|Compound:tomatine|FD-Score:4.24|P-value:9.55E-6 ID:SGTC_2582|Compound:agaric acid|FD-Score:12.30|P-value:1.73E-35 ID:SGTC_2584|Compound:androsterone|FD-Score:4.03|P-value:2.48E-5 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.24|P-value:6.83E-17 ID:SGTC_2654|Compound:protoveratrine a|FD-Score:3.85|P-value:5.13E-5 ID:SGTC_2662|Compound:daunorubicin|FD-Score:-5.75|P-value:5.07E-9 ID:SGTC_2671|Compound:danthron|FD-Score:4.80|P-value:6.94E-7 ID:SGTC_2679|Compound:rapamycin|FD-Score:4.01|P-value:2.61E-5 ID:SGTC_2688|Compound:kanamycin b|FD-Score:-6.23|P-value:2.79E-10 ID:SGTC_2757|Compound:clomiphene|FD-Score:4.08|P-value:1.95E-5 ID:SGTC_2855|Compound:9016525|FD-Score:-3.59|P-value:1.84E-4 ID:SGTC_2912|Compound:7964298|FD-Score:4.93|P-value:3.48E-7 ID:SGTC_2947|Compound:9072639|FD-Score:3.70|P-value:9.49E-5 ID:SGTC_3000|Compound:9075062|FD-Score:3.67|P-value:1.07E-4 ID:SGTC_3018|Compound:9082602|FD-Score:3.72|P-value:8.78E-5 ID:SGTC_3247|Compound:9135149|FD-Score:3.49|P-value:2.13E-4 ID:SGTC_36|Compound:0335-0881|FD-Score:7.60|P-value:1.18E-14 ID:SGTC_37|Compound:0566-0070|FD-Score:-4.20|P-value:1.53E-5 ID:SGTC_42|Compound:0133-0086|FD-Score:3.92|P-value:3.95E-5 ID:SGTC_58|Compound:0957-0393|FD-Score:4.30|P-value:7.56E-6 ID:SGTC_103|Compound:0844-0104|FD-Score:-4.01|P-value:3.38E-5 ID:SGTC_138|Compound:0850-0259|FD-Score:5.69|P-value:5.40E-9 ID:SGTC_157|Compound:1348-1695|FD-Score:4.28|P-value:8.26E-6 ID:SGTC_163|Compound:1327-0036|FD-Score:7.54|P-value:1.80E-14 ID:SGTC_168|Compound:3970-0862|FD-Score:11.00|P-value:2.03E-28 ID:SGTC_177|Compound:1327-0068|FD-Score:-3.52|P-value:2.36E-4 ID:SGTC_184|Compound:1494-0393|FD-Score:3.48|P-value:2.21E-4 ID:SGTC_197|Compound:4544-0043|FD-Score:5.04|P-value:2.02E-7 ID:SGTC_227|Compound:fluconazole|FD-Score:8.12|P-value:1.72E-16 ID:SGTC_257|Compound:daunorubicin|FD-Score:-3.90|P-value:5.32E-5 ID:SGTC_268|Compound:camptothecin|FD-Score:3.47|P-value:2.33E-4 ID:SGTC_309|Compound:k408-0051|FD-Score:-4.18|P-value:1.65E-5 ID:SGTC_312|Compound:4092-0653|FD-Score:3.47|P-value:2.37E-4 ID:SGTC_320|Compound:4092-0846|FD-Score:4.57|P-value:2.07E-6 ID:SGTC_422|Compound:cantharidin|FD-Score:3.16|P-value:7.02E-4 ID:SGTC_518|Compound:1021-0119|FD-Score:4.66|P-value:1.36E-6 ID:SGTC_558|Compound:k064-0027|FD-Score:3.08|P-value:9.39E-4 ID:SGTC_586|Compound:0957-0265|FD-Score:4.59|P-value:1.90E-6 ID:SGTC_601|Compound:0986-0029|FD-Score:3.42|P-value:2.79E-4 ID:SGTC_634|Compound:1611-4317|FD-Score:4.86|P-value:5.01E-7 ID:SGTC_637|Compound:1181-0519|FD-Score:4.49|P-value:3.15E-6 ID:SGTC_660|Compound:4031-1742|FD-Score:3.73|P-value:8.55E-5 ID:SGTC_740|Compound:k014-0057|FD-Score:3.37|P-value:3.43E-4 ID:SGTC_745|Compound:0469-0705|FD-Score:3.25|P-value:5.23E-4 ID:SGTC_792|Compound:4534-1957|FD-Score:-3.22|P-value:7.09E-4 ID:SGTC_829|Compound:1635-0120|FD-Score:4.26|P-value:8.75E-6 ID:SGTC_1009|Compound:4106-0057|FD-Score:3.15|P-value:7.25E-4 ID:SGTC_1019|Compound:4262-0212|FD-Score:3.21|P-value:6.07E-4 ID:SGTC_1044|Compound:1222-0021|FD-Score:3.10|P-value:8.80E-4 ID:SGTC_1067|Compound:clotrimazole|FD-Score:4.27|P-value:8.40E-6 ID:SGTC_1113|Compound:artemisinin|FD-Score:4.76|P-value:8.12E-7 ID:SGTC_1133|Compound:3473-0247|FD-Score:5.00|P-value:2.41E-7 ID:SGTC_1154|Compound:4088-0362|FD-Score:-3.26|P-value:6.04E-4 ID:SGTC_1161|Compound:k007-0610|FD-Score:-5.19|P-value:1.20E-7 ID:SGTC_1230|Compound:0170-0365|FD-Score:4.02|P-value:2.50E-5 ID:SGTC_1282|Compound:0886-0010|FD-Score:4.78|P-value:7.52E-7 ID:SGTC_1283|Compound:0922-0125|FD-Score:4.00|P-value:2.76E-5 ID:SGTC_1317|Compound:1273-0028|FD-Score:3.49|P-value:2.14E-4 ID:SGTC_1333|Compound:1482-0047|FD-Score:-3.19|P-value:7.69E-4 ID:SGTC_1346|Compound:1488-2224|FD-Score:6.42|P-value:5.60E-11 ID:SGTC_1374|Compound:2889-5571|FD-Score:4.23|P-value:1.04E-5 ID:SGTC_1390|Compound:3413-2614|FD-Score:4.20|P-value:1.18E-5 ID:SGTC_1479|Compound:0549-0158|FD-Score:3.82|P-value:5.83E-5 ID:SGTC_1500|Compound:4488-1866|FD-Score:3.36|P-value:3.47E-4 ID:SGTC_1509|Compound:1326-1131|FD-Score:3.52|P-value:1.93E-4 ID:SGTC_1512|Compound:0259-0544|FD-Score:-4.49|P-value:4.01E-6 ID:SGTC_1513|Compound:0337-0559|FD-Score:-3.64|P-value:1.51E-4 ID:SGTC_1556|Compound:plumbagin|FD-Score:3.27|P-value:4.90E-4 ID:SGTC_1635|Compound:st007035|FD-Score:4.20|P-value:1.16E-5 ID:SGTC_1707|Compound:st032323|FD-Score:6.93|P-value:1.74E-12 ID:SGTC_1745|Compound:st081495|FD-Score:-3.37|P-value:4.13E-4 ID:SGTC_1750|Compound:st081859|FD-Score:-5.92|P-value:1.93E-9 ID:SGTC_1834|Compound:st055981|FD-Score:3.26|P-value:5.03E-4 ID:SGTC_1844|Compound:rapamycin|FD-Score:8.16|P-value:1.31E-16 ID:SGTC_1884|Compound:5633444|FD-Score:6.43|P-value:5.04E-11 ID:SGTC_1955|Compound:wogonin|FD-Score:3.35|P-value:3.66E-4 ID:SGTC_2084|Compound:5306078|FD-Score:3.36|P-value:3.51E-4 ID:SGTC_2089|Compound:5281248|FD-Score:-3.76|P-value:9.61E-5 ID:SGTC_2169|Compound:5-(ethoxymethyl)quinolin-8-ol|FD-Score:4.12|P-value:1.64E-5 ID:SGTC_2186|Compound:6124449|FD-Score:4.13|P-value:1.58E-5 ID:SGTC_2226|Compound:7298446|FD-Score:3.09|P-value:8.89E-4 ID:SGTC_2229|Compound:7354935|FD-Score:3.26|P-value:5.02E-4 ID:SGTC_2248|Compound:tofa|FD-Score:5.40|P-value:2.75E-8 ID:SGTC_2267|Compound:7931562|FD-Score:-4.51|P-value:3.71E-6 ID:SGTC_2277|Compound:7947813|FD-Score:7.48|P-value:2.88E-14 ID:SGTC_2348|Compound:9022543|FD-Score:3.61|P-value:1.37E-4 ID:SGTC_2408|Compound:sulbentine|FD-Score:-5.98|P-value:1.29E-9 ID:SGTC_2413|Compound:inermin|FD-Score:-3.63|P-value:1.58E-4 ID:SGTC_2437|Compound:5741531|FD-Score:3.27|P-value:4.89E-4 ID:SGTC_2485|Compound:5633444|FD-Score:4.88|P-value:4.57E-7 ID:SGTC_2510|Compound:benzyl isothiocyanate|FD-Score:-3.68|P-value:1.27E-4 ID:SGTC_2544|Compound:sphondin|FD-Score:4.25|P-value:9.49E-6 ID:SGTC_2563|Compound:tomatine|FD-Score:4.24|P-value:9.55E-6 ID:SGTC_2582|Compound:agaric acid|FD-Score:12.30|P-value:1.73E-35 ID:SGTC_2584|Compound:androsterone|FD-Score:4.03|P-value:2.48E-5 ID:SGTC_2651|Compound:1327-0036|FD-Score:8.24|P-value:6.83E-17 ID:SGTC_2654|Compound:protoveratrine a|FD-Score:3.85|P-value:5.13E-5 ID:SGTC_2662|Compound:daunorubicin|FD-Score:-5.75|P-value:5.07E-9 ID:SGTC_2671|Compound:danthron|FD-Score:4.80|P-value:6.94E-7 ID:SGTC_2679|Compound:rapamycin|FD-Score:4.01|P-value:2.61E-5 ID:SGTC_2688|Compound:kanamycin b|FD-Score:-6.23|P-value:2.79E-10 ID:SGTC_2757|Compound:clomiphene|FD-Score:4.08|P-value:1.95E-5 ID:SGTC_2855|Compound:9016525|FD-Score:-3.59|P-value:1.84E-4 ID:SGTC_2912|Compound:7964298|FD-Score:4.93|P-value:3.48E-7 ID:SGTC_2947|Compound:9072639|FD-Score:3.70|P-value:9.49E-5 ID:SGTC_3000|Compound:9075062|FD-Score:3.67|P-value:1.07E-4 ID:SGTC_3018|Compound:9082602|FD-Score:3.72|P-value:8.78E-5 ID:SGTC_3247|Compound:9135149|FD-Score:3.49|P-value:2.13E-4

Top fitness defect scores for YKL028W deletion by condition

RankScreen IDConditionFD ScoreConc
P-value
Response
Signature
Screen
Rank
Screen
P-value
Screen
Clearance
1 SGTC_2582 agaric acid 12.30 100.0 µM 1.73E-35 redox potentiating 5 2.65E-35 2.23
2 SGTC_168 3970-0862 11.00 530.5 µM 2.03E-28 2 2.95E-28 1.67
3 SGTC_2651 1327-0036 8.24 5.0 µM 6.83E-17 20 8.97E-17 0.27
4 SGTC_1844 rapamycin 8.16 4.0 nM 1.31E-16 13 1.71E-16 0.21
5 SGTC_227 fluconazole 8.12 33.5 µM 1.72E-16 azole & statin 20 2.25E-16 0.08
6 SGTC_36 0335-0881 7.60 14.2 µM 1.18E-14 ubiquinone biosynthesis & proteasome 10 1.51E-14 1.00
7 SGTC_163 1327-0036 7.54 7.5 µM 1.80E-14 24 2.31E-14 0.19
8 SGTC_2277 7947813 7.48 106.9 µM 2.88E-14 RSC complex & mRNA processing 4 3.68E-14 0.78
9 SGTC_1707 st032323 6.93 6.3 µM 1.74E-12 DNA damage response 14 2.18E-12 0.69
10 SGTC_1884 5633444 6.43 25.0 µM 5.04E-11 redox potentiating 5 6.21E-11 0.19
11 SGTC_1346 1488-2224 6.42 62.4 µM 5.60E-11 1 6.90E-11 0.60
12 SGTC_138 0850-0259 5.69 40.9 µM 5.40E-9 cell wall 35 6.49E-9 0.00
13 SGTC_2248 tofa 5.40 1.1 µM 2.75E-8 sphingolipid biosynthesis & PDR1 19 3.27E-8 0.12
14 SGTC_197 4544-0043 5.04 41.6 µM 2.02E-7 endomembrane recycling 15 2.38E-7 0.12
15 SGTC_1133 3473-0247 5.00 50.0 µM 2.41E-7 RSC complex & mRNA processing 32 2.83E-7 0.03
16 SGTC_2912 7964298 4.93 10.9 µM 3.48E-7 cell wall 30 4.08E-7 0.01
17 SGTC_2485 5633444 4.88 17.8 µM 4.57E-7 redox potentiating 7 5.35E-7 0.50
18 SGTC_634 1611-4317 4.86 11.2 µM 5.01E-7 ERG2 4 5.87E-7 0.46
19 SGTC_2671 danthron 4.80 100.0 µM 6.94E-7 DNA damage response 11 8.11E-7 0.25
20 SGTC_1282 0886-0010 4.78 32.4 µM 7.52E-7 endomembrane recycling 9 8.77E-7 0.01

Download Fitness data (tab-delimited text)  (excel)
Cofit Genes
Download Cofitness data (tab-delimited text)  (excel)

Correlation pval ORF Gene Zygosity Description
0.490 7.68E-202 YHR036W BRL1 het Essential nuclear envelope integral membrane protein identified as a suppressor of a conditional mutation in the major karyopherin, CRM1; homologous to and interacts with Brr6p, a nuclear envelope protein involved in nuclear export
0.485 1.47E-197 YJL054W TIM54 het Component of the mitochondrial TIM22 complex involved in insertion of polytopic proteins into the inner membrane
0.240 4.99E-45 YML103C NUP188 hom Subunit of the inner ring of the nuclear pore complex (NPC); contributes to NPC organization and nucleocytoplasmic transport; homologous to human NUP188
0.232 2.57E-42 YNL106C INP52 hom Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain
0.230 1.27E-41 YBR091C TIM12 het Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
0.223 7.12E-39 YJL081C ARP4 het Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
0.219 7.11E-38 YDR172W SUP35 het Translation termination factor eRF3, has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that alters translational fidelity and results in a nonsense suppressor phenotype
0.213 1.14E-35 YOL003C PFA4 hom Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases
0.212 1.39E-35 YIR008C PRI1 het Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
0.208 2.73E-34 YLL043W FPS1 hom Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress
0.203 1.07E-32 YJR013W GPI14 het Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M
0.203 1.57E-32 YLR331C_d JIP3_d hom Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2
0.197 8.59E-31 YDL147W RPN5 het Subunit of the COP9 signalosome (CSN) and non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p; Rpn5p is an essential protein
0.195 4.24E-30 YJL101C GSH1 hom Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress
0.188 3.77E-28 YCR033W SNT1 hom Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein; mutant has increased aneuploidy tolerance