Yeast Fitness

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Enter orf / gene / drug:

(e.g. pex22 or lovastatin)  
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Welcome to the Yeast Fitness Database.

FitDB is a searchable database of quantitative chemical-genetic interactions based on data in Hillenmeyer et al. (Science 2008). This site provides a graphical interface to the supplementary data presented in The Chemical Genomic Portrait of Yeast. To download the entire dataset, please visit the supplementary website.

A gene search allows viewing of compounds most sensitive to the gene specified in a heterozygous and homozygous yeast deletion strain, including a view of yeast deletion strains that behave similarly to the gene of interest. Compounds can also be searched to identify heterozygous or homozygous deletion strains exhibiting hypersensitivity to compound, including a view of compounds that behave similarly to the compound of interest.

To use FitDB:

  • Search for a gene or drug using the Quick Search box above

  • Perform an advanced search

This site is best viewed with Firefox.